product summary
company name :
EMD Millipore
other brands :
Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava
product type :
antibody
product name :
Tubulin Antibody, beta III isoform, CT, clone TU-20 (Similar to TUJ1)
catalog :
MAB1637
quantity :
100 µL
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
TU-20

The same clone is also sold as:
reactivity :
Chinese softshell turtle, African green monkey, Paroedura, human, mouse, rat, dogs, chicken, bovine, pigs , domestic sheep, rhesus macaque
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section, In-Cell Western
more info or order :
citations: 230
Published Application/Species/Sample/DilutionReference
  • immunocytochemistry; mouse; 1:400; loading ...; fig 3f
Chan K, Nestor J, Huerta T, Certain N, Moody G, Kowal C, et al. Lupus autoantibodies act as positive allosteric modulators at GluN2A-containing NMDA receptors and impair spatial memory. Nat Commun. 2020;11:1403 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 1s1d
Onn L, Portillo M, Ilic S, Cleitman G, Stein D, Kaluski S, et al. SIRT6 is a DNA double-strand break sensor. elife. 2020;9: pubmed publisher
  • western blot; rat; 1:5000; loading ...; fig 1a
Zhou L, Shao C, Xie Y, Wang N, Xu S, Luo B, et al. Gab1 mediates PDGF signaling and is essential to oligodendrocyte differentiation and CNS myelination. elife. 2020;9: pubmed publisher
  • immunohistochemistry - paraffin section; rat; 1:400; loading ...; fig 6d
Mammone T, Chidlow G, Casson R, Wood J. Improved immunohistochemical detection of phosphorylated mitogen-activated protein kinases in the injured rat optic nerve head. Histochem Cell Biol. 2019;151:435-456 pubmed publisher
  • western blot; mouse; loading ...; fig 1e
Schaffer T, Smith J, Cook E, Phan T, Margolis S. PKCε Inhibits Neuronal Dendritic Spine Development through Dual Phosphorylation of Ephexin5. Cell Rep. 2018;25:2470-2483.e8 pubmed publisher
  • immunocytochemistry; human; loading ...; fig s1k
Wang C, Najm R, Xu Q, Jeong D, Walker D, Balestra M, et al. Gain of toxic apolipoprotein E4 effects in human iPSC-derived neurons is ameliorated by a small-molecule structure corrector. Nat Med. 2018;24:647-657 pubmed publisher
  • western blot; rat; 1:1000; loading ...; fig 3a
Arcego D, Toniazzo A, Krolow R, Lampert C, Berlitz C, Dos Santos Garcia E, et al. Impact of High-Fat Diet and Early Stress on Depressive-Like Behavior and Hippocampal Plasticity in Adult Male Rats. Mol Neurobiol. 2018;55:2740-2753 pubmed publisher
  • immunocytochemistry; mouse; 1:200; fig 2a
Jin X, Yu Z, Chen F, Lu G, Ding X, Xie L, et al. Neuronal Nitric Oxide Synthase in Neural Stem Cells Induces Neuronal Fate Commitment via the Inhibition of Histone Deacetylase 2. Front Cell Neurosci. 2017;11:66 pubmed publisher
  • western blot; mouse; loading ...; fig 2d
Po A, Begalli F, Abballe L, Alfano V, Besharat Z, Catanzaro G, et al. ?-Arrestin1/miR-326 Transcription Unit Is Epigenetically Regulated in Neural Stem Cells Where It Controls Stemness and Growth Arrest. Stem Cells Int. 2017;2017:5274171 pubmed publisher
  • immunohistochemistry - frozen section; rat; fig s1d
Wang D, Wang A, Wu F, Qiu X, Li Y, Chu J, et al. Sox10+ adult stem cells contribute to biomaterial encapsulation and microvascularization. Sci Rep. 2017;7:40295 pubmed publisher
  • immunohistochemistry - frozen section; chicken; 1:250; fig 8a
Kukreja S, Gautam P, Saxena R, Saxena M, Udaykumar N, Kumar A, et al. Identification of novel candidate regulators of retinotectal map formation through transcriptional profiling of the chick optic tectum. J Comp Neurol. 2017;525:459-477 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:500; fig 1
Vasconcelos F, Sessa A, Laranjeira C, Raposo A, Teixeira V, Hagey D, et al. MyT1 Counteracts the Neural Progenitor Program to Promote Vertebrate Neurogenesis. Cell Rep. 2016;17:469-483 pubmed publisher
  • immunohistochemistry - frozen section; mouse; fig 5
Fogarty L, Song B, Suppiah Y, Hasan S, Martin H, Hogan S, et al. Bcl-xL dependency coincides with the onset of neurogenesis in the developing mammalian spinal cord. Mol Cell Neurosci. 2016;77:34-46 pubmed publisher
  • immunocytochemistry; human; 1:400; fig s2
Ahmadian Baghbaderani B, Tian X, Scotty Cadet J, Shah K, Walde A, Tran H, et al. A Newly Defined and Xeno-Free Culture Medium Supports Every-Other-Day Medium Replacement in the Generation and Long-Term Cultivation of Human Pluripotent Stem Cells. PLoS ONE. 2016;11:e0161229 pubmed publisher
  • immunocytochemistry; human; 1:400; loading ...; tbl s4
  • western blot; human; 1:400; loading ...; tbl s4
Hansen S, Stummann T, Borland H, Hasholt L, Tumer Z, Nielsen J, et al. Induced pluripotent stem cell - derived neurons for the study of spinocerebellar ataxia type 3. Stem Cell Res. 2016;17:306-317 pubmed publisher
  • immunocytochemistry; human; 1:700; loading ...; fig 5a
Jaako K, Waniek A, Parik K, Klimaviciusa L, Aonurm Helm A, Noortoots A, et al. Prolyl endopeptidase is involved in the degradation of neural cell adhesion molecules in vitro. J Cell Sci. 2016;129:3792-3802 pubmed
  • immunocytochemistry; human; fig 1
Gill K, Hung S, Sharov A, Lo C, Needham K, Lidgerwood G, et al. Enriched retinal ganglion cells derived from human embryonic stem cells. Sci Rep. 2016;6:30552 pubmed publisher
  • immunocytochemistry; human; 1:50; fig 4
Cheng Y, Huang C, Lee Y, Tien L, Ku W, Chien R, et al. Knocking down of heat-shock protein 27 directs differentiation of functional glutamatergic neurons from placenta-derived multipotent cells. Sci Rep. 2016;6:30314 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; loading ...; fig s1a
Sanges D, Simonte G, Di Vicino U, Romo N, Pinilla I, Nicolas M, et al. Reprogramming Müller glia via in vivo cell fusion regenerates murine photoreceptors. J Clin Invest. 2016;126:3104-16 pubmed publisher
  • immunocytochemistry; human; 1:400; fig 1
Baghbaderani B, Syama A, Sivapatham R, Pei Y, Mukherjee O, Fellner T, et al. Detailed Characterization of Human Induced Pluripotent Stem Cells Manufactured for Therapeutic Applications. Stem Cell Rev. 2016;12:394-420 pubmed publisher
  • immunocytochemistry; mouse; 1:1000; loading ...; fig 3d
Jang H, Hong Y, Choi H, Song H, Byun S, Uhm S, et al. Changes in Parthenogenetic Imprinting Patterns during Reprogramming by Cell Fusion. PLoS ONE. 2016;11:e0156491 pubmed publisher
  • immunohistochemistry - frozen section; human; 1:100; fig 4
Deborde S, Omelchenko T, Lyubchik A, Zhou Y, He S, McNamara W, et al. Schwann cells induce cancer cell dispersion and invasion. J Clin Invest. 2016;126:1538-54 pubmed publisher
  • immunocytochemistry; human; 1:2000; fig 2
Francis K, Ton A, Xin Y, O Halloran P, Wassif C, Malik N, et al. Modeling Smith-Lemli-Opitz syndrome with induced pluripotent stem cells reveals a causal role for Wnt/β-catenin defects in neuronal cholesterol synthesis phenotypes. Nat Med. 2016;22:388-96 pubmed publisher
  • immunohistochemistry; mouse; fig 5
Zhang W, Kim P, Chen Z, Lokman H, Qiu L, Zhang K, et al. MiRNA-128 regulates the proliferation and neurogenesis of neural precursors by targeting PCM1 in the developing cortex. elife. 2016;5: pubmed publisher
  • immunocytochemistry; mouse; 1:500; fig 5d
Chen Y, Peng C, Tung Y. Flip channel: A microfluidic device for uniform-sized embryoid body formation and differentiation. Biomicrofluidics. 2015;9:054111 pubmed publisher
  • immunohistochemistry; human
Adesina A, Veo B, Courteau G, Mehta V, Wu X, Pang K, et al. FOXG1 expression shows correlation with neuronal differentiation in cerebellar development, aggressive phenotype in medulloblastomas, and survival in a xenograft model of medulloblastoma. Hum Pathol. 2015;46:1859-71 pubmed publisher
  • immunocytochemistry; mouse; 1:1000; fig 2e
Choi H, Kim J, Hong Y, Song H, Seo H, Do J. In vivo reprogrammed pluripotent stem cells from teratomas share analogous properties with their in vitro counterparts. Sci Rep. 2015;5:13559 pubmed publisher
  • immunocytochemistry; mouse; 1:50; fig 3
Wang J, Zhang Y, Hou J, Qian X, Zhang H, Zhang Z, et al. Ube2s regulates Sox2 stability and mouse ES cell maintenance. Cell Death Differ. 2016;23:393-404 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:250; fig s3
Cases O, Joseph A, Obry A, Santin M, Ben Yacoub S, Pâques M, et al. Foxg1-Cre Mediated Lrp2 Inactivation in the Developing Mouse Neural Retina, Ciliary and Retinal Pigment Epithelia Models Congenital High Myopia. PLoS ONE. 2015;10:e0129518 pubmed publisher
  • immunocytochemistry; mouse; 1:500; fig 1e
Szlachcic W, Switonski P, Krzyzosiak W, Figlerowicz M, Figiel M. Huntington disease iPSCs show early molecular changes in intracellular signaling, the expression of oxidative stress proteins and the p53 pathway. Dis Model Mech. 2015;8:1047-57 pubmed publisher
  • immunocytochemistry; mouse
  • immunocytochemistry; human; 1:100-1:500; fig 5c
Petroni M, Sardina F, Heil C, Sahún Roncero M, Colicchia V, Veschi V, et al. The MRN complex is transcriptionally regulated by MYCN during neural cell proliferation to control replication stress. Cell Death Differ. 2016;23:197-206 pubmed publisher
  • immunocytochemistry; human; 1:100; fig 2
Lenzi J, De Santis R, de Turris V, Morlando M, Laneve P, Calvo A, et al. ALS mutant FUS proteins are recruited into stress granules in induced pluripotent stem cell-derived motoneurons. Dis Model Mech. 2015;8:755-66 pubmed publisher
  • immunocytochemistry; human; 1:200; fig 2
Chen H, Aksoy I, Gonnot F, Osteil P, Aubry M, Hamela C, et al. Reinforcement of STAT3 activity reprogrammes human embryonic stem cells to naive-like pluripotency. Nat Commun. 2015;6:7095 pubmed publisher
  • immunocytochemistry; human; 1:100; fig 1
Sun Y, Florer J, Mayhew C, Jia Z, Zhao Z, Xu K, et al. Properties of neurons derived from induced pluripotent stem cells of Gaucher disease type 2 patient fibroblasts: potential role in neuropathology. PLoS ONE. 2015;10:e0118771 pubmed publisher
  • immunohistochemistry; Paroedura; 1:200
  • immunohistochemistry; Chinese softshell turtle; 1:200
Nomura T, Yamashita W, Gotoh H, Ono K. Genetic manipulation of reptilian embryos: toward an understanding of cortical development and evolution. Front Neurosci. 2015;9:45 pubmed publisher
  • flow cytometry; mouse; 1:100; loading ...; fig 4b
  • immunocytochemistry; mouse; 1:100; loading ...; fig 6a
Serrano Pérez M, Fernández M, Neria F, Berjón Otero M, Doncel Pérez E, Cano E, et al. NFAT transcription factors regulate survival, proliferation, migration, and differentiation of neural precursor cells. Glia. 2015;63:987-1004 pubmed publisher
  • immunohistochemistry; mouse
Braude J, Vijayakumar S, Baumgarner K, Laurine R, Jones T, Jones S, et al. Deletion of Shank1 has minimal effects on the molecular composition and function of glutamatergic afferent postsynapses in the mouse inner ear. Hear Res. 2015;321:52-64 pubmed publisher
  • immunocytochemistry; domestic sheep; 10 ug/ml; loading ...; fig 2
German S, Campbell K, Thornton E, McLachlan G, Sweetman D, Alberio R. Ovine induced pluripotent stem cells are resistant to reprogramming after nuclear transfer. Cell Reprogram. 2015;17:19-27 pubmed publisher
  • immunocytochemistry; mouse; 1:200
Liu J, Bain L. Arsenic inhibits hedgehog signaling during P19 cell differentiation. Toxicol Appl Pharmacol. 2014;281:243-53 pubmed publisher
  • immunocytochemistry; human; 1:200
Shimamoto A, Kagawa H, Zensho K, Sera Y, Kazuki Y, Osaki M, et al. Reprogramming suppresses premature senescence phenotypes of Werner syndrome cells and maintains chromosomal stability over long-term culture. PLoS ONE. 2014;9:e112900 pubmed publisher
  • immunohistochemistry - frozen section; human; 1:200
Liu W, Edin F, Atturo F, Rieger G, Löwenheim H, Senn P, et al. The pre- and post-somatic segments of the human type I spiral ganglion neurons--structural and functional considerations related to cochlear implantation. Neuroscience. 2015;284:470-82 pubmed publisher
  • immunohistochemistry - frozen section; rat; 1:100
  • western blot; rat; 1:100
McLean N, Popescu B, Gordon T, Zochodne D, Verge V. Delayed nerve stimulation promotes axon-protective neurofilament phosphorylation, accelerates immune cell clearance and enhances remyelination in vivo in focally demyelinated nerves. PLoS ONE. 2014;9:e110174 pubmed publisher
  • immunocytochemistry; rat; 1:100
Teh D, Ishizuka T, Yawo H. Regulation of later neurogenic stages of adult-derived neural stem/progenitor cells by L-type Ca2+ channels. Dev Growth Differ. 2014;56:583-94 pubmed publisher
  • western blot; human; 1:250
Jha B, Rao M, Malik N. Motor neuron differentiation from pluripotent stem cells and other intermediate proliferative precursors that can be discriminated by lineage specific reporters. Stem Cell Rev. 2015;11:194-204 pubmed publisher
  • immunocytochemistry; mouse
Kamishibahara Y, Kawaguchi H, Shimizu N. Promotion of mouse embryonic stem cell differentiation by Rho kinase inhibitor Y-27632. Neurosci Lett. 2014;579:58-63 pubmed publisher
  • immunocytochemistry; mouse; 1:500
Torrado E, Gomes C, Santos G, Fernandes A, Brites D, Falcão A. Directing mouse embryonic neurosphere differentiation toward an enriched neuronal population. Int J Dev Neurosci. 2014;37:94-9 pubmed publisher
  • immunocytochemistry; human; 1:100
Muchkaeva I, Dashinimaev E, Artyuhov A, Myagkova E, Vorotelyak E, Yegorov Y, et al. Generation of iPS Cells from Human Hair Follice Dermal Papilla Cells. Acta Naturae. 2014;6:45-53 pubmed
  • immunocytochemistry; mouse; 1:600
Donai K, Inagaki A, So K, Kuroda K, Sone H, Kobayashi M, et al. Low-molecular-weight inhibitors of cell differentiation enable efficient growth of mouse iPS cells under feeder-free conditions. Cytotechnology. 2015;67:191-7 pubmed publisher
  • immunocytochemistry; mouse; 1:300
Lu T, Aron L, Zullo J, Pan Y, Kim H, Chen Y, et al. REST and stress resistance in ageing and Alzheimer's disease. Nature. 2014;507:448-54 pubmed publisher
  • In-Cell Western; mouse; 1:1000
  • immunohistochemistry - frozen section; mouse; 1:1000
Zhang P, Wu C, Liu N, Niu L, Yan Z, Feng Y, et al. Protocadherin 11 x regulates differentiation and proliferation of neural stem cell in vitro and in vivo. J Mol Neurosci. 2014;54:199-210 pubmed publisher
  • immunocytochemistry; mouse; 1:500
Ono T, Suzuki Y, Kato Y, Fujita R, Araki T, Yamashita T, et al. A single-cell and feeder-free culture system for monkey embryonic stem cells. PLoS ONE. 2014;9:e88346 pubmed publisher
  • immunohistochemistry - frozen section; rat; 1:1000
Sun F, Zhou K, Wang S, Liang P, Zhu M, Qiu J. Expression patterns of atrial natriuretic peptide and its receptors within the cochlear spiral ganglion of the postnatal rat. Hear Res. 2014;309:103-12 pubmed publisher
  • immunohistochemistry - frozen section; rat; 1:200
  • western blot; rat; 1:200
Nakajima T, Yanagihara M, Nishii H. Temporal and regional patterns of Smad activation in the rat hippocampus following global ischemia. J Neurol Sci. 2014;337:25-37 pubmed publisher
  • immunocytochemistry; human; 1:200
Hu Y, Ru N, Xiao H, Chaturbedi A, Hoa N, Tian X, et al. Tumor-specific chromosome mis-segregation controls cancer plasticity by maintaining tumor heterogeneity. PLoS ONE. 2013;8:e80898 pubmed publisher
  • immunocytochemistry; human; 1:100
Stover A, Brick D, Nethercott H, Banuelos M, Sun L, O Dowd D, et al. Process-based expansion and neural differentiation of human pluripotent stem cells for transplantation and disease modeling. J Neurosci Res. 2013;91:1247-62 pubmed publisher
  • immunohistochemistry; human; 1:200
Shintaku M, Yoneda H, Hirato J, Nagaishi M, Okabe H. Gliosarcoma with ependymal and PNET-like differentiation. Clin Neuropathol. 2013;32:508-14 pubmed publisher
  • immunocytochemistry; human; 1:200; fig 6
Hou P, Chuang C, Kao C, Chou S, Stone L, Ho H, et al. LHX2 regulates the neural differentiation of human embryonic stem cells via transcriptional modulation of PAX6 and CER1. Nucleic Acids Res. 2013;41:7753-70 pubmed publisher
  • immunocytochemistry; human; 1:400
  • western blot; human; 1:2000
Kao C, Hsu Y, Liu J, Lee D, Chung Y, Chiu I. The mood stabilizer valproate activates human FGF1 gene promoter through inhibiting HDAC and GSK-3 activities. J Neurochem. 2013;126:4-18 pubmed publisher
  • immunohistochemistry - frozen section; African green monkey; 1:100
Samaranch L, Salegio E, San Sebastián W, Kells A, Bringas J, Forsayeth J, et al. Strong cortical and spinal cord transduction after AAV7 and AAV9 delivery into the cerebrospinal fluid of nonhuman primates. Hum Gene Ther. 2013;24:526-32 pubmed publisher
  • immunohistochemistry - frozen section; mouse
Xu J, Nonogaki M, Madhira R, Ma H, Hermanson O, Kioussi C, et al. Population-specific regulation of Chmp2b by Lbx1 during onset of synaptogenesis in lateral association interneurons. PLoS ONE. 2012;7:e48573 pubmed publisher
  • immunohistochemistry - frozen section; dogs; 1:300
  • immunocytochemistry; dogs; 1:300
Walton R, Parmentier T, Wolfe J. Postnatal neural precursor cell regions in the rostral subventricular zone, hippocampal subgranular zone and cerebellum of the dog (Canis lupus familiaris). Histochem Cell Biol. 2013;139:415-29 pubmed publisher
  • immunocytochemistry; rhesus macaque; 1:500
Putkhao K, Kocerha J, Cho I, Yang J, Parnpai R, Chan A. Pathogenic cellular phenotypes are germline transmissible in a transgenic primate model of Huntington's disease. Stem Cells Dev. 2013;22:1198-205 pubmed publisher
  • immunocytochemistry; rat; 1:500
  • western blot; rat
Liu Y, Chen Y, Lu X, Wang Y, Duan Y, Cheng C, et al. SCYL1BP1 modulates neurite outgrowth and regeneration by regulating the Mdm2/p53 pathway. Mol Biol Cell. 2012;23:4506-14 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:2000
Espana A, Clotman F. Onecut transcription factors are required for the second phase of development of the A13 dopaminergic nucleus in the mouse. J Comp Neurol. 2012;520:1424-41 pubmed publisher
  • western blot; pigs
Yun Hong Y, Chih Fan C, Chia Wei C, Yen Chung C. A study of the spatial protein organization of the postsynaptic density isolated from porcine cerebral cortex and cerebellum. Mol Cell Proteomics. 2011;10:M110.007138 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:50
Kawano J, Tanizawa Y, Shinoda K. Wolfram syndrome 1 (Wfs1) gene expression in the normal mouse visual system. J Comp Neurol. 2008;510:1-23 pubmed publisher
Tsuchiya K, Nakajima S, Hosojima S, Thi Nguyen D, Hattori T, Manh Le T, et al. Caspase-1 initiates apoptosis in the absence of gasdermin D. Nat Commun. 2019;10:2091 pubmed publisher
Lee W, Mukha D, Aizenshtein E, Shlomi T. Spatial-fluxomics provides a subcellular-compartmentalized view of reductive glutamine metabolism in cancer cells. Nat Commun. 2019;10:1351 pubmed publisher
Mazor G, Levin L, Picard D, Ahmadov U, Caren H, Borkhardt A, et al. The lncRNA TP73-AS1 is linked to aggressiveness in glioblastoma and promotes temozolomide resistance in glioblastoma cancer stem cells. Cell Death Dis. 2019;10:246 pubmed publisher
Beldick S, Hong J, Altamentova S, Khazaei M, Hundal A, Zavvarian M, et al. Severe-combined immunodeficient rats can be used to generate a model of perinatal hypoxic-ischemic brain injury to facilitate studies of engrafted human neural stem cells. PLoS ONE. 2018;13:e0208105 pubmed publisher
Choi S, Kim Y, Park Y, Yang H, Jeong P, Cha J, et al. Novel crosstalk between Vps26a and Nox4 signaling during neurogenesis. Cell Death Differ. 2018;: pubmed publisher
Srikanth P, Lagomarsino V, PEARSE R, Liao M, Ghosh S, Nehme R, et al. Convergence of independent DISC1 mutations on impaired neurite growth via decreased UNC5D expression. Transl Psychiatry. 2018;8:245 pubmed publisher
Kim E, Hwang S, Yoon J, Kim H, Lee G, Hyun S. Isolation and characterization of GFAP-positive porcine neural stem/progenitor cells derived from a GFAP-CreERT2 transgenic piglet. BMC Vet Res. 2018;14:331 pubmed publisher
Parker S, Moutal A, Cai S, Chandrasekaran S, Roman M, Koshy A, et al. High Fidelity Cryopreservation and Recovery of Primary Rodent Cortical Neurons. Eneuro. 2018;5: pubmed publisher
Wang S, Liu Z, Ye Y, Li B, Liu T, Zhang W, et al. Ectopic hTERT expression facilitates reprograming of fibroblasts derived from patients with Werner syndrome as a WS cellular model. Cell Death Dis. 2018;9:923 pubmed publisher
Persoon C, Moro A, Nassal J, Farina M, Broeke J, Arora S, et al. Pool size estimations for dense-core vesicles in mammalian CNS neurons. EMBO J. 2018;37: pubmed publisher
Xia W, Su L, Jiao J. Cold-induced protein RBM3 orchestrates neurogenesis via modulating Yap mRNA stability in cold stress. J Cell Biol. 2018;217:3464-3479 pubmed publisher
Ma W, Jin G, Gehret P, Chada N, Suh W. A Novel Cell Penetrating Peptide for the Differentiation of Human Neural Stem Cells. Biomolecules. 2018;8: pubmed publisher
Xiao J, Li X, Liu L, Wang G, Hao S, Dong H, et al. The association of semaphorin 5A with lymph node metastasis and adverse prognosis in cervical cancer. Cancer Cell Int. 2018;18:87 pubmed publisher
Tanaka N, Cortese G, Barrientos R, Maier S, Patterson S. Aging and an Immune Challenge Interact to Produce Prolonged, but Not Permanent, Reductions in Hippocampal L-LTP and mBDNF in a Rodent Model with Features of Delirium. Eneuro. 2018;5: pubmed publisher
Shafa M, Yang F, Fellner T, Rao M, Baghbaderani B. Human-Induced Pluripotent Stem Cells Manufactured Using a Current Good Manufacturing Practice-Compliant Process Differentiate Into Clinically Relevant Cells From Three Germ Layers. Front Med (Lausanne). 2018;5:69 pubmed publisher
Liu W, Molnár M, Garnham C, Benav H, Rask Andersen H. Macrophages in the Human Cochlea: Saviors or Predators-A Study Using Super-Resolution Immunohistochemistry. Front Immunol. 2018;9:223 pubmed publisher
Abraham M, Rasti M, Bauer P, Lam T. Leptin enhances hypothalamic lactate dehydrogenase A (LDHA)-dependent glucose sensing to lower glucose production in high-fat-fed rats. J Biol Chem. 2018;293:4159-4166 pubmed publisher
Stamou M, Grodzki A, van Oostrum M, Wollscheid B, Lein P. Fc gamma receptors are expressed in the developing rat brain and activate downstream signaling molecules upon cross-linking with immune complex. J Neuroinflammation. 2018;15:7 pubmed publisher
Sepp M, Vihma H, Nurm K, Urb M, Page S, Roots K, et al. The Intellectual Disability and Schizophrenia Associated Transcription Factor TCF4 Is Regulated by Neuronal Activity and Protein Kinase A. J Neurosci. 2017;37:10516-10527 pubmed publisher
Boubakar L, Falk J, Ducuing H, Thoinet K, Reynaud F, Derrington E, et al. Molecular Memory of Morphologies by Septins during Neuron Generation Allows Early Polarity Inheritance. Neuron. 2017;95:834-851.e5 pubmed publisher
Miele E, Po A, Begalli F, Antonucci L, Mastronuzzi A, Marras C, et al. β-arrestin1-mediated acetylation of Gli1 regulates Hedgehog/Gli signaling and modulates self-renewal of SHH medulloblastoma cancer stem cells. BMC Cancer. 2017;17:488 pubmed publisher
Li Y, Jiao J. Histone chaperone HIRA regulates neural progenitor cell proliferation and neurogenesis via β-catenin. J Cell Biol. 2017;216:1975-1992 pubmed publisher
Lin M, Cheng X, Tammineni P, Xie Y, Zhou B, Cai Q, et al. Releasing Syntaphilin Removes Stressed Mitochondria from Axons Independent of Mitophagy under Pathophysiological Conditions. Neuron. 2017;94:595-610.e6 pubmed publisher
Francius C, Hidalgo Figueroa M, Debrulle S, Pelosi B, Rucchin V, Ronellenfitch K, et al. Vsx1 Transiently Defines an Early Intermediate V2 Interneuron Precursor Compartment in the Mouse Developing Spinal Cord. Front Mol Neurosci. 2016;9:145 pubmed publisher
Allodi I, Comley L, Nichterwitz S, Nizzardo M, Simone C, Benitez J, et al. Differential neuronal vulnerability identifies IGF-2 as a protective factor in ALS. Sci Rep. 2016;6:25960 pubmed publisher
Radford H, Moreno J, Verity N, Halliday M, Mallucci G. PERK inhibition prevents tau-mediated neurodegeneration in a mouse model of frontotemporal dementia. Acta Neuropathol. 2015;130:633-42 pubmed publisher
Balasubramaniyan V, Vaillant B, Wang S, Gumin J, Butalid M, Sai K, et al. Aberrant mesenchymal differentiation of glioma stem-like cells: implications for therapeutic targeting. Oncotarget. 2015;6:31007-17 pubmed publisher
Metzakopian E, Bouhali K, Alvarez Saavedra M, Whitsett J, Picketts D, Ang S. Genome-wide characterisation of Foxa1 binding sites reveals several mechanisms for regulating neuronal differentiation in midbrain dopamine cells. Development. 2015;142:1315-24 pubmed publisher
Mellai M, Piazzi A, Casalone C, Grifoni S, Melcarne A, Annovazzi L, et al. Astroblastoma: beside being a tumor entity, an occasional phenotype of astrocytic gliomas?. Onco Targets Ther. 2015;8:451-60 pubmed publisher
Liu W, Atturo F, Aldaya R, Santi P, Cureoglu S, Obwegeser S, et al. Macromolecular organization and fine structure of the human basilar membrane - RELEVANCE for cochlear implantation. Cell Tissue Res. 2015;360:245-62 pubmed publisher
Dai R, Rossello R, Chen C, Kessler J, Davison I, Hochgeschwender U, et al. Maintenance and neuronal differentiation of chicken induced pluripotent stem-like cells. Stem Cells Int. 2014;2014:182737 pubmed publisher
Mo C, Wu F, Tai K, Chang W, Chang K, Kuo H, et al. Loss of non-coding RNA expression from the DLK1-DIO3 imprinted locus correlates with reduced neural differentiation potential in human embryonic stem cell lines. Stem Cell Res Ther. 2015;6:1 pubmed publisher
Lee H, Lee J, Park M, Hong Y, Marti H, Kim H, et al. Pathological roles of the VEGF/SphK pathway in Niemann-Pick type C neurons. Nat Commun. 2014;5:5514 pubmed publisher
Edin F, Liu W, Li H, Atturo F, Magnusson P, Rask Andersen H. 3-D gel culture and time-lapse video microscopy of the human vestibular nerve. Acta Otolaryngol. 2014;134:1211-8 pubmed publisher
Di Noto G, Chiarini M, Paolini L, Mazzoldi E, Giustini V, Radeghieri A, et al. Immunoglobulin Free Light Chains and GAGs Mediate Multiple Myeloma Extracellular Vesicles Uptake and Secondary NfκB Nuclear Translocation. Front Immunol. 2014;5:517 pubmed publisher
Sadeghi S, Pyott S, Yu Z, Glowatzki E. Glutamatergic signaling at the vestibular hair cell calyx synapse. J Neurosci. 2014;34:14536-50 pubmed publisher
Ding D, Xu L, Xu H, Li X, Liang Q, Zhao Y, et al. Mash1 efficiently reprograms rat astrocytes into neurons. Neural Regen Res. 2014;9:25-32 pubmed publisher
Uc A, Olivier A, Griffin M, Meyerholz D, Yao J, Abu El Haija M, et al. Glycaemic regulation and insulin secretion are abnormal in cystic fibrosis pigs despite sparing of islet cell mass. Clin Sci (Lond). 2015;128:131-42 pubmed publisher
Han D, Choi M, Jung K, Kim N, Kim S, Chai J, et al. Global transcriptome profiling of genes that are differentially regulated during differentiation of mouse embryonic neural stem cells into astrocytes. J Mol Neurosci. 2015;55:109-125 pubmed publisher
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product information
Catalog Number :
MAB1637
Subcategory :
Neuroscience
Product Name :
Anti-Tubulin Antibody, beta III isoform, CT, clone TU-20 (Similar to TUJ1)
Product Type :
Antibodies
Clonality :
Monoclonal Antibody
Gene ID :
Q13509
Host Name :
Mouse
Antigen :
Tubulin
Clone :
TU-20 (Similar to TUJ1)
Conjugate :
Ascites
Isotype :
IgG1
Product Description :
Anti-Tubulin Antibody, beta III isoform, CT, clone TU-20 (Similar to TUJ1)
Cross Reactivity :
Avian;Bovine;Human;Mouse;Monkey;Pig;Rat;Sheep
Background :
Tubulin is one of several members of a small family of globular proteins. The most common members of the tubulin family are α-tubulin and β-tubulin, the proteins which makes up microtubules. Each has a molecular weight of approximately 55 kDa. Microtubules are assembled from dimers of α- and β-tubulin. These subunits are slightly acidic with an isoelectric point between 5.2 and 5.8. Tubulin was long thought to be specific to eukaryotes. Recently, however, the prokaryotic cell division protein FtsZ was shown to be evolutionarily related to tubulin.
ALT Names :
Tubulin beta-III;tubulin, beta 3;tubulin, beta, 4
Immunogen :
A synthetic peptide corresponding to amino acids 443-450 (ESESQGPK) of human class III beta-tubulin conjugated to KLH.
Specificity :
The antibody reacts with the C-terminus of the neuron specific beta III isoform of tubulin. Does not identify beta tubulin found in glial cells.
Package Size :
100 µL
Uses :
ELISA;Immunocytochemistry;Immunohistochemistry;Immunohistochemistry (Paraffin);Immunoprecipitation;Western Blotting
Storage :
Stable for 1 year at -20°C in undiluted aliquots from date of receipt. Handling Recommendations: Upon first thaw, and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
more info or order :
company information
EMD Millipore
290 Concord Road
Billerica, Massachusetts 01821
bioscienceshelp@emdchemical.com
https://www.emdmillipore.com
888-854-3417
headquarters: United States
EMD Millipore is the Life Science division of Merck KGaA of Darmstadt, Germany

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