Integrin B4 Antibody, clone ASC-8, Azide & Ascites Free | EMD Millipore MAB2059-C product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Integrin B4 Antibody, clone ASC-8, Azide & Ascites Free

catalog :

MAB2059-C

quantity :

100 μg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

ASC-8

reactivity :

human

application :

immunohistochemistry, immunoprecipitation, flow cytometry

product information

Catalog Number :

MAB2059-C

Subcategory :

Cell Signaling

Product Name :

Anti-Integrin B4 Antibody, clone ASC-8, Azide & Ascites Free

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P16144

Host Name :

Mouse

Antigen :

ITGB4

Clone :

ASC-8

Conjugate :

Purified

Purification Method :

Protein G purified

Isotype :

IgG1κ

Product Description :

Anti-Integrin B4 Antibody, clone ASC-8, Azide & Ascites Free

Cross Reactivity :

Human

Background :

Integrin proteins couple the ECM outside of a cell to the cytoskeleton inside of the cell. Which ECM protein binds and what signals are conveyed depend upon the particular makeup of the integrin pair being expressed. Functional integrin receptors are made up of two protein chains linked by disulfide bonds, an alpha chain and a beta chain. Integrin beta 4, also known as CD104, or GP160 is one of eight different beta chains, however beta 4 integrin is part of only one principal integrin receptor, integrin alpha6beta4. This receptor is expressed in endothelium, epithelium, and perineurium tissues of several organs as well as fibroblasts and Schwann cells but not in blood or lymphatic cells. Integrin alpha6beta4 is the laminin receptor and is critical for cellular polarity and motility.

ALT Names :

Integrin beta-4, Integrin B4, Integrin Beta4, GP150, CD104

Immunogen :

SCC9 whole cells expressing Integrin B4.

Package Size :

100 μg

Uses :

Flow Cytometry, Inhibition, Immunohistochemistry, Immunoprecipitation

Storage :

Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.