GCAP1 Antibody, clone G2 | EMD Millipore MAB2232 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

GCAP1 Antibody, clone G2

catalog :

MAB2232

quantity :

100 μg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

G2

The same clone is also sold as:

Invitrogen: MA1-724

reactivity :

human, mouse, bovine

application :

western blot, immunohistochemistry

product information

Catalog Number :

MAB2232

Subcategory :

Neuroscience

Product Name :

Anti-GCAP1 Antibody, clone G2

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P43080

Host Name :

Mouse

Antigen :

GCAP1

Clone :

Conjugate :

Purified

Isotype :

IgG2aκ

Product Description :

Anti-GCAP1 Antibody, clone G2

Cross Reactivity :

Bovine;Human;Mouse;Rat

Background :

Guanylate cyclase-activating proteins (GCAPs) are calcium binding proteins that belong to the calmodulin super family. GCAPs without calcium are responsible for activation of photoreceptor guanylate cyclase during light adaptation. Studies have shown that the addition or subtraction of Ca2+ results in major conformational changes and the activation/deactivation of GCAP 1 and GCAP 2. It has been demonstrated that both GCAP 1 and 2 act on guanylate cyclase similarly and have approximately 50% homology between the two forms. GCAP 1 is predominantly localized in the photoreceptor outer segments. These results suggest that although GCAP1 is involved in the Ca2+-sensitive regulation of GC in rod and cone outer segments, GCAP2 may have non-phototransduction functions in photoreceptors and inner retinal neurons.

ALT Names :

GCAP 1 ;Guanylate cyclase activator 1A ;guanylate cyclase activator 1A (retina)

Immunogen :

GST-tagged GCAP1.

Specificity :

This antibody recognizes GCAP1.

Package Size :

100 μg

Uses :

Western Blotting;Immunohistochemistry

Storage :

Stable for 1 year at 2-8ºC from date of receipt.