This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
EMD Millipore
other brands :
Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava
product type :
antibody
product name :
Troponin I Antibody, a.a. 87-93, clone C5
catalog :
MAB1691
quantity :
100 µg
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
C5

The same clone is also sold as:
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section
citations: 26
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human; fig 1
Jha R, Xu R, Xu C. Efficient differentiation of cardiomyocytes from human pluripotent stem cells with growth factors. Methods Mol Biol. 2015;1299:115-31 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:500
Itier J, Ret G, Viale S, Sweet L, Bangari D, Caron A, et al. Effective clearance of GL-3 in a human iPSC-derived cardiomyocyte model of Fabry disease. J Inherit Metab Dis. 2014;37:1013-22 pubmed publisher
  • western blot; mouse; 1:500
Yuan B, Wan P, Chu D, Nie J, Cao Y, Luo W, et al. A cardiomyocyte-specific Wdr1 knockout demonstrates essential functional roles for actin disassembly during myocardial growth and maintenance in mice. Am J Pathol. 2014;184:1967-80 pubmed publisher
  • immunocytochemistry; human; 1:400
Clements M, Thomas N. High-throughput multi-parameter profiling of electrophysiological drug effects in human embryonic stem cell derived cardiomyocytes using multi-electrode arrays. Toxicol Sci. 2014;140:445-61 pubmed publisher
  • immunohistochemistry - paraffin section; mouse
Wijnen W, van der Made I, van den Oever S, Hiller M, de Boer B, Picavet D, et al. Cardiomyocyte-specific miRNA-30c over-expression causes dilated cardiomyopathy. PLoS ONE. 2014;9:e96290 pubmed publisher
  • immunocytochemistry; human
Fuentes T, Appleby N, Tsay E, Martinez J, Bailey L, Hasaniya N, et al. Human neonatal cardiovascular progenitors: unlocking the secret to regenerative ability. PLoS ONE. 2013;8:e77464 pubmed publisher
  • immunocytochemistry; human; 1:500
Myers F, Silver J, Zhuge Y, Beygui R, Zarins C, Lee L, et al. Robust pluripotent stem cell expansion and cardiomyocyte differentiation via geometric patterning. Integr Biol (Camb). 2013;5:1495-506 pubmed publisher
  • western blot; mouse
Chang A, Huang J, Battiprolu P, Hill J, Kamm K, Stull J. The effects of neuregulin on cardiac Myosin light chain kinase gene-ablated hearts. PLoS ONE. 2013;8:e66720 pubmed publisher
  • immunohistochemistry; mouse
  • immunohistochemistry; rat
Sanbe A, Marunouchi T, Abe T, Tezuka Y, Okada M, Aoki S, et al. Phenotype of cardiomyopathy in cardiac-specific heat shock protein B8 K141N transgenic mouse. J Biol Chem. 2013;288:8910-21 pubmed publisher
  • immunocytochemistry; rat; 1:500
  • western blot; rat; 1:4000
Lang S, Robinson D, Wu H, Herron T, Wahr P, Westfall M. Myofilament incorporation and contractile function after gene transfer of cardiac troponin I Ser43/45Ala. Arch Biochem Biophys. 2013;535:49-55 pubmed publisher
  • immunocytochemistry; mouse; 1:300
  • immunocytochemistry; rat
Chun J, O Brien R, Song M, Wondrasch B, Berry S. Injection of vessel-derived stem cells prevents dilated cardiomyopathy and promotes angiogenesis and endogenous cardiac stem cell proliferation in mdx/utrn-/- but not aged mdx mouse models for duchenne muscular dystrophy. Stem Cells Transl Med. 2013;2:68-80 pubmed publisher
Goldfracht I, Efraim Y, Shinnawi R, Kovalev E, Huber I, Gepstein A, et al. Engineered heart tissue models from hiPSC-derived cardiomyocytes and cardiac ECM for disease modeling and drug testing applications. Acta Biomater. 2019;92:145-159 pubmed publisher
McLendon P, Davis G, Gulick J, Singh S, Xu N, Salomonis N, et al. An Unbiased High-Throughput Screen to Identify Novel Effectors That Impact on Cardiomyocyte Aggregate Levels. Circ Res. 2017;121:604-616 pubmed publisher
Lang S, Stevenson T, Schatz T, Biesiadecki B, Westfall M. Functional communication between PKC-targeted cardiac troponin I phosphorylation sites. Arch Biochem Biophys. 2017;627:1-9 pubmed publisher
Yamada T, Abe M, Lee J, Tatebayashi D, Himori K, Kanzaki K, et al. Muscle dysfunction associated with adjuvant-induced arthritis is prevented by antioxidant treatment. Skelet Muscle. 2015;5:20 pubmed publisher
Fuoco C, Rizzi R, Biondo A, Longa E, Mascaro A, Shapira Schweitzer K, et al. In vivo generation of a mature and functional artificial skeletal muscle. EMBO Mol Med. 2015;7:411-22 pubmed publisher
Kong Y, Carrion B, Singh R, Putnam A. Matrix identity and tractional forces influence indirect cardiac reprogramming. Sci Rep. 2013;3:3474 pubmed publisher
Palpant N, Houang E, Sham Y, Metzger J. pH-responsive titratable inotropic performance of histidine-modified cardiac troponin I. Biophys J. 2012;102:1570-9 pubmed publisher
Sanbe A, Marunouchi T, Yamauchi J, Tanonaka K, Nishigori H, Tanoue A. Cardioprotective effect of nicorandil, a mitochondrial ATP-sensitive potassium channel opener, prolongs survival in HSPB5 R120G transgenic mice. PLoS ONE. 2011;6:e18922 pubmed publisher
Liou Y, Hsieh S, Wu T, Chen J. Green tea extract given before regional myocardial ischemia-reperfusion in rats improves myocardial contractility by attenuating calcium overload. Pflugers Arch. 2010;460:1003-14 pubmed publisher
Emre N, Vidal J, Elia J, O Connor E, Paramban R, Hefferan M, et al. The ROCK inhibitor Y-27632 improves recovery of human embryonic stem cells after fluorescence-activated cell sorting with multiple cell surface markers. PLoS ONE. 2010;5:e12148 pubmed publisher
Sanbe A, Daicho T, Mizutani R, Endo T, Miyauchi N, Yamauchi J, et al. Protective effect of geranylgeranylacetone via enhancement of HSPB8 induction in desmin-related cardiomyopathy. PLoS ONE. 2009;4:e5351 pubmed publisher
Sanbe A, Yamauchi J, Miyamoto Y, Fujiwara Y, Murabe M, Tanoue A. Interruption of CryAB-amyloid oligomer formation by HSP22. J Biol Chem. 2007;282:555-63 pubmed
Uchida S, Fuke S, Tsukahara T. Upregulations of Gata4 and oxytocin receptor are important in cardiomyocyte differentiation processes of P19CL6 cells. J Cell Biochem. 2007;100:629-41 pubmed
Maloyan A, Sanbe A, Osinska H, Westfall M, Robinson D, Imahashi K, et al. Mitochondrial dysfunction and apoptosis underlie the pathogenic process in alpha-B-crystallin desmin-related cardiomyopathy. Circulation. 2005;112:3451-61 pubmed
Sanbe A, Osinska H, Villa C, Gulick J, Klevitsky R, Glabe C, et al. Reversal of amyloid-induced heart disease in desmin-related cardiomyopathy. Proc Natl Acad Sci U S A. 2005;102:13592-7 pubmed
product information
Catalog Number :
MAB1691
Subcategory :
Metabolism
Product Name :
Anti-Troponin I Antibody, a.a. 87-93, clone C5
Product Type :
Antibodies
Clonality :
Monoclonal Antibody
Gene ID :
P19429
Host Name :
Mouse
Antigen :
Troponin I
Clone :
C5
Conjugate :
Purified
Isotype :
IgG2b
Product Description :
Anti-Troponin I Antibody, a.a. 87-93, clone C5
Cross Reactivity :
Bovine;Chicken;Human;Mouse;Rabbit;Fish;Frog
Immunogen :
Bovine cardiac Troponin I.
Specificity :
Troponin I. Reacts with Troponin I from heart and skeletal muscle.
Package Size :
100 µg
Uses :
ELISA;Western Blotting
Storage :
Maintain refrigerated at +2-8°C for up to 6 months.
company information
EMD Millipore
290 Concord Road
Billerica, Massachusetts 01821
bioscienceshelp@emdchemical.com
https://www.emdmillipore.com
888-854-3417
headquarters: United States
EMD Millipore is the Life Science division of Merck KGaA of Darmstadt, Germany

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