Integrin α4 Antibody, clone P1H4 | EMD Millipore MAB16983 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Integrin α4 Antibody, clone P1H4

catalog :

MAB16983

quantity :

100 µg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

P1H4

reactivity :

human

application :

immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, blocking or activating experiments

citations: 17

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human; 1:100; fig s5	De Franceschi N, Arjonen A, Elkhatib N, Denessiouk K, Wrobel A, Wilson T, et al. Selective integrin endocytosis is driven by interactions between the integrin Î±-chain and AP2. Nat Struct Mol Biol. 2016;23:172-9 pubmed publisher
flow cytometry; human	Hui T, SÃ¸rensen E, Rittling S. Osteopontin binding to the alpha 4 integrin requires highest affinity integrin conformation, but is independent of post-translational modifications of osteopontin. Matrix Biol. 2015;41:19-25 pubmed publisher
blocking or activating experiments; human; 10 ug/ml flow cytometry; human; 2 ug/25 x104cells	Stampolidis P, Ullrich A, Iacobelli S. LGALS3BP, lectin galactoside-binding soluble 3 binding protein, promotes oncogenic cellular events impeded by antibody intervention. Oncogene. 2015;34:39-52 pubmed publisher
	Young S, McCabe K, Bartakova A, Delaney J, Pizzo D, Newbury R, et al. Integrin Î±4 Enhances Metastasis and May Be Associated with Poor Prognosis in MYCN-low Neuroblastoma. PLoS ONE. 2015;10:e0120815 pubmed publisher
	Tanaka R, Seki Y, Saito Y, Kamiya S, Fujita M, Okutsu H, et al. Tenascin-C-derived peptide TNIIIA2 highly enhances cell survival and platelet-derived growth factor (PDGF)-dependent cell proliferation through potentiated and sustained activation of integrin ?5?1. J Biol Chem. 2014;289:17699-708 pubmed publisher
	Tjomsland V, EllegÃ¥rd R, KjÃ¶lhede P, Wodlin N, Hinkula J, Lifson J, et al. Blocking of integrins inhibits HIV-1 infection of human cervical mucosa immune cells with free and complement-opsonized virions. Eur J Immunol. 2013;43:2361-72 pubmed publisher
	Matsunaga T, Fukai F, Kameda T, Shide K, Shimoda H, Torii E, et al. Potentiated activation of VLA-4 and VLA-5 accelerates proplatelet-like formation. Ann Hematol. 2012;91:1633-43 pubmed publisher
	Li Q, Ding X, Thomas J, Harding C, Pecora N, Ziady A, et al. Rv2468c, a novel Mycobacterium tuberculosis protein that costimulates human CD4+ T cells through VLA-5. J Leukoc Biol. 2012;91:311-20 pubmed publisher
	Khaled S, Gupta K, Kucik D. Ionizing radiation increases adhesiveness of human aortic endothelial cells via a chemokine-dependent mechanism. Radiat Res. 2012;177:594-601 pubmed
	Abdi J, Engels F, Garssen J, Redegeld F. Toll-like receptor-9 triggering modulates expression of ?-4 integrin on human B lymphocytes and their adhesion to extracellular matrix proteins. Exp Hematol. 2011;39:927-33 pubmed publisher
	Teo J, Ng R, Ng C, Lin A. Surface characteristics of acrylic modified polysulfone membranes improves renal proximal tubule cell adhesion and spreading. Acta Biomater. 2011;7:2060-9 pubmed publisher
	Malara A, Gruppi C, Rebuzzini P, Visai L, Perotti C, Moratti R, et al. Megakaryocyte-matrix interaction within bone marrow: new roles for fibronectin and factor XIII-A. Blood. 2011;117:2476-83 pubmed publisher
	Faralli J, Newman J, Sheibani N, Dedhar S, Peters D. Integrin-linked kinase regulates integrin signaling in human trabecular meshwork cells. Invest Ophthalmol Vis Sci. 2011;52:1684-92 pubmed publisher
	Nevo J, Mai A, Tuomi S, Pellinen T, Pentikäinen O, Heikkila P, et al. Mammary-derived growth inhibitor (MDGI) interacts with integrin ?-subunits and suppresses integrin activity and invasion. Oncogene. 2010;29:6452-63 pubmed publisher
	Hibbert B, Ma X, Pourdjabbar A, Holm E, Rayner K, Chen Y, et al. Inhibition of endothelial progenitor cell glycogen synthase kinase-3beta results in attenuated neointima formation and enhanced re-endothelialization after arterial injury. Cardiovasc Res. 2009;83:16-23 pubmed publisher
	Mische S, He Y, Ma L, Li M, Serr M, Hays T. Dynein light intermediate chain: an essential subunit that contributes to spindle checkpoint inactivation. Mol Biol Cell. 2008;19:4918-29 pubmed publisher
	Przybyło M, Pochec E, Link Lenczowski P, Litynska A. Beta1-6 branching of cell surface glycoproteins may contribute to uveal melanoma progression by up-regulating cell motility. Mol Vis. 2008;14:625-36 pubmed

product information

Catalog Number :

MAB16983

Subcategory :

Cell Structure

Product Name :

Anti-Integrin α4 Antibody, clone P1H4

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P13612

Host Name :

Mouse

Antigen :

Integrin α4

Clone :

P1H4

Conjugate :

Purified

Isotype :

IgG1

Product Description :

Anti-Integrin α4 Antibody, clone P1H4

Cross Reactivity :

Human;Primate

ALT Names :

CD49d

Specificity :

The involvement of integrins in vascular proliferation, adhesion, and wound repair and have been well-documented. The integrin family of cell adhesion receptors consists of at least 16 membrane-associated heterodimers, composed of an alpha and beta subunit that associate in a non-covalent manner. The structure and functional diversity of the integrin family are based upon the pairing abilities of the individual alpha and beta subunits. Monoclonal antibody MAB16983 was produced by immunization with human T lymphocytes. The antibody is reactive with integrin a4 from primate and human species.

Package Size :

100 µg

Uses :

ELISA;Flow Cytometry;Immunoprecipitation;Immunocytochemistry;Immunohistochemistry;Affects Function

Storage :

Maintain at +2-8C.