This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
EMD Millipore
other brands :
Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava
product type :
antibody
product name :
Actinin α Antibody, clone AT6/172
catalog :
MAB1682
quantity :
100 µL
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
AT6/172
reactivity :
human, mouse, rat
application :
western blot, immunocytochemistry, immunoprecipitation
citations: 23
Published Application/Species/Sample/DilutionReference
  • immunocytochemistry; human; 1:100; loading ...; fig 5d, 7b
Latham S, Ehmke N, Reinke P, Taft M, Eicke D, Reindl T, et al. Variants in exons 5 and 6 of ACTB cause syndromic thrombocytopenia. Nat Commun. 2018;9:4250 pubmed publisher
  • immunocytochemistry; human
Murphy K, Morgan J, Wood J, Sadeli A, Murphy C, Russell P. The formation of cortical actin arrays in human trabecular meshwork cells in response to cytoskeletal disruption. Exp Cell Res. 2014;328:164-171 pubmed publisher
  • immunocytochemistry; mouse; 1:100
  • immunocytochemistry; rat
Chun J, O Brien R, Song M, Wondrasch B, Berry S. Injection of vessel-derived stem cells prevents dilated cardiomyopathy and promotes angiogenesis and endogenous cardiac stem cell proliferation in mdx/utrn-/- but not aged mdx mouse models for duchenne muscular dystrophy. Stem Cells Transl Med. 2013;2:68-80 pubmed publisher
Fernandes R, Hall A, Ferguson M, Lorenzen Schmidt I, Balasubramaniam V, Pyle W. Cardiac changes during the peri-menopausal period in a VCD-induced murine model of ovarian failure. Acta Physiol (Oxf). 2019;227:e13290 pubmed publisher
Jahan F, Madhavan S, Rolova T, Viazmina L, Grönholm M, Gahmberg C. Phosphorylation of the α-chain in the integrin LFA-1 enables β2-chain phosphorylation and α-actinin binding required for cell adhesion. J Biol Chem. 2018;293:12318-12330 pubmed publisher
Ning L, Paetau S, Nyman Huttunen H, Tian L, Gahmberg C. ICAM-5 affects spine maturation by regulation of NMDA receptor binding to α-actinin. Biol Open. 2015;4:125-36 pubmed publisher
Sun Y, Zhang H, Hu R, Sun J, Mao X, Zhao Z, et al. The expression and significance of neuronal iconic proteins in podocytes. PLoS ONE. 2014;9:e93999 pubmed publisher
Wickham A, Islam M, Mondal D, Phopase J, Sadhu V, Tamás E, et al. Polycaprolactone-thiophene-conjugated carbon nanotube meshes as scaffolds for cardiac progenitor cells. J Biomed Mater Res B Appl Biomater. 2014;102:1553-61 pubmed publisher
Gangoso E, Thirant C, Chneiweiss H, Medina J, Tabernero A. A cell-penetrating peptide based on the interaction between c-Src and connexin43 reverses glioma stem cell phenotype. Cell Death Dis. 2014;5:e1023 pubmed publisher
Vaquero J, Monte M, Dominguez M, Muntane J, Marin J. Differential activation of the human farnesoid X receptor depends on the pattern of expressed isoforms and the bile acid pool composition. Biochem Pharmacol. 2013;86:926-39 pubmed publisher
Feduska J, Garcia P, Brennan S, Bu S, Council L, Yoon K. N-glycosylation of ICAM-2 is required for ICAM-2-mediated complete suppression of metastatic potential of SK-N-AS neuroblastoma cells. BMC Cancer. 2013;13:261 pubmed publisher
Nguyen P, Hsiao S, Sivakumaran P, Lim S, Dilley R. Enrichment of neonatal rat cardiomyocytes in primary culture facilitates long-term maintenance of contractility in vitro. Am J Physiol Cell Physiol. 2012;303:C1220-8 pubmed publisher
Bertossi A, Aichinger M, Sansonetti P, Lech M, Neff F, Pal M, et al. Loss of Roquin induces early death and immune deregulation but not autoimmunity. J Exp Med. 2011;208:1749-56 pubmed publisher
Boëda B, Knowles P, Briggs D, Murray Rust J, Soriano E, Garvalov B, et al. Molecular recognition of the Tes LIM2-3 domains by the actin-related protein Arp7A. J Biol Chem. 2011;286:11543-54 pubmed publisher
Spassov A, Gredes T, Gedrange T, Lucke S, Morgenstern S, Pavlovic D, et al. Differential expression of myosin heavy chain isoforms in the masticatory muscles of dystrophin-deficient mice. Eur J Orthod. 2011;33:613-9 pubmed publisher
Pritschow B, Lange T, Kasch J, Kunert Keil C, Liedtke W, Brinkmeier H. Functional TRPV4 channels are expressed in mouse skeletal muscle and can modulate resting Ca2+ influx and muscle fatigue. Pflugers Arch. 2011;461:115-22 pubmed publisher
Temiz P, Weihl C, Pestronk A. Inflammatory myopathies with mitochondrial pathology and protein aggregates. J Neurol Sci. 2009;278:25-9 pubmed publisher
Yoon K, Phelps D, Bush R, Remack J, Billups C, Khoury J. ICAM-2 expression mediates a membrane-actin link, confers a nonmetastatic phenotype and reflects favorable tumor stage or histology in neuroblastoma. PLoS ONE. 2008;3:e3629 pubmed publisher
Takala H, Nurminen E, Nurmi S, Aatonen M, Strandin T, Takatalo M, et al. Beta2 integrin phosphorylation on Thr758 acts as a molecular switch to regulate 14-3-3 and filamin binding. Blood. 2008;112:1853-62 pubmed publisher
Park J, Will C, Martin B, Gullotti L, Friedrichs N, Buettner R, et al. Deficiency in the LIM-only protein FHL2 impairs assembly of extracellular matrix proteins. FASEB J. 2008;22:2508-20 pubmed publisher
Nyman Huttunen H, Tian L, Ning L, Gahmberg C. alpha-Actinin-dependent cytoskeletal anchorage is important for ICAM-5-mediated neuritic outgrowth. J Cell Sci. 2006;119:3057-66 pubmed
Xing Y, Ding J, Fan Q, Guan N. Diversities of podocyte molecular changes induced by different antiproteinuria drugs. Exp Biol Med (Maywood). 2006;231:585-93 pubmed
Nahirney P, Fischman D, Wang K. Myosin flares and actin leptomeres as myofibril assembly/disassembly intermediates in sonic muscle fibers. Cell Tissue Res. 2006;324:127-38 pubmed
product information
Catalog Number :
MAB1682
Subcategory :
Cell Structure
Product Name :
Anti-Actinin α Antibody, clone AT6/172
Product Type :
Antibodies
Clonality :
Monoclonal Antibody
Gene ID :
P12814
Host Name :
Mouse
Antigen :
Actinin α
Clone :
AT6/172
Conjugate :
Ascites
Isotype :
IgG1
Product Description :
Anti-Actinin α Antibody, clone AT6/172
Cross Reactivity :
Human
Immunogen :
Human platelet protein
Specificity :
Human alpha actinin. This antibody recognizes an epitope in the N-terminal region of alpha-actinin, probably between residues 1-24.
Package Size :
100 µL
Uses :
Immunofluorescence;Immunoprecipitation;Western Blotting
Storage :
Maintain frozen at -20°C for up to 12 months in undiluted aliquots. Avoid repeated freeze/thaw cycles.
company information
EMD Millipore
290 Concord Road
Billerica, Massachusetts 01821
bioscienceshelp@emdchemical.com
https://www.emdmillipore.com
888-854-3417
headquarters: United States
EMD Millipore is the Life Science division of Merck KGaA of Darmstadt, Germany

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