This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
EMD Millipore
other brands :
Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava
product type :
antibody
product name :
Integrin α2β1 Antibody, clone BHA2.1, azide free
catalog :
MAB1998Z
quantity :
100 μg
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
BHA2.1
reactivity :
human
application :
immunohistochemistry, immunoprecipitation, flow cytometry, blocking or activating experiments
citations: 27
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human; fig s12
Liu X, Chen X, Rycaj K, Chao H, Deng Q, Jeter C, et al. Systematic dissection of phenotypic, functional, and tumorigenic heterogeneity of human prostate cancer cells. Oncotarget. 2015;6:23959-86 pubmed
  • blocking or activating experiments; human
Toh Y, Xing J, Yu H. Modulation of integrin and E-cadherin-mediated adhesions to spatially control heterogeneity in human pluripotent stem cell differentiation. Biomaterials. 2015;50:87-97 pubmed publisher
Naci D, Aoudjit F. Alpha2beta1 integrin promotes T cell survival and migration through the concomitant activation of ERK/Mcl-1 and p38 MAPK pathways. Cell Signal. 2014;26:2008-15 pubmed publisher
Lee S, Cheng H, Yuan Y, Wu S. Regulation of ionizing radiation-induced adhesion of breast cancer cells to fibronectin by alpha5beta1 integrin. Radiat Res. 2014;181:650-8 pubmed publisher
Poluzzi C, Casulli J, Goyal A, Mercer T, Neill T, Iozzo R. Endorepellin evokes autophagy in endothelial cells. J Biol Chem. 2014;289:16114-28 pubmed publisher
Li X, Ishihara S, Yasuda M, Nishioka T, Mizutani T, Ishikawa M, et al. Lung cancer cells that survive ionizing radiation show increased integrin α2β1- and EGFR-dependent invasiveness. PLoS ONE. 2013;8:e70905 pubmed publisher
Tang S, Lucius R, Wenck H, Gallinat S, Weise J. UV-mediated downregulation of the endocytic collagen receptor, Endo180, contributes to accumulation of extracellular collagen fragments in photoaged skin. J Dermatol Sci. 2013;70:42-8 pubmed publisher
Kemeny S, Cicalese S, Figueroa D, Clyne A. Glycated collagen and altered glucose increase endothelial cell adhesion strength. J Cell Physiol. 2013;228:1727-36 pubmed publisher
Hozumi K, Ishikawa M, Hayashi T, Yamada Y, Katagiri F, Kikkawa Y, et al. Identification of cell adhesive sequences in the N-terminal region of the laminin ?2 chain. J Biol Chem. 2012;287:25111-22 pubmed publisher
Xia H, Seeman J, Hong J, Hergert P, Bodem V, Jessurun J, et al. Low ?(2)?(1) integrin function enhances the proliferation of fibroblasts from patients with idiopathic pulmonary fibrosis by activation of the ?-catenin pathway. Am J Pathol. 2012;181:222-33 pubmed publisher
Labonté L, Li Y, Addison C, Brand M, Javidnia H, Corsten M, et al. Distinct profile of vascular progenitor attachment to extracellular matrix proteins in cancer patients. Clin Invest Med. 2012;35:E86-95 pubmed
Goswami R, Bajjuri K, Forsyth J, Das S, Hassenpflug W, Huang Z, et al. Chemically programmed antibodies targeting multiple alpha(v) integrins and their effects on tumor-related functions in vitro. Bioconjug Chem. 2011;22:1535-44 pubmed publisher
Lord M, Cheng B, McCarthy S, Jung M, Whitelock J. The modulation of platelet adhesion and activation by chitosan through plasma and extracellular matrix proteins. Biomaterials. 2011;32:6655-62 pubmed publisher
Yamada Y, Katagiri F, Hozumi K, Kikkawa Y, Nomizu M. Cell behavior on protein matrices containing laminin ?1 peptide AG73. Biomaterials. 2011;32:4327-35 pubmed publisher
Rybak A, He L, Kapoor A, Cutz J, Tang D. Characterization of sphere-propagating cells with stem-like properties from DU145 prostate cancer cells. Biochim Biophys Acta. 2011;1813:683-94 pubmed publisher
Lu S, Li F, Yin H, Feng Q, Kimbrel E, Hahm E, et al. Platelets generated from human embryonic stem cells are functional in vitro and in the microcirculation of living mice. Cell Res. 2011;21:530-45 pubmed publisher
Chen S, Tsai Y, Wu C, Liao S, Wu L, Chang C, et al. Streptococcal collagen-like surface protein 1 promotes adhesion to the respiratory epithelial cell. BMC Microbiol. 2010;10:320 pubmed publisher
Lim S, Kreipe B, Trzeciakowski J, DANGOTT L, Trache A. Extracellular matrix effect on RhoA signaling modulation in vascular smooth muscle cells. Exp Cell Res. 2010;316:2833-48 pubmed publisher
de Neergaard M, Kim J, Villadsen R, Fridriksdottir A, Rank F, Timmermans Wielenga V, et al. Epithelial-stromal interaction 1 (EPSTI1) substitutes for peritumoral fibroblasts in the tumor microenvironment. Am J Pathol. 2010;176:1229-40 pubmed publisher
Ko S, Lengyel E, Naora H. The Müllerian HOXA10 gene promotes growth of ovarian surface epithelial cells by stimulating epithelial-stromal interactions. Mol Cell Endocrinol. 2010;317:112-9 pubmed publisher
Gaide Chevronnay H, Galant C, Lemoine P, Courtoy P, Marbaix E, Henriet P. Spatiotemporal coupling of focal extracellular matrix degradation and reconstruction in the menstrual human endometrium. Endocrinology. 2009;150:5094-105 pubmed publisher
Chen Y, Zhang J, Wang Y, Zhang L, Julien R, Tang K, et al. Real-time monitoring approach: assessment of effects of antibodies on the adhesion of NCI-H460 cancer cells to the extracellular matrix. Biosens Bioelectron. 2008;23:1390-6 pubmed publisher
Abraham L, Dice J, Lee K, Kaplan D. Phagocytosis and remodeling of collagen matrices. Exp Cell Res. 2007;313:1045-55 pubmed
Saunders W, Bohnsack B, Faske J, Anthis N, Bayless K, Hirschi K, et al. Coregulation of vascular tube stabilization by endothelial cell TIMP-2 and pericyte TIMP-3. J Cell Biol. 2006;175:179-91 pubmed
Goda S, Inoue H, Umehara H, Miyaji M, Nagano Y, Harakawa N, et al. Matrix metalloproteinase-1 produced by human CXCL12-stimulated natural killer cells. Am J Pathol. 2006;169:445-58 pubmed
Bix G, Fu J, Gonzalez E, Macro L, Barker A, Campbell S, et al. Endorepellin causes endothelial cell disassembly of actin cytoskeleton and focal adhesions through alpha2beta1 integrin. J Cell Biol. 2004;166:97-109 pubmed
Nesbitt W, Giuliano S, Kulkarni S, Dopheide S, Harper I, Jackson S. Intercellular calcium communication regulates platelet aggregation and thrombus growth. J Cell Biol. 2003;160:1151-61 pubmed
product information
Catalog Number :
MAB1998Z
Subcategory :
Cell Structure
Product Name :
Anti-Integrin α2β1 Antibody, clone BHA2.1, azide free
Product Type :
Antibodies
Clonality :
Monoclonal Antibody
Gene ID :
P17301
Host Name :
Mouse
Antigen :
Integrin α2β1
Clone :
BHA2.1
Conjugate :
Purified
Isotype :
IgG1κ
Product Description :
Anti-Integrin α2β1 Antibody, clone BHA2.1, azide free
Cross Reactivity :
Human;Pig
ALT Names :
VLA-2;MAB1998
Specificity :
Reacts with the collagen receptor VLA-2 (alpha2beta1) integrin complex.
Package Size :
100 μg
Uses :
Flow Cytometry;Immunohistochemistry;Immunoprecipitation;Affects Function
Storage :
Maintain for 1 year at 2–8°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
company information
EMD Millipore
290 Concord Road
Billerica, Massachusetts 01821
bioscienceshelp@emdchemical.com
https://www.emdmillipore.com
888-854-3417
headquarters: United States
EMD Millipore is the Life Science division of Merck KGaA of Darmstadt, Germany

Hundreds of New Antibodies in the areas of:
  • • Cancer
  • • Nuclear Signaling
  • • Apoptosis
  • • Cardiovascular Disease
  • • Developmental Biology
  • • Metabolic Disease
  • • Neurodegenerative Disease
  • • Cell Biology
View all the new antibodies at www.emdmillipore.com.