Integrin αVβ5 Antibody, clone 15F11, Azide Free | EMD Millipore MAB2019Z product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Integrin αVβ5 Antibody, clone 15F11, Azide Free

catalog :

MAB2019Z

quantity :

100 µg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

15F11

reactivity :

human

application :

immunocytochemistry, immunoprecipitation, flow cytometry

citations: 5

Reference
Stubb A, Guzman C, Närvä E, Aaron J, Chew T, Saari M, et al. Superresolution architecture of cornerstone focal adhesions in human pluripotent stem cells. Nat Commun. 2019;10:4756 pubmed publisher
Taherian A, Li X, Liu Y, Haas T. Differences in integrin expression and signaling within human breast cancer cells. BMC Cancer. 2011;11:293 pubmed publisher
Yang M, Adla S, Temburni M, Patel V, Lagow E, Brady O, et al. Stimulation of glioma cell motility by expression, proteolysis, and release of the L1 neural cell recognition molecule. Cancer Cell Int. 2009;9:27 pubmed publisher
O Prey J, Wilkinson S, Ryan K. Tumor antigen LRRC15 impedes adenoviral infection: implications for virus-based cancer therapy. J Virol. 2008;82:5933-9 pubmed publisher
Zhang H, Li Z, Viklund E, Stromblad S. P21-activated kinase 4 interacts with integrin alpha v beta 5 and regulates alpha v beta 5-mediated cell migration. J Cell Biol. 2002;158:1287-97 pubmed

product information

Catalog Number :

MAB2019Z

Subcategory :

Cell Structure

Product Name :

Anti-Integrin αVβ5 Antibody, clone 15F11, Azide Free

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P06756

Host Name :

Mouse

Antigen :

Integrin αVβ5

Clone :

15F11

Conjugate :

Purified

Product Description :

Anti-Integrin αVβ5 Antibody, clone 15F11, Azide Free

Cross Reactivity :

Human

ALT Names :

MAB2019

Immunogen :

Generated against human integrin alphaVbeta5 purified from placental tissue and depleted of integrin alphaVbeta3.

Specificity :

Reactive with human integrin alphaVbeta5. Does not recognize integrin alphaVbeta3 or alpha5beta1. The antibody binds to the alphaVbeta5 complex. The monoclonal antibody MAB2019Z has a Kd of 2.8 nM in Mn2+, 4.0 nM in Ca2+and 2.9 nM in buffer lacking cation. Thus, cations do not significantly affect the binding of the antibody to alphaVbeta5. Monoclonal antibody MAB2019Z does not block ligand binding to purified alphaVbeta5, nor does it block cell adhesion mediated through this receptor.

Package Size :

100 µg

Uses :

ELISA;Flow Cytometry;Immunoprecipitation;Immunocytochemistry

Storage :

Maintain at 2-8°C in undiluted aliquots for up to 12 months.