| Published Application/Species/Sample/Dilution | Reference |
|---|
- immunohistochemistry - frozen section; mouse; 1:200; loading ...; fig s3a, s3f
| Henning C, Branopolski A, Schuler D, Dimitroulis D, Huelsemann P, Nicolaus C, et al. Requirement of β1 integrin for endothelium-dependent vasodilation and collateral formation in hindlimb ischemia. Sci Rep. 2019;9:16931 pubmed publisher |
- immunohistochemistry; mouse; loading ...; fig s6a
| Xanthis I, Souilhol C, Serbanovic Canic J, Roddie H, Kalli A, Fragiadaki M, et al. β1 integrin is a sensor of blood flow direction. J Cell Sci. 2019;132: pubmed publisher |
- immunohistochemistry - paraffin section; mouse; loading ...; fig 3a
| Urner S, Planas Paz L, Hilger L, Henning C, Branopolski A, Kelly Goss M, et al. Identification of ILK as a critical regulator of VEGFR3 signalling and lymphatic vascular growth. EMBO J. 2019;38: pubmed publisher |
- immunohistochemistry - frozen section; mouse; loading ...; fig 3a
| Natsumi A, Sugawara K, Yasumizu M, Mizukami Y, Sano S, Morita A, et al. Re-investigating the Basement Membrane Zone of Psoriatic Epidermal Lesions: Is Laminin-511 a New Player in Psoriasis Pathogenesis?. J Histochem Cytochem. 2018;66:847-862 pubmed publisher |
- immunohistochemistry - frozen section; mouse; loading ...; fig 3c
| Yui S, Azzolin L, Maimets M, Pedersen M, Fordham R, Hansen S, et al. YAP/TAZ-Dependent Reprogramming of Colonic Epithelium Links ECM Remodeling to Tissue Regeneration. Cell Stem Cell. 2018;22:35-49.e7 pubmed publisher |
- immunohistochemistry; mouse; loading ...; fig s3m
| Guimarães Camboa N, Cattaneo P, Sun Y, Moore Morris T, Gu Y, Dalton N, et al. Pericytes of Multiple Organs Do Not Behave as Mesenchymal Stem Cells In Vivo. Cell Stem Cell. 2017;20:345-359.e5 pubmed publisher |
- immunohistochemistry; mouse; 1:100; loading ...; fig s1d
| Scully K, Skowronska Krawczyk D, Krawczyk M, Merkurjev D, Taylor H, Livolsi A, et al. Epithelial cell integrin β1 is required for developmental angiogenesis in the pituitary gland. Proc Natl Acad Sci U S A. 2016;113:13408-13413 pubmed |
- western blot; mouse; loading ...; fig 4a
| Gómez Salinero J, López Olañeta M, Ortiz Sánchez P, Larrasa Alonso J, Gatto A, Felkin L, et al. The Calcineurin Variant CnA?1 Controls Mouse Embryonic Stem Cell Differentiation by Directing mTORC2 Membrane Localization and Activation. Cell Chem Biol. 2016;23:1372-1382 pubmed publisher |
- immunohistochemistry; mouse; 1:200; fig 1
- western blot; mouse; 1:1000; fig 1
| Martin K, Pritchett J, Llewellyn J, Mullan A, Athwal V, Dobie R, et al. PAK proteins and YAP-1 signalling downstream of integrin beta-1 in myofibroblasts promote liver fibrosis. Nat Commun. 2016;7:12502 pubmed publisher |
- immunohistochemistry - frozen section; mouse; 1:500; fig 1s2
| Ju X, Hou Q, Sheng A, Wu K, Zhou Y, Jin Y, et al. The hominoid-specific gene TBC1D3 promotes generation of basal neural progenitors and induces cortical folding in mice. elife. 2016;5: pubmed publisher |
- western blot; mouse; loading ...; fig 5f
| Sens C, Altrock E, Rau K, Klemis V, von Au A, Pettera S, et al. An O-Glycosylation of Fibronectin Mediates Hepatic Osteodystrophy Through α4β1 Integrin. J Bone Miner Res. 2017;32:70-81 pubmed publisher |
- western blot; mouse; 1:1000; fig s1d
| Rozo M, Li L, Fan C. Targeting ?1-integrin signaling enhances regeneration in aged and dystrophic muscle in mice. Nat Med. 2016;22:889-96 pubmed publisher |
- immunoprecipitation; mouse; fig 6
| Barrow McGee R, Kishi N, Joffre C, Ménard L, Hervieu A, Bakhouche B, et al. Beta 1-integrin-c-Met cooperation reveals an inside-in survival signalling on autophagy-related endomembranes. Nat Commun. 2016;7:11942 pubmed publisher |
- immunohistochemistry; Neisseria gonorrhoeae; 1:200; fig 4
| Shah B, Lutter D, Bochenek M, Kato K, Tsytsyura Y, Glyvuk N, et al. C3G/Rapgef1 Is Required in Multipolar Neurons for the Transition to a Bipolar Morphology during Cortical Development. PLoS ONE. 2016;11:e0154174 pubmed publisher |
- western blot; rat; 1:1000; fig 2
| Lauterborn J, Kramar E, Rice J, Babayan A, Cox C, Karsten C, et al. Cofilin Activation Is Temporally Associated with the Cessation of Growth in the Developing Hippocampus. Cereb Cortex. 2017;27:2640-2651 pubmed publisher |
- immunocytochemistry; mouse; 1:1000; fig 5
| Nishioka T, Arima N, Kano K, Hama K, Itai E, Yukiura H, et al. ATX-LPA1 axis contributes to proliferation of chondrocytes by regulating fibronectin assembly leading to proper cartilage formation. Sci Rep. 2016;6:23433 pubmed publisher |
- flow cytometry; mouse; 1:400; fig 1s2
| Theodosiou M, Widmaier M, Böttcher R, Rognoni E, Veelders M, Bharadwaj M, et al. Kindlin-2 cooperates with talin to activate integrins and induces cell spreading by directly binding paxillin. elife. 2016;5:e10130 pubmed publisher |
- immunohistochemistry; mouse; 1:200; fig 6
- western blot; mouse; 1:1000; fig 6
| Zhang Y, Fan J, Ho J, Hu T, Kneeland S, Fan X, et al. Crim1 regulates integrin signaling in murine lens development. Development. 2016;143:356-66 pubmed publisher |
- flow cytometry; human; 1:400; fig 4
| Austen K, Ringer P, Mehlich A, Chrostek Grashoff A, Kluger C, Klingner C, et al. Extracellular rigidity sensing by talin isoform-specific mechanical linkages. Nat Cell Biol. 2015;17:1597-606 pubmed publisher |
- immunohistochemistry - paraffin section; mouse; 1:100; fig 6
| Xu J, Wan P, Wang M, Zhang J, Gao X, Hu B, et al. AIP1-mediated actin disassembly is required for postnatal germ cell migration and spermatogonial stem cell niche establishment. Cell Death Dis. 2015;6:e1818 pubmed publisher |
- immunohistochemistry; mouse; 1:100
| Gonzalez S, Fernando R, Berthelot J, Perrin Tricaud C, Sarzi E, Chrast R, et al. In vivo time-lapse imaging of mitochondria in healthy and diseased peripheral myelin sheath. Mitochondrion. 2015;23:32-41 pubmed publisher |
- immunoprecipitation; mouse; fig 9
| Yazlovitskaya E, Tseng H, Viquez O, Tu T, Mernaugh G, McKee K, et al. Integrin α3β1 regulates kidney collecting duct development via TRAF6-dependent K63-linked polyubiquitination of Akt. Mol Biol Cell. 2015;26:1857-74 pubmed publisher |
- immunohistochemistry; mouse; 1:250; fig 1
| Plosa E, Young L, Gulleman P, Polosukhin V, Zaynagetdinov R, Benjamin J, et al. Epithelial β1 integrin is required for lung branching morphogenesis and alveolarization. Development. 2014;141:4751-62 pubmed publisher |
- immunocytochemistry; mouse; fig 8
- western blot; mouse; fig 3
| Tseng H, Thorausch N, Ziegler T, Meves A, Fassler R, Böttcher R. Sorting nexin 31 binds multiple ? integrin cytoplasmic domains and regulates ?1 integrin surface levels and stability. J Mol Biol. 2014;426:3180-3194 pubmed publisher |
- immunohistochemistry - frozen section; mouse; 1:100
| Scheiblin D, Gao J, Caplan J, Simirskii V, Czymmek K, Mathias R, et al. Beta-1 integrin is important for the structural maintenance and homeostasis of differentiating fiber cells. Int J Biochem Cell Biol. 2014;50:132-45 pubmed publisher |
- immunohistochemistry; mouse
| Hu J, Lu J, Lian G, Zhang J, Hecht J, Sheen V. Filamin B regulates chondrocyte proliferation and differentiation through Cdk1 signaling. PLoS ONE. 2014;9:e89352 pubmed publisher |
- immunoprecipitation; human
- immunohistochemistry; human
| Diaferia G, Cirulli V, Biunno I. SEL1L regulates adhesion, proliferation and secretion of insulin by affecting integrin signaling. PLoS ONE. 2013;8:e79458 pubmed publisher |
- immunohistochemistry; mouse; fig 2
| Cagnet S, Faraldo M, Kreft M, Sonnenberg A, Raymond K, Glukhova M. Signaling events mediated by ?3?1 integrin are essential for mammary tumorigenesis. Oncogene. 2014;33:4286-95 pubmed publisher |
| Nilsson D, Heglind M, Arani Z, Enerback S. Foxc2 is essential for podocyte function. Physiol Rep. 2019;7:e14083 pubmed publisher |
| Poitelon Y, Matafora V, Silvestri N, Zambroni D, McGarry C, Serghany N, et al. A dual role for Integrin α6β4 in modulating hereditary neuropathy with liability to pressure palsies. J Neurochem. 2018;145:245-257 pubmed publisher |
| Raven A, Lu W, Man T, Ferreira Gonzalez S, O Duibhir E, Dwyer B, et al. Cholangiocytes act as facultative liver stem cells during impaired hepatocyte regeneration. Nature. 2017;547:350-354 pubmed publisher |
| Georgiadou M, Lilja J, Jacquemet G, Guzmán C, Rafaeva M, Alibert C, et al. AMPK negatively regulates tensin-dependent integrin activity. J Cell Biol. 2017;216:1107-1121 pubmed publisher |
| Vanhoutte D, Schips T, Kwong J, Davis J, Tjondrokoesoemo A, Brody M, et al. Thrombospondin expression in myofibers stabilizes muscle membranes. elife. 2016;5: pubmed publisher |
| Lu N, Karlsen T, Reed R, Kusche Gullberg M, Gullberg D. Fibroblast ?11?1 integrin regulates tensional homeostasis in fibroblast/A549 carcinoma heterospheroids. PLoS ONE. 2014;9:e103173 pubmed publisher |
| Löffek S, Hurskainen T, Jackow J, Sigloch F, Schilling O, Tasanen K, et al. Transmembrane collagen XVII modulates integrin dependent keratinocyte migration via PI3K/Rac1 signaling. PLoS ONE. 2014;9:e87263 pubmed publisher |
| Mamuya F, Wang Y, Roop V, Scheiblin D, Zajac J, Duncan M. The roles of ?V integrins in lens EMT and posterior capsular opacification. J Cell Mol Med. 2014;18:656-70 pubmed publisher |
| Meves A, Stremmel C, Böttcher R, Fassler R. ?1 integrins with individually disrupted cytoplasmic NPxY motifs are embryonic lethal but partially active in the epidermis. J Invest Dermatol. 2013;133:2722-2731 pubmed publisher |
| Huang J, Arsenault M, Kann M, Lopez Mendez C, Saleh M, Wadowska D, et al. The transcription factor Sry-related HMG box-4 (SOX4) is required for normal renal development in vivo. Dev Dyn. 2013;242:790-9 pubmed publisher |
| Rey Barroso J, Colo G, Alvarez Barrientos A, Redondo Muñoz J, Carvajal Gonzalez J, Mulero Navarro S, et al. The dioxin receptor controls ?1 integrin activation in fibroblasts through a Cbp-Csk-Src pathway. Cell Signal. 2013;25:848-59 pubmed publisher |
| Hägerling R, Pollmann C, Andreas M, Schmidt C, Nurmi H, Adams R, et al. A novel multistep mechanism for initial lymphangiogenesis in mouse embryos based on ultramicroscopy. EMBO J. 2013;32:629-44 pubmed publisher |
| Boulter E, Estrach S, Errante A, Pons C, Cailleteau L, Tissot F, et al. CD98hc (SLC3A2) regulation of skin homeostasis wanes with age. J Exp Med. 2013;210:173-90 pubmed publisher |
| Chen J, Krasnow M. Integrin Beta 1 suppresses multilayering of a simple epithelium. PLoS ONE. 2012;7:e52886 pubmed publisher |
| Ma S, Kwon H, Huang Z. Ric-8a, a guanine nucleotide exchange factor for heterotrimeric G proteins, regulates bergmann glia-basement membrane adhesion during cerebellar foliation. J Neurosci. 2012;32:14979-93 pubmed publisher |
| Moran Jones K, Ledger A, Naylor M. ?1 integrin deletion enhances progression of prostate cancer in the TRAMP mouse model. Sci Rep. 2012;2:526 pubmed publisher |
| Ohmura T, Shioi G, Hirano M, Aizawa S. Neural tube defects by NUAK1 and NUAK2 double mutation. Dev Dyn. 2012;241:1350-64 pubmed publisher |
| Linford A, Yoshimura S, Nunes Bastos R, Langemeyer L, Gerondopoulos A, Rigden D, et al. Rab14 and its exchange factor FAM116 link endocytic recycling and adherens junction stability in migrating cells. Dev Cell. 2012;22:952-66 pubmed publisher |
| Jeanes A, Wang P, Moreno Layseca P, Paul N, Cheung J, Tsang R, et al. Specific ?-containing integrins exert differential control on proliferation and two-dimensional collective cell migration in mammary epithelial cells. J Biol Chem. 2012;287:24103-12 pubmed publisher |
| Romano R, Smalley K, Magraw C, Serna V, Kurita T, Raghavan S, et al. ΔNp63 knockout mice reveal its indispensable role as a master regulator of epithelial development and differentiation. Development. 2012;139:772-82 pubmed publisher |
| Campbell J, Davidenko N, Caffarel M, Cameron R, Watson C. A multifunctional 3D co-culture system for studies of mammary tissue morphogenesis and stem cell biology. PLoS ONE. 2011;6:e25661 pubmed publisher |
| Jung G, Park Y, Han J. Mediation of Rac1 activation by kindlin-2: an essential function in osteoblast adhesion, spreading, and proliferation. J Cell Biochem. 2011;112:2541-8 pubmed publisher |
| De Wever O, Sobczak Thepot J, Vercoutter Edouart A, Michalski J, Ouelaa Benslama R, Stupack D, et al. Priming and potentiation of DNA damage response by fibronectin in human colon cancer cells and tumor-derived myofibroblasts. Int J Oncol. 2011;39:393-400 pubmed publisher |
| Gu Z, Noss E, Hsu V, Brenner M. Integrins traffic rapidly via circular dorsal ruffles and macropinocytosis during stimulated cell migration. J Cell Biol. 2011;193:61-70 pubmed publisher |
| Hsueh Y, Chen H, Chu W, Cheng C, Kuo P, Lin L, et al. STAT3 regulates the proliferation and differentiation of rabbit limbal epithelial cells via a ?Np63-dependent mechanism. Invest Ophthalmol Vis Sci. 2011;52:4685-93 pubmed publisher |
| Kusuma N, Denoyer D, Eble J, Redvers R, Parker B, Pelzer R, et al. Integrin-dependent response to laminin-511 regulates breast tumor cell invasion and metastasis. Int J Cancer. 2012;130:555-66 pubmed publisher |
| Zhu H, Riau A, Beuerman R. Epithelial microfilament regulators show regional distribution in mouse conjunctiva. Mol Vis. 2010;16:2215-24 pubmed |
| DeRouen M, Zhen H, Tan S, Williams S, Marinkovich M, Oro A. Laminin-511 and integrin beta-1 in hair follicle development and basal cell carcinoma formation. BMC Dev Biol. 2010;10:112 pubmed publisher |
| Niculescu C, Ganguli Indra G, Pfister V, Dupé V, Messaddeq N, De Arcangelis A, et al. Conditional ablation of integrin alpha-6 in mouse epidermis leads to skin fragility and inflammation. Eur J Cell Biol. 2011;90:270-7 pubmed publisher |
| Destaing O, Planus E, Bouvard D, Oddou C, Badowski C, Bossy V, et al. ?1A integrin is a master regulator of invadosome organization and function. Mol Biol Cell. 2010;21:4108-19 pubmed publisher |
| Moriguchi H, Chung R, Mihara M, Sato C. Generation of human induced pluripotent stem cells from liver progenitor cells by only small molecules. Hepatology. 2010;52:1169; author reply 1169-70 pubmed publisher |
| Ren K, Fourel L, Rouvière C, Albiges Rizo C, Picart C. Manipulation of the adhesive behaviour of skeletal muscle cells on soft and stiff polyelectrolyte multilayers. Acta Biomater. 2010;6:4238-48 pubmed publisher |
| Ozcelik M, Cotter L, Jacob C, Pereira J, Relvas J, Suter U, et al. Pals1 is a major regulator of the epithelial-like polarization and the extension of the myelin sheath in peripheral nerves. J Neurosci. 2010;30:4120-31 pubmed publisher |
| Makwana M, Werner A, Acosta Saltos A, Gonitel R, Pararajasingam A, Pararajasingham A, et al. Peripheral facial nerve axotomy in mice causes sprouting of motor axons into perineuronal central white matter: time course and molecular characterization. J Comp Neurol. 2010;518:699-721 pubmed publisher |
| Mizrak S, Chikhovskaya J, Sadri Ardekani H, van Daalen S, Korver C, Hovingh S, et al. Embryonic stem cell-like cells derived from adult human testis. Hum Reprod. 2010;25:158-67 pubmed publisher |
| Barros C, Nguyen T, Spencer K, Nishiyama A, Colognato H, Muller U. Beta1 integrins are required for normal CNS myelination and promote AKT-dependent myelin outgrowth. Development. 2009;136:2717-24 pubmed publisher |
| Raducanu A, Hunziker E, Drosse I, Aszodi A. Beta1 integrin deficiency results in multiple abnormalities of the knee joint. J Biol Chem. 2009;284:23780-92 pubmed publisher |
| Matsuyama M, Aizawa S, Shimono A. Sfrp controls apicobasal polarity and oriented cell division in developing gut epithelium. PLoS Genet. 2009;5:e1000427 pubmed publisher |
| Bruggeman S, Hulsman D, Van Lohuizen M. Bmi1 deficient neural stem cells have increased integrin dependent adhesion to self-secreted matrix. Biochim Biophys Acta. 2009;1790:351-60 pubmed publisher |
| Michael K, Dumbauld D, Burns K, Hanks S, Garcia A. Focal adhesion kinase modulates cell adhesion strengthening via integrin activation. Mol Biol Cell. 2009;20:2508-19 pubmed publisher |
| Oikawa T, Takenawa T. PtdIns(3,4)P2 instigates focal adhesions to generate podosomes. Cell Adh Migr. 2009;3:195-7 pubmed |
| Nishimune H, Valdez G, Jarad G, Moulson C, Muller U, Miner J, et al. Laminins promote postsynaptic maturation by an autocrine mechanism at the neuromuscular junction. J Cell Biol. 2008;182:1201-15 pubmed publisher |
| Young Pearse T, Chen A, Chang R, Marquez C, Selkoe D. Secreted APP regulates the function of full-length APP in neurite outgrowth through interaction with integrin beta1. Neural Dev. 2008;3:15 pubmed publisher |
| Goetz J, Joshi B, Lajoie P, Strugnell S, Scudamore T, Kojic L, et al. Concerted regulation of focal adhesion dynamics by galectin-3 and tyrosine-phosphorylated caveolin-1. J Cell Biol. 2008;180:1261-75 pubmed publisher |
| Pozzi A, Jarad G, Moeckel G, Coffa S, Zhang X, Gewin L, et al. Beta1 integrin expression by podocytes is required to maintain glomerular structural integrity. Dev Biol. 2008;316:288-301 pubmed publisher |
| Maginnis M, Mainou B, Derdowski A, Johnson E, Zent R, Dermody T. NPXY motifs in the beta1 integrin cytoplasmic tail are required for functional reovirus entry. J Virol. 2008;82:3181-91 pubmed publisher |
| Lathia J, Patton B, Eckley D, Magnus T, Mughal M, Sasaki T, et al. Patterns of laminins and integrins in the embryonic ventricular zone of the CNS. J Comp Neurol. 2007;505:630-43 pubmed |
| Lluri G, Langlois G, Soloway P, Jaworski D. Tissue inhibitor of metalloproteinase-2 (TIMP-2) regulates myogenesis and beta1 integrin expression in vitro. Exp Cell Res. 2008;314:11-24 pubmed |
| Simirskii V, Wang Y, Duncan M. Conditional deletion of beta1-integrin from the developing lens leads to loss of the lens epithelial phenotype. Dev Biol. 2007;306:658-68 pubmed |
| Jovic M, Naslavsky N, Rapaport D, Horowitz M, Caplan S. EHD1 regulates beta1 integrin endosomal transport: effects on focal adhesions, cell spreading and migration. J Cell Sci. 2007;120:802-14 pubmed |
| Lagana A, Goetz J, Cheung P, Raz A, Dennis J, Nabi I. Galectin binding to Mgat5-modified N-glycans regulates fibronectin matrix remodeling in tumor cells. Mol Cell Biol. 2006;26:3181-93 pubmed |
| Maginnis M, Forrest J, Kopecky Bromberg S, Dickeson S, Santoro S, Zutter M, et al. Beta1 integrin mediates internalization of mammalian reovirus. J Virol. 2006;80:2760-70 pubmed |
| Kuo J, Wang W, Yao C, Wu P, Chen R. The tumor suppressor DAPK inhibits cell motility by blocking the integrin-mediated polarity pathway. J Cell Biol. 2006;172:619-31 pubmed |
| Zanet J, Pibre S, Jacquet C, Ramirez A, de Alboran I, Gandarillas A. Endogenous Myc controls mammalian epidermal cell size, hyperproliferation, endoreplication and stem cell amplification. J Cell Sci. 2005;118:1693-704 pubmed |
