Huntingtin Protein Antibody, a.a. 1247-1646, clone HU-4E6 | EMD Millipore MAB2170 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Huntingtin Protein Antibody, a.a. 1247-1646, clone HU-4E6

catalog :

MAB2170

quantity :

100 µL

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

HU-4E6

reactivity :

human, mouse

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

citations: 5

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry - frozen section; human; loading ...; fig 2a immunoprecipitation; human; loading ...; fig 1b immunocytochemistry; human; loading ...; fig 1j western blot; human; loading ...; fig 1a	Gao R, Chakraborty A, Geater C, Pradhan S, Gordon K, Snowden J, et al. Mutant huntingtin impairs PNKP and ATXN3, disrupting DNA repair and transcription. elife. 2019;8: pubmed publisher
western blot; mouse; 1:1000; fig s3	Budworth H, Harris F, Williams P, Lee D, Holt A, Pahnke J, et al. Suppression of Somatic Expansion Delays the Onset of Pathophysiology in a Mouse Model of Huntington's Disease. PLoS Genet. 2015;11:e1005267 pubmed publisher
	Masnata M, Sciacca G, Maxan A, Bousset L, Denis H, Lauruol F, et al. Demonstration of prion-like properties of mutant huntingtin fibrils in both in vitro and in vivo paradigms. Acta Neuropathol. 2019;137:981-1001 pubmed publisher
	Hohjoh H, Akari H, Fujiwara Y, Tamura Y, Hirai H, Wada K. Molecular cloning and characterization of the common marmoset huntingtin gene. Gene. 2009;432:60-6 pubmed publisher
	Benn C, Sun T, Sadri Vakili G, McFarland K, DiRocco D, Yohrling G, et al. Huntingtin modulates transcription, occupies gene promoters in vivo, and binds directly to DNA in a polyglutamine-dependent manner. J Neurosci. 2008;28:10720-33 pubmed publisher

product information

Catalog Number :

MAB2170

Subcategory :

Neuroscience

Product Name :

Anti-Huntingtin Protein Antibody, a.a. 1247-1646, clone HU-4E6

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P42858

Host Name :

Mouse

Antigen :

Huntingtin Protein

Clone :

HU-4E6

Conjugate :

Ascites

Isotype :

IgG2b

Product Description :

Anti-Huntingtin Protein Antibody, a.a. 1247-1646, clone HU-4E6

Cross Reactivity :

Human;Mouse

Immunogen :

Huntingtin fragment from aa 1247 to 1646 as a fusion protein

Specificity :

Huntingtin Protein. No detectable cross reactivity with other proteins by Western blot.

Package Size :

100 µL

Uses :

ELISA;Immunoprecipitation;Western Blotting;Immunocytochemistry;Immunohistochemistry (Paraffin)

Storage :

Maintain at -20°C in undiluted aliquots up to 12 months after date of receipt. Avoid repeated freeze/thaw cycles. During shipment, small volumes of antibody will occasionally become entrapped in the seal of the product vial. For antibodies with volumes of 200 μl or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container's cap.