Integrin β3 Antibody, clone 25E11 | EMD Millipore MAB1957 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Integrin β3 Antibody, clone 25E11

catalog :

MAB1957

quantity :

100 µg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

25E11

reactivity :

human, mouse

application :

immunocytochemistry, immunoprecipitation, flow cytometry

citations: 17

Published Application/Species/Sample/Dilution	Reference
flow cytometry; mouse; loading ...; fig 7B	Farnoodian M, Kinter J, Yadranji Aghdam S, Zaitoun I, Sorenson C, Sheibani N. Expression of pigment epithelium-derived factor and thrombospondin-1 regulate proliferation and migration of retinal pigment epithelial cells. Physiol Rep. 2015;3: pubmed publisher
flow cytometry; mouse	Morrison M, Palenski T, Jamali N, Sheibani N, Sorenson C. Modulation of vascular cell function by bim expression. Int J Cell Biol. 2013;2013:297537 pubmed publisher
flow cytometry; mouse; 1:200	Zhao Y, Wang S, Sorenson C, Teixeira L, Dubielzig R, Peters D, et al. Cyp1b1 mediates periostin regulation of trabecular meshwork development by suppression of oxidative stress. Mol Cell Biol. 2013;33:4225-40 pubmed publisher
flow cytometry; mouse	Grutzmacher C, Park S, Zhao Y, Morrison M, Sheibani N, Sorenson C. Aberrant production of extracellular matrix proteins and dysfunction in kidney endothelial cells with a short duration of diabetes. Am J Physiol Renal Physiol. 2013;304:F19-30 pubmed publisher
	Zhang Z, Shively J. Acceleration of bone repair in NOD/SCID mice by human monoosteophils, novel LL-37-activated monocytes. PLoS ONE. 2013;8:e67649 pubmed publisher
	Burnett L, Rahmany M, Richter J, Aboushwareb T, Eberli D, Ward C, et al. Hemostatic properties and the role of cell receptor recognition in human hair keratin protein hydrogels. Biomaterials. 2013;34:2632-40 pubmed publisher
	Cox R, Livesay S, Johnson M, Ohi M, Williams J. The human metapneumovirus fusion protein mediates entry via an interaction with RGD-binding integrins. J Virol. 2012;86:12148-60 pubmed publisher
	Hasebe A, Nakamura Y, Tashima H, Takahashi K, Iijima M, Yoshimoto N, et al. The C-terminal region of NELL1 mediates osteoblastic cell adhesion through integrin ?3?1. FEBS Lett. 2012;586:2500-6 pubmed publisher
	Carrillo L, Arciniegas E, Rojas H, Ram rez R. Immunolocalization of endocan during the endothelial-mesenchymal transition process. Eur J Histochem. 2011;55:e13 pubmed
	Sheibani N, Morrison M, Gurel Z, Park S, Sorenson C. BIM deficiency differentially impacts the function of kidney endothelial and epithelial cells through modulation of their local microenvironment. Am J Physiol Renal Physiol. 2012;302:F809-19 pubmed publisher
	Zhang Y, Chen M, Venugopal S, Zhou Y, Xiang W, Li Y, et al. Isthmin exerts pro-survival and death-promoting effect on endothelial cells through alphavbeta5 integrin depending on its physical state. Cell Death Dis. 2011;2:e153 pubmed publisher
	Grutzmacher C, Park S, Elmergreen T, Tang Y, Scheef E, Sheibani N, et al. Opposing effects of bim and bcl-2 on lung endothelial cell migration. Am J Physiol Lung Cell Mol Physiol. 2010;299:L607-20 pubmed publisher
	Fujiwara T, Kawakatsu T, Tayama S, Kobayashi Y, Sugiura N, Kimata K, et al. Hyaluronan-CD44 pathway regulates orientation of mitotic spindle in normal epithelial cells. Genes Cells. 2008;13:759-70 pubmed publisher
	Kondo S, Scheef E, Sheibani N, Sorenson C. PECAM-1 isoform-specific regulation of kidney endothelial cell migration and capillary morphogenesis. Am J Physiol Cell Physiol. 2007;292:C2070-83 pubmed
	Driss A, Charrier L, Yan Y, Nduati V, Sitaraman S, Merlin D. Dystroglycan receptor is involved in integrin activation in intestinal epithelia. Am J Physiol Gastrointest Liver Physiol. 2006;290:G1228-42 pubmed
	Short S, Derrien A, Narsimhan R, Lawler J, Ingber D, Zetter B. Inhibition of endothelial cell migration by thrombospondin-1 type-1 repeats is mediated by beta1 integrins. J Cell Biol. 2005;168:643-53 pubmed
	Akimov S, Krylov D, Fleischman L, Belkin A. Tissue transglutaminase is an integrin-binding adhesion coreceptor for fibronectin. J Cell Biol. 2000;148:825-38 pubmed

product information

Catalog Number :

MAB1957

Subcategory :

Cell Structure

Product Name :

Anti-Integrin β3 Antibody, clone 25E11

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P05106

Host Name :

Mouse

Antigen :

Integrin β3

Clone :

25E11

Conjugate :

Purified

Isotype :

IgM

Product Description :

Anti-Integrin β3 Antibody, clone 25E11

Cross Reactivity :

Human

ALT Names :

CD61

Immunogen :

Normal blood mononuclear cells activated by mixed lymphocyte reaction and cultured for 10 days in medium containing IL-2.

Specificity :

Reacts with human integrin beta3 (GPIIIa, vitronectin receptor beta chain). The protein detectable is a complex of CD41 and CD61. The apparent molecular weight of the GPIIIa by SDS-PAGE is 105 kDa reduced and 90 kDa unreduced. Ligands are fibronectin, fibrinogen, von Willebrand factor, vitronectin and thrombospondin. Residues 237-248 of GPIIIa or CD61 are critical in adhesive protein binding. The monocytoid cell line U937 is highly positive. (original paper claimed IgG2ak)

Package Size :

100 µg

Uses :

Flow Cytometry;Immunoprecipitation;Immunocytochemistry;Affects Function

Storage :

Maintain between 2 and 8°C.