Integrin α3 Antibody, cytoplasmic domain, clone 54B3 | EMD Millipore MAB2291 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Integrin α3 Antibody, cytoplasmic domain, clone 54B3

catalog :

MAB2291

quantity :

100 µg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

54B3

The same clone is also sold as:

Santa Cruz Biotechnology: sc-59967
Abcam: ab8988
LifeSpan Biosciences: LS-C146758, LS-C24753
OriGene: BM6025P

reactivity :

human

application :

western blot, immunohistochemistry, immunocytochemistry

citations: 1

Reference
Zhang W, Xiao H, Parkin K. Apoptosis in MCF-7 breast cancer cells induced by S-alkenylmercaptocysteine (CySSR) species derived from Allium tissues in combination with sodium selenite. Food Chem Toxicol. 2014;68:1-10 pubmed publisher

product information

Catalog Number :

MAB2291

Subcategory :

Cell Structure

Product Name :

Anti-Integrin α3 Antibody, cytoplasmic domain, clone 54B3

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P26006

Host Name :

Mouse

Antigen :

Integrin α3

Clone :

54B3

Conjugate :

Purified

Isotype :

IgG1

Product Description :

Anti-Integrin α3 Antibody, cytoplasmic domain, clone 54B3

Cross Reactivity :

Human

Background :

Integrins are a family of heterodimeric membrane glycoproteins consisting of non-covalently associated alpha and beta subunits. More than 18 alpha and 8 beta subunits with numerous splice variant isoforms have been identified in mammals. In general, integrins function as receptors for extracellular matrix proteins. Certain integrins can also bind to soluble ligands or to counter-receptors on adjacent cells, such as the intracellular adhesion molecules (ICAMs), resulting in aggregation of cells. Signals transduced by integrins play a role in many biological processes, including cell growth, differentiation, migration and apoptosis. For integrin subunits alpha 3 and alpha 6, two cytoplasmic variants, A and B, have been identified.

ALT Names :

CD49c

Immunogen :

Synthetic peptide: CTRYYQIMPKYHAVRIREEERYPPPGSTLPTKK

Specificity :

Anti-Integrin alpha 3B recognizes the cytoplasmic domain of integrin alpha 3B. Integrin alpha 3B is present in the microvascular structures in brain and heart. SPECIES REACTIVITIES: Although untested, a broad species reactivity is expected due to the conserved nature of the epitope.

Package Size :

100 µg

Uses :

Western Blotting;Immunocytochemistry;Immunohistochemistry

Storage :

Store at 2-8°C, or in small aliquots at -20°C.