Disialoganglioside GD2 Antibody, clone 14.2Ga, AlexaFluor®488 Conj. | EMD Millipore MAB2052A4 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Disialoganglioside GD2 Antibody, clone 14.2Ga, AlexaFluor®488 Conj.

catalog :

MAB2052A4

quantity :

100 µL

clonality :

monoclonal

host :

mouse

conjugate :

AF488

clone name :

14.2Ga

application :

immunohistochemistry, immunocytochemistry

product information

Catalog Number :

MAB2052A4

Subcategory :

Neuroscience

Product Name :

Anti-Disialoganglioside GD2 Antibody, clone 14.2Ga, AlexaFluor®488 Conj.

Product Type :

Antibodies

Host Name :

Mouse

Antigen :

Disialoganglioside GD2

Clone :

14.2Ga

Conjugate :

AlexaFluor®488

Isotype :

IgG2a

Product Description :

Anti-Disialoganglioside GD2 Antibody, clone 14.2Ga, AlexaFluor®488 Conj.

Cross Reactivity :

Rat;Mouse

Background :

GD2 is expressed on the surfaces of a wide range of tumor cells of neuroectodermal origin, including neuroblastoma, melanomas, and other soft tissue sarcomas. Due to its specific expression on tumor cells, GD2 is an attractive target for immunotherapy. Gangliosides are sialic-acid bearing glycolipids and are likely involved in mediating cell signal transduction events. They are important target antigens for antibody dependent cellular cytotoxicity (ADCC) of human melanoma and neuroblastoma cells. Human melanoma cells produce gangliosides, designated as GD2 and GD3, are deposited in the subtratum-attached material and may play a significant role in the melanoma metastatic phenotype.

ALT Names :

Disialoganglioside GD2

Package Size :

100 µL

Uses :

Immunocytochemistry;Immunohistochemistry

Storage :

Maintain refrigerated at 2-8 °C protected from light in undiluted aliquots for up to 6 months from date of receipt.