Integrin αVβ6 Antibody, clone E7P6, azide free | EMD Millipore MAB2074Z product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Integrin αVβ6 Antibody, clone E7P6, azide free

catalog :

MAB2074Z

quantity :

100 µg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

E7P6

reactivity :

human, mouse

application :

immunohistochemistry, immunocytochemistry, flow cytometry

citations: 10

Published Application/Species/Sample/Dilution	Reference
immunocytochemistry; mouse immunohistochemistry; mouse	Wang J, Bao L, Yu B, Liu Z, Han W, Deng C, et al. Interleukin-1β Promotes Epithelial-Derived Alveolar Elastogenesis via αvβ6 Integrin-Dependent TGF-β Activation. Cell Physiol Biochem. 2015;36:2198-216 pubmed publisher
	Jiang X, Teng M, Guo X, Zhang D, Zhang Q, Zhang J, et al. Switch from Î±vÎ²5 to Î±vÎ²6 integrin is required for CD9-regulated keratinocyte migration and MMP-9 activation. FEBS Lett. 2014;588:4044-52 pubmed publisher
	Li H, Zheng J, Fan H, Li H, Gao Z, Chen D. Expression of ?v?6 integrin and collagen fibre in oral squamous cell carcinoma: association with clinical outcomes and prognostic implications. J Oral Pathol Med. 2013;42:547-56 pubmed publisher
	Taherian A, Li X, Liu Y, Haas T. Differences in integrin expression and signaling within human breast cancer cells. BMC Cancer. 2011;11:293 pubmed publisher
	Seitsonen J, Susi P, Heikkilä O, Sinkovits R, Laurinmäki P, Hyypia T, et al. Interaction of alphaVbeta3 and alphaVbeta6 integrins with human parechovirus 1. J Virol. 2010;84:8509-19 pubmed publisher
	Sume S, Kantarci A, Lee A, Hasturk H, Trackman P. Epithelial to mesenchymal transition in gingival overgrowth. Am J Pathol. 2010;177:208-18 pubmed publisher
	Heikkilä O, Susi P, Tevaluoto T, Härmä H, Marjomaki V, Hyypia T, et al. Internalization of coxsackievirus A9 is mediated by {beta}2-microglobulin, dynamin, and Arf6 but not by caveolin-1 or clathrin. J Virol. 2010;84:3666-81 pubmed publisher
	Heikkilä O, Susi P, Stanway G, Hyypia T. Integrin alphaVbeta6 is a high-affinity receptor for coxsackievirus A9. J Gen Virol. 2009;90:197-204 pubmed publisher
	Elayadi A, Samli K, Prudkin L, Liu Y, Bian A, Xie X, et al. A peptide selected by biopanning identifies the integrin alphavbeta6 as a prognostic biomarker for nonsmall cell lung cancer. Cancer Res. 2007;67:5889-95 pubmed
	Fouchier F, Penel C, Pierre Montero M, Bremond P, Champion S. Integrin alphavbeta6 mediates HT29-D4 cell adhesion to MMP-processed fibrinogen in the presence of Mn2+. Eur J Cell Biol. 2007;86:143-60 pubmed

product information

Catalog Number :

MAB2074Z

Subcategory :

Cell Structure

Product Name :

Anti-Integrin αVβ6 Antibody, clone E7P6, azide free

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P06756

Host Name :

Mouse

Antigen :

Integrin αVβ6

Clone :

E7P6

Conjugate :

Purified

Isotype :

IgG1

Product Description :

Anti-Integrin αVβ6 Antibody, clone E7P6, azide free

Cross Reactivity :

Human

ALT Names :

MAB2074

Immunogen :

Recombinant secreted human alphavbeta6.

Specificity :

Monoclonal antibody MAB2074Z, raised by immunizing Balb/c mice with recombinant secreted human avb6, is useful for flow cytometry and is especially useful for immunocytochemistry. The antibody works well for immunohistochemistry of human tissue, especially under circumstances where upregulation of the receptor is being evaluated. The antibody does not stain formalin-fixed or paraffin-embedded tissues, and may not detect the low-level basal expression of alphavbeta6 in epithelia of healthy adults. This antibody does not recognize the alphaV subunit and does not react with alphaV integrins other than alphavbeta6. Because the antibody is not effective in western blot, it is unknown whether the epitope recognized by the antibody localizes to the alphavbeta6 heterodimer or to the beta6 subunit only.

Package Size :

100 µg

Uses :

Flow Cytometry;Immunocytochemistry;Immunohistochemistry

Storage :

Maintain at 2-8°C in undiluted aliquots for up to 12 months.