Milli-Mark™ Pan Neuronal Marker | EMD Millipore MAB2300 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Milli-Mark™ Pan Neuronal Marker

catalog :

MAB2300

quantity :

100 µL

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

citations: 16

Published Application/Species/Sample/Dilution	Reference
immunocytochemistry; mouse; 1:500; loading ...; fig 3b	López González M, Soula A, Landry M, Favereaux A. Oxaliplatin treatment impairs extension of sensory neuron neurites in vitro through miR-204 overexpression. Neurotoxicology. 2018;68:91-100 pubmed publisher
immunocytochemistry; mouse; 1:300; fig 8a,8f	Perland E, Hellsten S, Lekholm E, Eriksson M, Arapi V, Fredriksson R. The Novel Membrane-Bound Proteins MFSD1 and MFSD3 are Putative SLC Transporters Affected by Altered Nutrient Intake. J Mol Neurosci. 2017;61:199-214 pubmed publisher
immunocytochemistry; human; 1:100; fig 3 immunohistochemistry - frozen section; mouse; 1:100; fig 2	Cheng Y, Huang C, Lee Y, Tien L, Ku W, Chien R, et al. Knocking down of heat-shock protein 27 directs differentiation of functional glutamatergic neurons from placenta-derived multipotent cells. Sci Rep. 2016;6:30314 pubmed publisher
immunohistochemistry - frozen section; rat; 1:1000	Ziebell J, Taylor S, Cao T, Harrison J, Lifshitz J. Rod microglia: elongation, alignment, and coupling to form trains across the somatosensory cortex after experimental diffuse brain injury. J Neuroinflammation. 2012;9:247 pubmed publisher
	Lekholm E, Perland E, Eriksson M, Hellsten S, Lindberg F, Rostami J, et al. Putative Membrane-Bound Transporters MFSD14A and MFSD14B Are Neuronal and Affected by Nutrient Availability. Front Mol Neurosci. 2017;10:11 pubmed publisher
	BÃ¸ttger P, Glerup S, Gesslein B, Illarionova N, Isaksen T, Heuck A, et al. Glutamate-system defects behind psychiatric manifestations in a familial hemiplegic migraine type 2 disease-mutation mouse model. Sci Rep. 2016;6:22047 pubmed publisher
	Ray B, Chopra N, Long J, Lahiri D. Human primary mixed brain cultures: preparation, differentiation, characterization and application to neuroscience research. Mol Brain. 2014;7:63 pubmed publisher
	Ong E, Xue L, Olmstead M, Cahill C. Prolonged morphine treatment alters ? opioid receptor post-internalization trafficking. Br J Pharmacol. 2015;172:615-29 pubmed publisher
	Gomez Pinedo U, Yanez M, Matias Guiu J, Galan L, Guerrero Sola A, Benito Martin M, et al. Cellular changes in motor neuron cell culture produced by cytotoxic cerebrospinal fluid from patients with amyotrophic lateral sclerosis. Neurologia. 2014;29:346-52 pubmed publisher
	Narla S, Klejbor I, Birkaya B, Lee Y, Morys J, Stachowiak E, et al. Activation of developmental nuclear fibroblast growth factor receptor 1 signaling and neurogenesis in adult brain by ?7 nicotinic receptor agonist. Stem Cells Transl Med. 2013;2:776-88 pubmed publisher
	Perez S, Raghanti M, Hof P, Kramer L, Ikonomovic M, Lacor P, et al. Alzheimer's disease pathology in the neocortex and hippocampus of the western lowland gorilla (Gorilla gorilla gorilla). J Comp Neurol. 2013;521:4318-38 pubmed publisher
	Dursun E, Gezen Ak D, Yilmazer S. A new mechanism for amyloid-? induction of iNOS: vitamin D-VDR pathway disruption. J Alzheimers Dis. 2013;36:459-74 pubmed publisher
	Gezen Ak D, Dursun E, Yilmazer S. Vitamin D inquiry in hippocampal neurons: consequences of vitamin D-VDR pathway disruption on calcium channel and the vitamin D requirement. Neurol Sci. 2013;34:1453-8 pubmed publisher
	Gezen Ak D, Dursun E, Yilmazer S. The effects of vitamin D receptor silencing on the expression of LVSCC-A1C and LVSCC-A1D and the release of NGF in cortical neurons. PLoS ONE. 2011;6:e17553 pubmed publisher
	Dursun E, Gezen Ak D, Yilmazer S. A novel perspective for Alzheimer's disease: vitamin D receptor suppression by amyloid-? and preventing the amyloid-? induced alterations by vitamin D in cortical neurons. J Alzheimers Dis. 2011;23:207-19 pubmed publisher
	Alirezaei M, Kemball C, Flynn C, Wood M, Whitton J, Kiosses W. Short-term fasting induces profound neuronal autophagy. Autophagy. 2010;6:702-10 pubmed

product information

Catalog Number :

MAB2300

Subcategory :

Neuroscience

Product Name :

Milli-Mark™ Pan Neuronal Marker

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Host Name :

Mouse

Antigen :

Pan Neuronal Marker

Conjugate :

Purified

Isotype :

IgG1

Product Description :

Milli-Mark™ Pan Neuronal Marker

Cross Reactivity :

Human;Rat;Mouse

Background :

Antibodies to neuronal proteins have become critical tools for identifying neurons and discerning morphological characteristics in culture and complex tissue. While the labeling from classic histological techniques such as Golgi staining and modern molecular approaches such as GFP constructs yield excellent cytoarchitectural detail, these approaches are technically challenging and impractical for many neuroscience research needs. Neuron-specific antibodies are convenient precision tools useful in revealing cytoarchitecture, but are limited to the protein target distribution within the neuron, which may differ greatly from nucleus to soma to dendrite and axon. To achieve as complete a morphological staining as possible across all parts of neurons, Millipore has developed a monoclonal antibody blend that reacts against key somatic, nuclear, dendritic, and axonal proteins distributed across the pan-neuronal architecture that can then be detected by a single secondary antibody. This antibody cocktail has been validated in diverse fixations, cell culture and immunohistochemistry protocols, including archival brain tissue, giving researchers a convienent and specific qualitative and quantitative tool for studying neuronal morphology.

Specificity :

Cat. # MAB2300 is specific to axons (neurites), dendrites, nucleus, and the cell body of neurons.

Package Size :

100 µL

Uses :

Immunocytochemistry;Immunohistochemistry;Immunofluorescence;Immunohistochemistry (Paraffin)

Storage :

Maintain at 2-8°C for up to 1 year from date of receipt.