Integrin α2 Antibody, clone 10G11 | EMD Millipore MAB1988 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Integrin α2 Antibody, clone 10G11

catalog :

MAB1988

quantity :

100 µg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

10G11

reactivity :

human

application :

immunohistochemistry, blocking or activating experiments

citations: 7

Published Application/Species/Sample/Dilution	Reference
blocking or activating experiments; human; fig 3	Artym V, Swatkoski S, Matsumoto K, Campbell C, Petrie R, Dimitriadis E, et al. Dense fibrillar collagen is a potent inducer of invadopodia via a specific signaling network. J Cell Biol. 2015;208:331-50 pubmed publisher
blocking or activating experiments; human	Damiano L, Stewart K, Cohet N, Mouw J, Lakins J, Debnath J, et al. Oncogenic targeting of BRM drives malignancy through C/EBP?-dependent induction of ?5 integrin. Oncogene. 2014;33:2441-53 pubmed publisher
	Miroshnikova Y, Rozenberg G, Cassereau L, Pickup M, Mouw J, Ou G, et al. ?5?1-Integrin promotes tension-dependent mammary epithelial cell invasion by engaging the fibronectin synergy site. Mol Biol Cell. 2017;28:2958-2977 pubmed publisher
	Prusty A, Meduri R, Prusty B, Vanselow J, Schlosser A, Fischer U. Impaired spliceosomal UsnRNP assembly leads to Sm mRNA down-regulation and Sm protein degradation. J Cell Biol. 2017;216:2391-2407 pubmed publisher
	Stejskalova E, Stanek D. The splicing factor U1-70K interacts with the SMN complex and is required for nuclear gem integrity. J Cell Sci. 2014;127:3909-15 pubmed publisher
	Kirino Y, Kim N, De Planell Saguer M, Khandros E, Chiorean S, Klein P, et al. Arginine methylation of Piwi proteins catalysed by dPRMT5 is required for Ago3 and Aub stability. Nat Cell Biol. 2009;11:652-8 pubmed publisher
	Zahir N, Lakins J, Russell A, Ming W, Chatterjee C, Rozenberg G, et al. Autocrine laminin-5 ligates alpha6beta4 integrin and activates RAC and NFkappaB to mediate anchorage-independent survival of mammary tumors. J Cell Biol. 2003;163:1397-407 pubmed

product information

Catalog Number :

MAB1988

Subcategory :

Cell Structure

Product Name :

Anti-Integrin α2 Antibody, clone 10G11

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P17301

Host Name :

Mouse

Antigen :

Integrin α2

Clone :

10G11

Conjugate :

Purified

Isotype :

IgG1

Product Description :

Anti-Integrin α2 Antibody, clone 10G11

Cross Reactivity :

Human

ALT Names :

CD49b,VLA-2, CLB-tromb/4

Immunogen :

Human T lymphocytes

Specificity :

Directed against the a2 human integrin (CD49b antigen, GPIa or VLA-2 alpha chain), which can form distinct complexes with the CD29-antigen (GPIIa or VLA beta-chain), resulting in the VLA-2 complex which is expressed on human platelets. Reacts with platelets, long-term cultivated T lymphocytes and activated T lymphocytes. In immunohistology it reacts with thymocytes, epithelial cells of a variety of tissues, peripheral nerves, fibroblasts, osteoclasts, glomerular mesangium and most non-hematopoietic adherent cell lines.

Package Size :

100 µg

Uses :

Immunohistochemistry;Affects Function

Storage :

Maintain at 2-8°C in undiluted aliquots for up to 12 months from date of receipt.