This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
EMD Millipore
other brands :
Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava
product type :
antibody
product name :
Laminin α5 Antibody, clone 4C7
catalog :
MAB1924
quantity :
100 μL
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
4C7

The same clone is also sold as:
reactivity :
human
application :
immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - frozen section
citations: 17
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - frozen section; human; 1:30,000; loading ...; fig 1
Preuße C, Allenbach Y, Hoffmann O, Goebel H, Pehl D, Radke J, et al. Differential roles of hypoxia and innate immunity in juvenile and adult dermatomyositis. Acta Neuropathol Commun. 2016;4:45 pubmed publisher
  • immunohistochemistry - frozen section; human; fig 4
Månsson Broberg A, Rodin S, Bulatovic I, Ibarra C, Löfling M, Genead R, et al. Wnt/?-Catenin Stimulation and Laminins Support Cardiovascular Cell Progenitor Expansion from Human Fetal Cardiac Mesenchymal Stromal Cells. Stem Cell Reports. 2016;6:607-617 pubmed publisher
  • immunocytochemistry; human; fig 1
Laperle A, Hsiao C, Lampe M, Mortier J, Saha K, Palecek S, et al. α-5 Laminin Synthesized by Human Pluripotent Stem Cells Promotes Self-Renewal. Stem Cell Reports. 2015;5:195-206 pubmed publisher
  • immunocytochemistry; human
Tang X, Richardson W, Fitch R, Brown C, Isaacs R, Chen J. A new non-enzymatic method for isolating human intervertebral disc cells preserves the phenotype of nucleus pulposus cells. Cytotechnology. 2014;66:979-86 pubmed publisher
Klotz B, Oosterhoff L, Utomo L, Lim K, Vallmajo Martin Q, Clevers H, et al. A Versatile Biosynthetic Hydrogel Platform for Engineering of Tissue Analogues. Adv Healthc Mater. 2019;8:e1900979 pubmed publisher
Jeon H, Kim J, Choi J, Han E, Song C, Lee J, et al. Effects of the Extracts from Fruit and Stem of Camellia japonica on Induced Pluripotency and Wound Healing. J Clin Med. 2018;7: pubmed publisher
Mazza G, Rombouts K, Rennie Hall A, Urbani L, Vinh Luong T, Al Akkad W, et al. Decellularized human liver as a natural 3D-scaffold for liver bioengineering and transplantation. Sci Rep. 2015;5:13079 pubmed publisher
Radovanovic D, Peikert K, Lindström M, Domellöf F. Sympathetic innervation of human muscle spindles. J Anat. 2015;226:542-8 pubmed publisher
Chon B, Lee E, Jing L, Setton L, Chen J. Human umbilical cord mesenchymal stromal cells exhibit immature nucleus pulposus cell phenotype in a laminin-rich pseudo-three-dimensional culture system. Stem Cell Res Ther. 2013;4:120 pubmed publisher
Mfopou J, Geeraerts M, Dejene R, Van Langenhoven S, Aberkane A, van Grunsven L, et al. Efficient definitive endoderm induction from mouse embryonic stem cell adherent cultures: a rapid screening model for differentiation studies. Stem Cell Res. 2014;12:166-77 pubmed publisher
Orlando G, Booth C, Wang Z, Totonelli G, Ross C, Moran E, et al. Discarded human kidneys as a source of ECM scaffold for kidney regeneration technologies. Biomaterials. 2013;34:5915-25 pubmed publisher
Sekine K, Takebe T, Suzuki Y, Kamiya A, Nakauchi H, Taniguchi H. Highly efficient generation of definitive endoderm lineage from human induced pluripotent stem cells. Transplant Proc. 2012;44:1127-9 pubmed publisher
Ohmine S, Squillace K, Hartjes K, Deeds M, Armstrong A, Thatava T, et al. Reprogrammed keratinocytes from elderly type 2 diabetes patients suppress senescence genes to acquire induced pluripotency. Aging (Albany NY). 2012;4:60-73 pubmed
Ohmine S, Dietz A, Deeds M, Hartjes K, Miller D, Thatava T, et al. Induced pluripotent stem cells from GMP-grade hematopoietic progenitor cells and mononuclear myeloid cells. Stem Cell Res Ther. 2011;2:46 pubmed publisher
Takata A, Otsuka M, Kogiso T, Kojima K, Yoshikawa T, Tateishi R, et al. Direct differentiation of hepatic cells from human induced pluripotent stem cells using a limited number of cytokines. Hepatol Int. 2011;5:890-8 pubmed publisher
Thatava T, Nelson T, Edukulla R, Sakuma T, Ohmine S, Tonne J, et al. Indolactam V/GLP-1-mediated differentiation of human iPS cells into glucose-responsive insulin-secreting progeny. Gene Ther. 2011;18:283-93 pubmed publisher
Klinge L, Harris J, Sewry C, Charlton R, Anderson L, Laval S, et al. Dysferlin associates with the developing T-tubule system in rodent and human skeletal muscle. Muscle Nerve. 2010;41:166-73 pubmed publisher
product information
Catalog Number :
MAB1924
Subcategory :
Cell Structure
Product Name :
Anti-Laminin α5 Antibody, clone 4C7
Product Type :
Antibodies
Clonality :
Monoclonal Antibody
Gene ID :
O15230
Host Name :
Mouse
Antigen :
Laminin α5
Clone :
4C7
Conjugate :
Ascites
Isotype :
IgG2a
Product Description :
Anti-Laminin α5 Antibody, clone 4C7
Cross Reactivity :
Human
Immunogen :
Purified human laminin
Specificity :
Reacts with the globular domain of the alpha5 chain of intact laminin and blocks the neurite stimulating activity of laminin. This antibody was originally thought to recognize laminin alpha 1 or A, but further characterization has confirmed its specificity for the laminin alpha 5 chain [see Tiger, C.F. (1997) J. Biol. Chem. 272: 28590].
Package Size :
100 μL
Uses :
ELISA;Immunohistochemistry;Immunoprecipitation
Storage :
Maintain for 1 year at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
company information
EMD Millipore
290 Concord Road
Billerica, Massachusetts 01821
bioscienceshelp@emdchemical.com
https://www.emdmillipore.com
888-854-3417
headquarters: United States
EMD Millipore is the Life Science division of Merck KGaA of Darmstadt, Germany

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