This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
EMD Millipore
other brands :
Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava
product type :
antibody
product name :
Fibrillin Antibody, clone 11C1.3
catalog :
MAB1919
quantity :
100 µL
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
11C1.3

The same clone is also sold as:
reactivity :
human, bovine
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section
citations: 13
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - paraffin section; human; 2.5 ug/ml; loading ...; fig 7b, g
Menz C, Parsi M, Adams J, Sideek M, Kopecki Z, Cowin A, et al. LTBP-2 Has a Single High-Affinity Binding Site for FGF-2 and Blocks FGF-2-Induced Cell Proliferation. PLoS ONE. 2015;10:e0135577 pubmed publisher
  • immunohistochemistry; human; 1:200
Wang F, Calderone K, Smith N, Do T, Helfrich Y, Johnson T, et al. Marked disruption and aberrant regulation of elastic fibres in early striae gravidarum. Br J Dermatol. 2015;173:1420-30 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:100; fig 2
Grewal N, Franken R, Mulder B, Goumans M, Lindeman J, Jongbloed M, et al. Histopathology of aortic complications in bicuspid aortic valve versus Marfan syndrome: relevance for therapy?. Heart Vessels. 2016;31:795-806 pubmed publisher
  • immunocytochemistry; human
Hu Q, Loeys B, Coucke P, De Paepe A, Mecham R, Choi J, et al. Fibulin-5 mutations: mechanisms of impaired elastic fiber formation in recessive cutis laxa. Hum Mol Genet. 2006;15:3379-86 pubmed
Filla M, Dimeo K, Tong T, Peters D. Disruption of fibronectin matrix affects type IV collagen, fibrillin and laminin deposition into extracellular matrix of human trabecular meshwork (HTM) cells. Exp Eye Res. 2017;165:7-19 pubmed publisher
Vranka J, Bradley J, Yang Y, Keller K, Acott T. Mapping molecular differences and extracellular matrix gene expression in segmental outflow pathways of the human ocular trabecular meshwork. PLoS ONE. 2015;10:e0122483 pubmed publisher
Beene L, Wang L, Hubmacher D, Keene D, Reinhardt D, Annis D, et al. Nonselective assembly of fibrillin 1 and fibrillin 2 in the rodent ocular zonule and in cultured cells: implications for Marfan syndrome. Invest Ophthalmol Vis Sci. 2013;54:8337-44 pubmed publisher
Tran C, Michelet J, Simonetti L, Fiat F, Garrigues A, Potter A, et al. In vitro and in vivo studies with tetra-hydro-jasmonic acid (LR2412) reveal its potential to correct signs of skin ageing. J Eur Acad Dermatol Venereol. 2014;28:415-23 pubmed publisher
Gabriel L, Wang L, Bader H, Ho J, Majors A, Hollyfield J, et al. ADAMTSL4, a secreted glycoprotein widely distributed in the eye, binds fibrillin-1 microfibrils and accelerates microfibril biogenesis. Invest Ophthalmol Vis Sci. 2012;53:461-9 pubmed publisher
Hatzirodos N, Bayne R, Irving Rodgers H, Hummitzsch K, Sabatier L, Lee S, et al. Linkage of regulators of TGF-? activity in the fetal ovary to polycystic ovary syndrome. FASEB J. 2011;25:2256-65 pubmed publisher
Kutz W, Wang L, Bader H, Majors A, Iwata K, Traboulsi E, et al. ADAMTS10 protein interacts with fibrillin-1 and promotes its deposition in extracellular matrix of cultured fibroblasts. J Biol Chem. 2011;286:17156-67 pubmed publisher
Prodoehl M, Irving Rodgers H, Bonner W, Sullivan T, Micke G, Gibson M, et al. Fibrillins and latent TGFbeta binding proteins in bovine ovaries of offspring following high or low protein diets during pregnancy of dams. Mol Cell Endocrinol. 2009;307:133-41 pubmed publisher
Rossi A, Pasqui D, Barbucci R, Gerli R, Weber E. The topography of microstructured surfaces differently affects fibrillin deposition by blood and lymphatic endothelial cells in culture. Tissue Eng Part A. 2009;15:525-33 pubmed publisher
product information
Catalog Number :
MAB1919
Subcategory :
Cell Structure
Product Name :
Anti-Fibrillin Antibody, clone 11C1.3
Product Type :
Antibodies
Clonality :
Monoclonal Antibody
Gene ID :
P35555
Host Name :
Mouse
Antigen :
Fibrillin
Clone :
11C1.3
Conjugate :
Purified
Isotype :
IgG1κ
Product Description :
Anti-Fibrillin Antibody, clone 11C1.3
Cross Reactivity :
Bovine;Human;Pig
Immunogen :
Bovine zonular fibrils
Specificity :
Bovine zonular fibrils. Reacts well with human elastin microfibrils and can be used to investigate the presence and organization of these fibrils either in Marfan patients or in fibroblasts obtained from these patients.
Package Size :
100 µL
Uses :
ELISA;Immunofluorescence;Immunoprecipitation;Western Blotting;Immunohistochemistry (Paraffin)
Storage :
Maintain at -20°C in undiluted aliquots for up to 12 months. Avoid repeated freeze/thaw cycles.
company information
EMD Millipore
290 Concord Road
Billerica, Massachusetts 01821
bioscienceshelp@emdchemical.com
https://www.emdmillipore.com
888-854-3417
headquarters: United States
EMD Millipore is the Life Science division of Merck KGaA of Darmstadt, Germany

Hundreds of New Antibodies in the areas of:
  • • Cancer
  • • Nuclear Signaling
  • • Apoptosis
  • • Cardiovascular Disease
  • • Developmental Biology
  • • Metabolic Disease
  • • Neurodegenerative Disease
  • • Cell Biology
View all the new antibodies at www.emdmillipore.com.