Peripheral Myelin Protein 22 (PMP22) Antibody, clone CF1 | EMD Millipore MAB2265 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Peripheral Myelin Protein 22 (PMP22) Antibody, clone CF1

catalog :

MAB2265

quantity :

100 μg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

CF1

The same clone is also sold as:

LifeSpan Biosciences: LS-C140125, LS-C122324
Abcam: ab90782
OriGene: AM26200PU-N
MilliporeSigma: P0081

reactivity :

human

application :

immunohistochemistry

product information

Catalog Number :

MAB2265

Subcategory :

Neuroscience

Product Name :

Anti-Peripheral Myelin Protein 22 (PMP22) Antibody, clone CF1

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

Q01453

Host Name :

Mouse

Antigen :

Peripheral Myelin Protein 22 (PMP22)

Clone :

CF1

Conjugate :

Purified

Isotype :

IgG1κ

Product Description :

Anti-Peripheral Myelin Protein 22 (PMP22) Antibody, clone CF1

Cross Reactivity :

Human

Background :

Peripheral myelin protein 22 (PMP22), a 160 amino acid glycoprotein, belongs to the claudin family of proteins. PMP22 is thought to have a critical role in external mesaxon formation during development as well as potential involvement in the progression of axon myelination. This glycoprotein has four hydrophobic domains a feature which gives rise to another potential role for PMP22 in the structure of peripheral nerve myelin. PMP22 has been observed in compact myelin found within the peripheral nerve of human adult, and has been noted as having a distribution similar to that of myelin Protein zero (PO). Defects in PMP-22 expression are causal to several hereditary demyelinating neuropathies including; inflammatory demyelinating polyneuropathy (IDP), hereditary neuropathy with liability to pressure palsies (HNPP), Charcot-Marie-Tooth disease Type 1A (CMT1A) and type 1E (CMT1E), and Dejerine-Sottas syndrome (DSS).

ALT Names :

peripheral myelin protein 22;Growth arrest-specific protein 3;growth arrest-specific 3

Immunogen :

Human PMP22 cDNA boosted with 13-mer peptide of the second extracellular domain of PMP22

Specificity :

This antibody recognizes peripheral myelin protein 22 (PMP22)

Package Size :

100 μg

Uses :

Immunohistochemistry

Storage :

Stable for 1 year at 2-8°C from date of receipt