E-Selectin Antibody, clone P2H3 | EMD Millipore MAB2150 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

E-Selectin Antibody, clone P2H3

catalog :

MAB2150

quantity :

100 µg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

P2H3

The same clone is also sold as:

Abnova: MAB10896
Santa Cruz Biotechnology: sc-18840, sc-18840 L
Invitrogen: 12-0627-42, 14-0627-95, 14-0627-80, 12-0627-41, 14-0627-37, 14-0627-82
OriGene: TA320457

reactivity :

human

application :

immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry

citations: 8

Published Application/Species/Sample/Dilution	Reference
ELISA; human; 1:50; loading ...; fig 4a	Lee W, Ku S, Bae J. Anti-inflammatory effects of Baicalin, Baicalein, and Wogonin in vitro and in vivo. Inflammation. 2015;38:110-25 pubmed publisher
ELISA; human; 1:50; loading ...; fig 3	Jumpertz S, Hennes T, Asare Y, Vervoorts J, Bernhagen J, Schütz A. The ?-catenin E3 ubiquitin ligase SIAH-1 is regulated by CSN5/JAB1 in CRC cells. Cell Signal. 2014;26:2051-9 pubmed publisher
immunocytochemistry; human; 1:50; loading ...; fig 3a	Lee W, Ku S, Bae J. Vascular barrier protective effects of orientin and isoorientin in LPS-induced inflammation in vitro and in vivo. Vascul Pharmacol. 2014;62:3-14 pubmed publisher
	Lee W, Ku S, Min B, Lee S, Jee J, Kim J, et al. Vascular barrier protective effects of pellitorine in LPS-induced inflammation in vitro and in vivo. Fitoterapia. 2014;92:177-87 pubmed publisher
	He Q, Ao Q, Gong Y, Zhang X. Preparation of chitosan films using different neutralizing solutions to improve endothelial cell compatibility. J Mater Sci Mater Med. 2011;22:2791-802 pubmed publisher
	He Q, Ao Q, Gong K, Zhang L, Hu M, Gong Y, et al. Preparation and characterization of chitosan-heparin composite matrices for blood contacting tissue engineering. Biomed Mater. 2010;5:055001 pubmed publisher
	Mayer T, Jagla B, Wyler M, Kelly P, Aulner N, Beard M, et al. Cell-based assays using primary endothelial cells to study multiple steps in inflammation. Methods Enzymol. 2006;414:266-83 pubmed
	Burns M, DePaola N. Flow-conditioned HUVECs support clustered leukocyte adhesion by coexpressing ICAM-1 and E-selectin. Am J Physiol Heart Circ Physiol. 2005;288:H194-204 pubmed

product information

Catalog Number :

MAB2150

Subcategory :

Cell Structure

Product Name :

Anti-E-Selectin Antibody, clone P2H3

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P16581

Host Name :

Mouse

Antigen :

E-Selectin

Clone :

P2H3

Conjugate :

Purified

Isotype :

IgG1

Product Description :

Anti-E-Selectin Antibody, clone P2H3

Cross Reactivity :

Human

Background :

Leukocytes adhere to the blood vessel endothelium during extravasation in postcapillary venules of lymph nodes. In addition, leukocyte adhesion occurs in the capillaries and small venules at any site in the body after onset of inflammation. This response is immediate and involves a cascade of adhesion receptors. At the endothelial surface, members of the selectin and immunoglobulin superfamilies participate in this cascade. Selectins are C-type cell surface lectins that play a role in leukocyte adhesion to the blood vessel wall endothelium. E-selectin (CD62E) is an endothelial cell specific selectin that is expressed only after activation with proinflammatory cytokines. In vitro experiments have shown that IL-1, TNF alpha and bacterial wall components like lipopolysaccharides induce the transcription of E-selectin in a NK kappa B dependent signaling cascade. E-selectin has been associated with blood vessel endothelium in diverse inflammatory situations.

ALT Names :

ELAM-1; CD62E

Immunogen :

IL-1(1 activated HUVEC (human)

Specificity :

Human E-Selectin

Package Size :

100 µg

Uses :

ELISA;Flow Cytometry;Immunoprecipitation;Immunocytochemistry;Immunohistochemistry;Affects Function

Storage :

Maintain at 2-8°C for up to 12 months from date of receipt.