Migration Inhibitory Factor Related Proteins 8 and 14 Antibody, clone AHN-17 | EMD Millipore MAB1789 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Migration Inhibitory Factor Related Proteins 8 and 14 Antibody, clone AHN-17

catalog :

MAB1789

quantity :

100 µg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

AHN-17

reactivity :

human

application :

western blot, immunocytochemistry

citations: 2

Reference
Caruso N, Herberth B, Bartoli M, Puppo F, Dumonceaux J, Zimmermann A, et al. Deregulation of the protocadherin gene FAT1 alters muscle shapes: implications for the pathogenesis of facioscapulohumeral dystrophy. PLoS Genet. 2013;9:e1003550 pubmed publisher
Koh S, Wei J, Li X, Huang R, Doan N, Scolyer R, et al. Differential gene expression profiling of primary cutaneous melanoma and sentinel lymph node metastases. Mod Pathol. 2012;25:828-37 pubmed publisher

product information

Catalog Number :

MAB1789

Subcategory :

Inflammation & Immunology

Product Name :

Anti-Migration Inhibitory Factor Related Proteins 8 and 14 Antibody, clone AHN-17

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P05109

Host Name :

Mouse

Antigen :

Migration Inhibitory Factor Related Proteins 8 and 14

Clone :

AHN-17

Conjugate :

Purified

Isotype :

IgG1

Product Description :

Anti-Migration Inhibitory Factor Related Proteins 8 and 14 Antibody, clone AHN-17

Cross Reactivity :

Human

Background :

Migration inhibitory factor-related proteins (MRP) -8 and -14 belong to the S-100 family of calcium binding proteins associated with myeloid cell differentiation. They are highly expressed in resting neutrophils, keratinocytes (particularly in psoriasis), in infiltrating tissue macrophages and on epithelial cells in active inflammatory disease. The heterogeneity of macrophage subpopulations in chronic or acute inflammation is reflected by different expression of MRP8 and MRP14. Phagocytes expressing MRP8 and MRP14 belong to the early infiltrating cells, while MRP8 alone is found in chronic inflammatory tissues. The partially antagonistic functions of MRP8, MRP14 and of the Ca2+-dependent MRP8/14 heterocomplex makes them versatile mediators.

ALT Names :

MRP-8 Myeloid-Related Protein-8 Calgranulin A S100 Calcium-binding Protein A8 Leukocyte L1 cplx Light & Heavy Chain; Calprotectin

Immunogen :

Neutrophils

Specificity :

Migration Inhibitory Factor Releasing Proteins -8 and -14

Package Size :

100 µg

Uses :

Western Blotting;Immunocytochemistry

Storage :

Maintain at 2-8°C in undiluted aliquots for up to 6 months from date of receipt.