| Published Application/Species/Sample/Dilution | Reference |
|---|
- blocking or activating experiments; human; 2.5 ug/ml; loading ...; fig 3a, 6a
| Wang S, Zhang Q, Tiwari S, Lichinchi G, Yau E, Hui H, et al. Integrin αvβ5 Internalizes Zika Virus during Neural Stem Cells Infection and Provides a Promising Target for Antiviral Therapy. Cell Rep. 2020;30:969-983.e4 pubmed publisher |
- flow cytometry; human; fig 1
| Sugahara K, Braun G, de Mendoza T, Kotamraju V, French R, Lowy A, et al. Tumor-penetrating iRGD peptide inhibits metastasis. Mol Cancer Ther. 2015;14:120-8 pubmed publisher |
- flow cytometry; human
- immunocytochemistry; human
| Horiguchi H, Endo M, Miyamoto Y, Sakamoto Y, Odagiri H, Masuda T, et al. Angiopoietin-like protein 2 renders colorectal cancer cells resistant to chemotherapy by activating spleen tyrosine kinase-phosphoinositide 3-kinase-dependent anti-apoptotic signaling. Cancer Sci. 2014;105:1550-9 pubmed publisher |
- blocking or activating experiments; human
| Chen M, Zhang Y, Yu V, Chong Y, Yoshioka T, Ge R. Isthmin targets cell-surface GRP78 and triggers apoptosis via induction of mitochondrial dysfunction. Cell Death Differ. 2014;21:797-810 pubmed publisher |
| Bianchi Smiraglia A, Kunnev D, Limoge M, Lee A, Beckerle M, Bakin A. Integrin-?5 and zyxin mediate formation of ventral stress fibers in response to transforming growth factor ?. Cell Cycle. 2013;12:3377-89 pubmed publisher |
- blocking or activating experiments; human
- flow cytometry; human
| Tibaldi L, Leyman S, Nicolas A, Notebaert S, Dewulf M, Ngo T, et al. New blocking antibodies impede adhesion, migration and survival of ovarian cancer cells, highlighting MFGE8 as a potential therapeutic target of human ovarian carcinoma. PLoS ONE. 2013;8:e72708 pubmed publisher |
- blocking or activating experiments; human; 20 ug/ml
| Azab W, Lehmann M, Osterrieder N. Glycoprotein H and ?4?1 integrins determine the entry pathway of alphaherpesviruses. J Virol. 2013;87:5937-48 pubmed publisher |
| Jiang X, Teng M, Guo X, Zhang D, Zhang Q, Zhang J, et al. Switch from αvβ5 to αvβ6 integrin is required for CD9-regulated keratinocyte migration and MMP-9 activation. FEBS Lett. 2014;588:4044-52 pubmed publisher |
| Hsiao C, Wang W, Kuo W, Chen H, Chen T, Hamann J, et al. CD97 inhibits cell migration in human fibrosarcoma cells by modulating TIMP-2/MT1- MMP/MMP-2 activity--role of GPS autoproteolysis and functional cooperation between the N- and C-terminal fragments. FEBS J. 2014;281:4878-91 pubmed publisher |
| Zhan Y, Yu B, Wang Z, Zhang Y, Zhang H, Wu H, et al. A fiber-modified adenovirus co-expressing HSV-TK and Coli.NTR enhances antitumor activities in breast cancer cells. Int J Clin Exp Pathol. 2014;7:2850-60 pubmed |
| Kim B, Jang I, Shin S, Kwon Y, Heo S, Choi E, et al. Therapeutic angiogenesis in a murine model of limb ischemia by recombinant periostin and its fasciclin I domain. Biochim Biophys Acta. 2014;1842:1324-32 pubmed publisher |
| Ray A, Schaffner F, Janouskova H, Noulet F, Rognan D, Lelong Rebel I, et al. Single cell tracking assay reveals an opposite effect of selective small non-peptidic ?5?1 or ?v?3/?5 integrin antagonists in U87MG glioma cells. Biochim Biophys Acta. 2014;1840:2978-87 pubmed publisher |
| Wei Y, Zhang Y, Cai H, Mirza A, Iorio R, Peeples M, et al. Roles of the putative integrin-binding motif of the human metapneumovirus fusion (f) protein in cell-cell fusion, viral infectivity, and pathogenesis. J Virol. 2014;88:4338-52 pubmed publisher |
| Rapraeger A, Ell B, Roy M, Li X, Morrison O, Thomas G, et al. Vascular endothelial-cadherin stimulates syndecan-1-coupled insulin-like growth factor-1 receptor and cross-talk between ?V?3 integrin and vascular endothelial growth factor receptor 2 at the onset of endothelial cell dissemination during angiogenesi. FEBS J. 2013;280:2194-206 pubmed publisher |
| Majhen D, Richardson J, Vukelić B, Dodig I, Cindric M, Benihoud K, et al. The disulfide bond of an RGD4C motif inserted within the Hi loop of the adenovirus type 5 fiber protein is critical for retargeting to ?v -integrins. J Gene Med. 2012;14:788-97 pubmed publisher |
| Canonici A, Pellegrino E, Siret C, Terciolo C, Czerucka D, Bastonero S, et al. Saccharomyces boulardii improves intestinal epithelial cell restitution by inhibiting ?v?5 integrin activation state. PLoS ONE. 2012;7:e45047 pubmed publisher |
| Westenskow P, Moreno S, Krohne T, Kurihara T, Zhu S, Zhang Z, et al. Using flow cytometry to compare the dynamics of photoreceptor outer segment phagocytosis in iPS-derived RPE cells. Invest Ophthalmol Vis Sci. 2012;53:6282-90 pubmed publisher |
| Bianchi Smiraglia A, Paesante S, Bakin A. Integrin ?5 contributes to the tumorigenic potential of breast cancer cells through the Src-FAK and MEK-ERK signaling pathways. Oncogene. 2013;32:3049-58 pubmed publisher |
| Jandova J, Beyer T, Meuillet E, Watts G. The matrix protein CCN1/CYR61 is required for ?(V)?5-mediated cancer cell migration. Cell Biochem Funct. 2012;30:687-95 pubmed publisher |
| Kim S, Park S, Kim S, Bae D, Pyo J, Hong M, et al. Cross talk between engulfment receptors stabilin-2 and integrin ?v?5 orchestrates engulfment of phosphatidylserine-exposed erythrocytes. Mol Cell Biol. 2012;32:2698-708 pubmed publisher |
| Hung W, Huang K, Wu C, Chi C, Kao H, Li A, et al. Mitochondrial dysfunction promotes cell migration via reactive oxygen species-enhanced ?5-integrin expression in human gastric cancer SC-M1 cells. Biochim Biophys Acta. 2012;1820:1102-10 pubmed publisher |
| Bzowska M, Nogieć A, Skrzeczyńska Moncznik J, Mickowska B, Guzik K, Pryjma J. Oxidized LDLs inhibit TLR-induced IL-10 production by monocytes: a new aspect of pathogen-accelerated atherosclerosis. Inflammation. 2012;35:1567-84 pubmed publisher |
| Edkins A, Borland G, Acharya M, Cogdell R, Ozanne B, Cushley W. Differential regulation of monocyte cytokine release by ?V and ?(2) integrins that bind CD23. Immunology. 2012;136:241-51 pubmed publisher |
| Wiedemann T, Hofbaur S, Tegtmeyer N, Huber S, Sewald N, Wessler S, et al. Helicobacter pylori CagL dependent induction of gastrin expression via a novel ?v?5-integrin-integrin linked kinase signalling complex. Gut. 2012;61:986-96 pubmed publisher |
| Haseley A, Boone S, Wojton J, Yu L, Yoo J, Yu J, et al. Extracellular matrix protein CCN1 limits oncolytic efficacy in glioma. Cancer Res. 2012;72:1353-62 pubmed publisher |
| Azab W, Osterrieder N. Glycoproteins D of equine herpesvirus type 1 (EHV-1) and EHV-4 determine cellular tropism independently of integrins. J Virol. 2012;86:2031-44 pubmed publisher |
| Qin S, Rodrigues G. Roles of ?v?5, FAK and MerTK in oxidative stress inhibition of RPE cell phagocytosis. Exp Eye Res. 2012;94:63-70 pubmed publisher |
| Borovjagin A, Dong J, Passineau M, Ren C, Lamani E, Mamaeva O, et al. Adenovirus gene transfer to amelogenesis imperfecta ameloblast-like cells. PLoS ONE. 2011;6:e24281 pubmed publisher |
| Huang C, Zhang J, Ao M, Li Y, Zhang C, Xu Y, et al. Combination of retinal pigment epithelium cell-conditioned medium and photoreceptor outer segments stimulate mesenchymal stem cell differentiation toward a functional retinal pigment epithelium cell phenotype. J Cell Biochem. 2012;113:590-8 pubmed publisher |
| Conradi J, Huber S, Gaus K, Mertink F, Royo Gracia S, Strijowski U, et al. Cyclic RGD peptides interfere with binding of the Helicobacter pylori protein CagL to integrins ?V?3 and ?5?1. Amino Acids. 2012;43:219-32 pubmed publisher |
| Tan T, Huang Y, Chang J, Lin J, Fong Y, Kuo C, et al. CCN3 increases BMP-4 expression and bone mineralization in osteoblasts. J Cell Physiol. 2012;227:2531-41 pubmed publisher |
| Shannon Lowe C, Rowe M. Epstein-Barr virus infection of polarized epithelial cells via the basolateral surface by memory B cell-mediated transfer infection. PLoS Pathog. 2011;7:e1001338 pubmed publisher |
| Zhang Y, Chen M, Venugopal S, Zhou Y, Xiang W, Li Y, et al. Isthmin exerts pro-survival and death-promoting effect on endothelial cells through alphavbeta5 integrin depending on its physical state. Cell Death Dis. 2011;2:e153 pubmed publisher |
| Grzesiak J, Tran Cao H, Burton D, Kaushal S, Vargas F, Clopton P, et al. Knockdown of the ?(1) integrin subunit reduces primary tumor growth and inhibits pancreatic cancer metastasis. Int J Cancer. 2011;129:2905-15 pubmed publisher |
| Fukui N, Ikeda Y, Tanaka N, Wake M, Yamaguchi T, Mitomi H, et al. ?v?5 integrin promotes dedifferentiation of monolayer-cultured articular chondrocytes. Arthritis Rheum. 2011;63:1938-49 pubmed publisher |
| Metzner C, Raupach C, Mierke C, Fabry B. Fluctuations of cytoskeleton-bound microbeads--the effect of bead-receptor binding dynamics. J Phys Condens Matter. 2010;22:194105 pubmed publisher |
| Chuang J, Yang W, Lai C, Lin C, Tsai M, Tang C. CTGF inhibits cell motility and COX-2 expression in oral cancer cells. Int Immunopharmacol. 2011;11:948-54 pubmed publisher |
| Desai R, Khan M, Gopal S, Chen C. Subcellular spatial segregation of integrin subtypes by patterned multicomponent surfaces. Integr Biol (Camb). 2011;3:560-7 pubmed publisher |
| Hsiao C, Chen H, Chang G, Lin H. GPS autoproteolysis is required for CD97 to up-regulate the expression of N-cadherin that promotes homotypic cell-cell aggregation. FEBS Lett. 2011;585:313-8 pubmed publisher |
| de Vrij J, Van Den Hengel S, Uil T, Koppers Lalic D, Dautzenberg I, Stassen O, et al. Enhanced transduction of CAR-negative cells by protein IX-gene deleted adenovirus 5 vectors. Virology. 2011;410:192-200 pubmed publisher |
| Reinehr R, Sommerfeld A, Haussinger D. Insulin induces swelling-dependent activation of the epidermal growth factor receptor in rat liver. J Biol Chem. 2010;285:25904-12 pubmed publisher |
| Radhakrishnan S, Miranda E, Ekblad M, Holford A, Pizarro M, Lemoine N, et al. Efficacy of oncolytic mutants targeting pRb and p53 pathways is synergistically enhanced when combined with cytotoxic drugs in prostate cancer cells and tumor xenografts. Hum Gene Ther. 2010;21:1311-25 pubmed publisher |
| Okada T, Tsukano H, Endo M, Tabata M, Miyata K, Kadomatsu T, et al. Synoviocyte-derived angiopoietin-like protein 2 contributes to synovial chronic inflammation in rheumatoid arthritis. Am J Pathol. 2010;176:2309-19 pubmed publisher |
| Kessentini Zouari R, Jebali J, Taboubi S, Srairi Abid N, Morjen M, Kallech Ziri O, et al. CC-PLA2-1 and CC-PLA2-2, two Cerastes cerastes venom-derived phospholipases A2, inhibit angiogenesis both in vitro and in vivo. Lab Invest. 2010;90:510-9 pubmed publisher |
| Zahn G, Volk K, Lewis G, Vossmeyer D, Stragies R, Heier J, et al. Assessment of the integrin alpha5beta1 antagonist JSM6427 in proliferative vitreoretinopathy using in vitro assays and a rabbit model of retinal detachment. Invest Ophthalmol Vis Sci. 2010;51:1028-35 pubmed publisher |
| Rowland T, Miller L, Blaschke A, Doss E, Bonham A, Hikita S, et al. Roles of integrins in human induced pluripotent stem cell growth on Matrigel and vitronectin. Stem Cells Dev. 2010;19:1231-40 pubmed publisher |
| Shelton L, Rada J. Inhibition of human scleral fibroblast cell attachment to collagen type I by TGFBIp. Invest Ophthalmol Vis Sci. 2009;50:3542-52 pubmed publisher |
| Juric V, Chen C, Lau L. Fas-mediated apoptosis is regulated by the extracellular matrix protein CCN1 (CYR61) in vitro and in vivo. Mol Cell Biol. 2009;29:3266-79 pubmed publisher |
| Beauvais D, Ell B, McWhorter A, Rapraeger A. Syndecan-1 regulates alphavbeta3 and alphavbeta5 integrin activation during angiogenesis and is blocked by synstatin, a novel peptide inhibitor. J Exp Med. 2009;206:691-705 pubmed publisher |
| Heikkilä O, Susi P, Stanway G, Hyypia T. Integrin alphaVbeta6 is a high-affinity receptor for coxsackievirus A9. J Gen Virol. 2009;90:197-204 pubmed publisher |
| Schmid M, Varner J. Chapter 15. Methods to study myeloid cell roles in angiogenesis. Methods Enzymol. 2008;445:343-71 pubmed publisher |
| Ma C, Rong Y, Radiloff D, Datto M, Centeno B, Bao S, et al. Extracellular matrix protein betaig-h3/TGFBI promotes metastasis of colon cancer by enhancing cell extravasation. Genes Dev. 2008;22:308-21 pubmed publisher |
| Sonabend A, Ulasov I, Tyler M, Rivera A, Mathis J, Lesniak M. Mesenchymal stem cells effectively deliver an oncolytic adenovirus to intracranial glioma. Stem Cells. 2008;26:831-41 pubmed publisher |
| Fukushima Y, Tamura M, Nakagawa H, Itoh K. Induction of glioma cell migration by vitronectin in human serum and cerebrospinal fluid. J Neurosurg. 2007;107:578-85 pubmed |
| Hakkarainen T, Sarkioja M, Lehenkari P, Miettinen S, Ylikomi T, Suuronen R, et al. Human mesenchymal stem cells lack tumor tropism but enhance the antitumor activity of oncolytic adenoviruses in orthotopic lung and breast tumors. Hum Gene Ther. 2007;18:627-41 pubmed |
| Elayadi A, Samli K, Prudkin L, Liu Y, Bian A, Xie X, et al. A peptide selected by biopanning identifies the integrin alphavbeta6 as a prognostic biomarker for nonsmall cell lung cancer. Cancer Res. 2007;67:5889-95 pubmed |
| Zheng S, Ulasov I, Han Y, Tyler M, Zhu Z, Lesniak M. Fiber-knob modifications enhance adenoviral tropism and gene transfer in malignant glioma. J Gene Med. 2007;9:151-60 pubmed |
| Tyler M, Ulasov I, Borovjagin A, Sonabend A, Khramtsov A, Han Y, et al. Enhanced transduction of malignant glioma with a double targeted Ad5/3-RGD fiber-modified adenovirus. Mol Cancer Ther. 2006;5:2408-16 pubmed |
| Maginnis M, Forrest J, Kopecky Bromberg S, Dickeson S, Santoro S, Zutter M, et al. Beta1 integrin mediates internalization of mammalian reovirus. J Virol. 2006;80:2760-70 pubmed |
| Engesaeter B, Bonsted A, Berg K, Høgset A, Engebraten O, Fodstad Ø, et al. PCI-enhanced adenoviral transduction employs the known uptake mechanism of adenoviral particles. Cancer Gene Ther. 2005;12:439-48 pubmed |
| Wang T, Ward Y, Tian L, Lake R, Guedez L, Stetler Stevenson W, et al. CD97, an adhesion receptor on inflammatory cells, stimulates angiogenesis through binding integrin counterreceptors on endothelial cells. Blood. 2005;105:2836-44 pubmed |
