This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
EMD Millipore
other brands :
Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava
product type :
antibody
product name :
Integrin β1 Antibody, clone 21C8
catalog :
MAB2250
quantity :
100 µg
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
21C8
reactivity :
human
application :
immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry
citations: 6
Published Application/Species/Sample/DilutionReference
  • immunocytochemistry; human
Burkhalter R, Westfall S, Liu Y, Stack M. Lysophosphatidic Acid Initiates Epithelial to Mesenchymal Transition and Induces β-Catenin-mediated Transcription in Epithelial Ovarian Carcinoma. J Biol Chem. 2015;290:22143-54 pubmed publisher
  • immunoprecipitation; human; 1:100; fig 3
Morris E, Assi K, Salh B, Dedhar S. Integrin-linked kinase links dynactin-1/dynactin-2 with cortical integrin receptors to orient the mitotic spindle relative to the substratum. Sci Rep. 2015;5:8389 pubmed publisher
Saraiva N, Prole D, Carrara G, Johnson B, Taylor C, Parsons M, et al. hGAAP promotes cell adhesion and migration via the stimulation of store-operated Ca2+ entry and calpain 2. J Cell Biol. 2013;202:699-713 pubmed publisher
Browe D, Baumgarten C. EGFR kinase regulates volume-sensitive chloride current elicited by integrin stretch via PI-3K and NADPH oxidase in ventricular myocytes. J Gen Physiol. 2006;127:237-51 pubmed
Browe D, Baumgarten C. Angiotensin II (AT1) receptors and NADPH oxidase regulate Cl- current elicited by beta1 integrin stretch in rabbit ventricular myocytes. J Gen Physiol. 2004;124:273-87 pubmed
Browe D, Baumgarten C. Stretch of beta 1 integrin activates an outwardly rectifying chloride current via FAK and Src in rabbit ventricular myocytes. J Gen Physiol. 2003;122:689-702 pubmed
product information
Catalog Number :
MAB2250
Subcategory :
Cell Structure
Product Name :
Anti-Integrin β1 Antibody, clone 21C8
Product Type :
Antibodies
Clonality :
Monoclonal Antibody
Gene ID :
P55268
Host Name :
Mouse
Antigen :
Integrin β1
Clone :
21C8
Conjugate :
Purified
Isotype :
IgG1
Product Description :
Anti-Integrin β1 Antibody, clone 21C8
Cross Reactivity :
Human
ALT Names :
CD29
Immunogen :
Jurkat T-leukemic cell line
Specificity :
Reacts with the human integrin beta1 subunit. Specificity verified by preclearing of beta1in immunoprecipitation, flow cytometry on transfectant cells displaying human beta1 integrin, and reactivity with purified beta1.
Package Size :
100 µg
Uses :
Flow Cytometry;Immunoprecipitation;Affects Function;Immunohistochemistry
Storage :
Maintain at 2-8°C in undiluted aliquots for up to 6 months.
company information
EMD Millipore
290 Concord Road
Billerica, Massachusetts 01821
bioscienceshelp@emdchemical.com
https://www.emdmillipore.com
888-854-3417
headquarters: United States
EMD Millipore is the Life Science division of Merck KGaA of Darmstadt, Germany

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