| Published Application/Species/Sample/Dilution | Reference |
|---|
- immunocytochemistry; mouse; 1:100; loading ...; fig 8a
| Moon H, Hippenmeyer S, Luo L, Wynshaw Boris A. LIS1 determines cleavage plane positioning by regulating actomyosin-mediated cell membrane contractility. elife. 2020;9: pubmed publisher |
- western blot; mouse; 1:500; loading ...; fig 4n
| Even A, Morelli G, Broix L, Scaramuzzino C, Turchetto S, Gladwyn Ng I, et al. ATAT1-enriched vesicles promote microtubule acetylation via axonal transport. Sci Adv. 2019;5:eaax2705 pubmed publisher |
- western blot; mouse; 1:2000; loading ...; fig s6a
| Singh V, Erady C, Balasubramanian N. Cell-matrix adhesion controls Golgi organization and function through Arf1 activation in anchorage-dependent cells. J Cell Sci. 2018;131: pubmed publisher |
- immunoprecipitation; mouse; 1:300; loading ...; fig 2c
- western blot; mouse; loading ...; fig 2c
| Han W, Wang H, Li J, Zhang S, Lu W. Ferric Chelate Reductase 1 Like Protein (FRRS1L) Associates with Dynein Vesicles and Regulates Glutamatergic Synaptic Transmission. Front Mol Neurosci. 2017;10:402 pubmed publisher |
- western blot; human; loading ...; fig 5a
| Connell M, Chen H, Jiang J, Kuan C, Fotovati A, Chu T, et al. HMMR acts in the PLK1-dependent spindle positioning pathway and supports neural development. elife. 2017;6: pubmed publisher |
- immunocytochemistry; human; 1:100; loading ...; fig s10a
| Magescas J, Sengmanivong L, Viau A, Mayeux A, Dang T, Burtin M, et al. Spindle pole cohesion requires glycosylation-mediated localization of NuMA. Sci Rep. 2017;7:1474 pubmed publisher |
- western blot; mouse; 1:500; fig 1b
| Hinckelmann M, Virlogeux A, Niehage C, Poujol C, Choquet D, Hoflack B, et al. Self-propelling vesicles define glycolysis as the minimal energy machinery for neuronal transport. Nat Commun. 2016;7:13233 pubmed publisher |
- western blot; pigs ; 1:1000; loading ...; fig 4c
| Schroeder C, Vale R. Assembly and activation of dynein-dynactin by the cargo adaptor protein Hook3. J Cell Biol. 2016;214:309-18 pubmed publisher |
- immunohistochemistry; mouse; 1:200; loading ...; fig 5a
| Sadleir K, Kandalepas P, Buggia Prevot V, Nicholson D, Thinakaran G, Vassar R. Presynaptic dystrophic neurites surrounding amyloid plaques are sites of microtubule disruption, BACE1 elevation, and increased Aβ generation in Alzheimer's disease. Acta Neuropathol. 2016;132:235-56 pubmed publisher |
- immunocytochemistry; human; 1:150
- western blot; human; 1:1000; fig 2
| Hori A, Barnouin K, Snijders A, Toda T. A non-canonical function of Plk4 in centriolar satellite integrity and ciliogenesis through PCM1 phosphorylation. EMBO Rep. 2016;17:326-37 pubmed publisher |
- immunocytochemistry; human; fig 4
| Jovasevic V, Naghavi M, Walsh D. Microtubule plus end-associated CLIP-170 initiates HSV-1 retrograde transport in primary human cells. J Cell Biol. 2015;211:323-37 pubmed publisher |
- immunocytochemistry; human; 1:500; fig 5
- western blot; human; 1:1000; fig 5
| Malikov V, da Silva E, Jovasevic V, Bennett G, de Souza Aranha Vieira D, Schulte B, et al. HIV-1 capsids bind and exploit the kinesin-1 adaptor FEZ1 for inward movement to the nucleus. Nat Commun. 2015;6:6660 pubmed publisher |
| Brandstaetter H, Kruppa A, Buss F. Huntingtin is required for ER-to-Golgi transport and for secretory vesicle fusion at the plasma membrane. Dis Model Mech. 2014;7:1335-40 pubmed publisher |
- western blot; human; fig 2
| Asante D, Stevenson N, Stephens D. Subunit composition of the human cytoplasmic dynein-2 complex. J Cell Sci. 2014;127:4774-87 pubmed publisher |
| Wong Y, Holzbaur E. The regulation of autophagosome dynamics by huntingtin and HAP1 is disrupted by expression of mutant huntingtin, leading to defective cargo degradation. J Neurosci. 2014;34:1293-305 pubmed publisher |
- blocking or activating experiments; human
| Diagouraga B, Grichine A, Fertin A, Wang J, Khochbin S, Sadoul K. Motor-driven marginal band coiling promotes cell shape change during platelet activation. J Cell Biol. 2014;204:177-85 pubmed publisher |
- western blot; African green monkey
- western blot; mouse
| Perlson E, Hendricks A, Lazarus J, Ben Yaakov K, Gradus T, Tokito M, et al. Dynein interacts with the neural cell adhesion molecule (NCAM180) to tether dynamic microtubules and maintain synaptic density in cortical neurons. J Biol Chem. 2013;288:27812-24 pubmed publisher |
- immunoprecipitation; mouse
- western blot; mouse
| Zhang J, Twelvetrees A, Lazarus J, Blasier K, Yao X, Inamdar N, et al. Establishing a novel knock-in mouse line for studying neuronal cytoplasmic dynein under normal and pathologic conditions. Cytoskeleton (Hoboken). 2013;70:215-27 pubmed publisher |
| Poon J, Fries A, Wessel G, Yajima M. Evolutionary modification of AGS protein contributes to formation of micromeres in sea urchins. Nat Commun. 2019;10:3779 pubmed publisher |
| Rosas Salvans M, Scrofani J, Modol A, Vernos I. DnaJB6 is a RanGTP-regulated protein required for microtubule organization during mitosis. J Cell Sci. 2019;132: pubmed publisher |
| Williamson C, Donaldson J. Arf6, JIP3, and dynein shape and mediate macropinocytosis. Mol Biol Cell. 2019;30:1477-1489 pubmed publisher |
| Neubauer H, Tea M, Zebol J, Gliddon B, Stefanidis C, Moretti P, et al. Cytoplasmic dynein regulates the subcellular localization of sphingosine kinase 2 to elicit tumor-suppressive functions in glioblastoma. Oncogene. 2019;38:1151-1165 pubmed publisher |
| Vuolo L, Stevenson N, Heesom K, Stephens D. Dynein-2 intermediate chains play crucial but distinct roles in primary cilia formation and function. elife. 2018;7: pubmed publisher |
| di Pietro F, Valon L, Li Y, Goïame R, Genovesio A, Morin X. An RNAi Screen in a Novel Model of Oriented Divisions Identifies the Actin-Capping Protein Z ? as an Essential Regulator of Spindle Orientation. Curr Biol. 2017;27:2452-2464.e8 pubmed publisher |
| Zheng J, Gao M, Huynh N, Tindell S, Vo H, McDonald W, et al. In vivo mapping of a dynamic ribonucleoprotein granule interactome in early Drosophila embryos. FEBS Open Bio. 2016;6:1248-1256 pubmed publisher |
| Neisch A, Neufeld T, Hays T. A STRIPAK complex mediates axonal transport of autophagosomes and dense core vesicles through PP2A regulation. J Cell Biol. 2017;216:441-461 pubmed publisher |
| Gao F, Shi L, Hines T, Hebbar S, Neufeld K, Smith D. Insulin signaling regulates a functional interaction between adenomatous polyposis coli and cytoplasmic dynein. Mol Biol Cell. 2017;28:587-599 pubmed publisher |
| Chanduri M, Rai A, Malla A, Wu M, Fiedler D, Mallik R, et al. Inositol hexakisphosphate kinase 1 (IP6K1) activity is required for cytoplasmic dynein-driven transport. Biochem J. 2016;473:3031-47 pubmed publisher |
| Lopes C, Aubert S, Bourgois Rocha F, Barnat M, Rego A, Déglon N, et al. Dominant-Negative Effects of Adult-Onset Huntingtin Mutations Alter the Division of Human Embryonic Stem Cells-Derived Neural Cells. PLoS ONE. 2016;11:e0148680 pubmed publisher |
| Schwarz D, Blower M. The calcium-dependent ribonuclease XendoU promotes ER network formation through local RNA degradation. J Cell Biol. 2014;207:41-57 pubmed publisher |
| Liu Y, Yuan Y, Sun J, Li J, Li Z, Chen N. Nigrostriatal dynein changes in A53T alpha-synuclein transgenic mice. F1000Res. 2014;3:68 pubmed publisher |
| Kong S, Du X, Du X, Peng C, Wu Y, Li H, et al. Dlic1 deficiency impairs ciliogenesis of photoreceptors by destabilizing dynein. Cell Res. 2013;23:835-50 pubmed publisher |
| Stowe T, Wilkinson C, Iqbal A, Stearns T. The centriolar satellite proteins Cep72 and Cep290 interact and are required for recruitment of BBS proteins to the cilium. Mol Biol Cell. 2012;23:3322-35 pubmed publisher |
| Fatima R. Drosophila Dynein intermediate chain gene, Dic61B, is required for spermatogenesis. PLoS ONE. 2011;6:e27822 pubmed publisher |
| Morel M, Héraud C, Nicaise C, Suain V, Brion J. Levels of kinesin light chain and dynein intermediate chain are reduced in the frontal cortex in Alzheimer's disease: implications for axoplasmic transport. Acta Neuropathol. 2012;123:71-84 pubmed publisher |
| Sanchez Varo R, Trujillo Estrada L, Sanchez Mejias E, Torres M, Baglietto Vargas D, Moreno Gonzalez I, et al. Abnormal accumulation of autophagic vesicles correlates with axonal and synaptic pathology in young Alzheimer's mice hippocampus. Acta Neuropathol. 2012;123:53-70 pubmed publisher |
| Cappello S, Monzo P, Vallee R. NudC is required for interkinetic nuclear migration and neuronal migration during neocortical development. Dev Biol. 2011;357:326-35 pubmed publisher |
| Rothwell W, Sullivan W. Commonly used reagents for visualizing Drosophila embryo structures. CSH Protoc. 2007;2007:pdb.ip44 pubmed publisher |
| Rishal I, Michaelevski I, Rozenbaum M, Shinder V, Medzihradszky K, Burlingame A, et al. Axoplasm isolation from peripheral nerve. Dev Neurobiol. 2010;70:126-33 pubmed publisher |
| Perlson E, Jeong G, Ross J, Dixit R, Wallace K, Kalb R, et al. A switch in retrograde signaling from survival to stress in rapid-onset neurodegeneration. J Neurosci. 2009;29:9903-17 pubmed publisher |
| Racedo S, Branzini M, Salamone D, Wojcik C, Rawe V, Niemann H. Dynamics of microtubules, motor proteins and 20S proteasomes during bovine oocyte IVM. Reprod Fertil Dev. 2009;21:304-12 pubmed |
| Nguyen C, M nger K. Human papillomavirus E7 protein deregulates mitosis via an association with nuclear mitotic apparatus protein 1. J Virol. 2009;83:1700-7 pubmed publisher |
| Nguyen C, McLaughlin Drubin M, Munger K. Delocalization of the microtubule motor Dynein from mitotic spindles by the human papillomavirus E7 oncoprotein is not sufficient for induction of multipolar mitoses. Cancer Res. 2008;68:8715-22 pubmed publisher |
| Mische S, He Y, Ma L, Li M, Serr M, Hays T. Dynein light intermediate chain: an essential subunit that contributes to spindle checkpoint inactivation. Mol Biol Cell. 2008;19:4918-29 pubmed publisher |
| Doering J, Kane K, Hsiao Y, Yao C, Shi B, Slowik A, et al. Species differences in the expression of Ahi1, a protein implicated in the neurodevelopmental disorder Joubert syndrome, with preferential accumulation to stigmoid bodies. J Comp Neurol. 2008;511:238-56 pubmed publisher |
| Toth C, Shim S, Wang J, Jiang Y, Neumayer G, Belzil C, et al. Ndel1 promotes axon regeneration via intermediate filaments. PLoS ONE. 2008;3:e2014 pubmed publisher |
| Chevalier Larsen E, Wallace K, Pennise C, Holzbaur E. Lysosomal proliferation and distal degeneration in motor neurons expressing the G59S mutation in the p150Glued subunit of dynactin. Hum Mol Genet. 2008;17:1946-55 pubmed publisher |
| Chen H, Yang J, Low P, Cheng J. Cholesterol level regulates endosome motility via Rab proteins. Biophys J. 2008;94:1508-20 pubmed |
| Jin Q, Ding W, Mulder K. Requirement for the dynein light chain km23-1 in a Smad2-dependent transforming growth factor-beta signaling pathway. J Biol Chem. 2007;282:19122-32 pubmed |
| Bergen J, Pun S. Evaluation of an LC8-binding peptide for the attachment of artificial cargo to dynein. Mol Pharm. 2007;4:119-28 pubmed |
| Sarkar S, Bananis E, Nath S, Anwer M, Wolkoff A, Murray J. PKCzeta is required for microtubule-based motility of vesicles containing the ntcp transporter. Traffic. 2006;7:1078-91 pubmed |
| Liu G, Ding W, Liu X, Mulder K. c-Fos is required for TGFbeta1 production and the associated paracrine migratory effects of human colon carcinoma cells. Mol Carcinog. 2006;45:582-93 pubmed |
| Motil J, Chan W, Dubey M, Chaudhury P, Pimenta A, Chylinski T, et al. Dynein mediates retrograde neurofilament transport within axons and anterograde delivery of NFs from perikarya into axons: regulation by multiple phosphorylation events. Cell Motil Cytoskeleton. 2006;63:266-86 pubmed |
| Betz R, Planko L, Eigelshoven S, Hanneken S, Pasternack S, Bussow H, et al. Loss-of-function mutations in the keratin 5 gene lead to Dowling-Degos disease. Am J Hum Genet. 2006;78:510-9 pubmed |
| Utton M, Noble W, Hill J, Anderton B, Hanger D. Molecular motors implicated in the axonal transport of tau and alpha-synuclein. J Cell Sci. 2005;118:4645-54 pubmed |
| Dzhindzhev N, Rogers S, Vale R, Ohkura H. Distinct mechanisms govern the localisation of Drosophila CLIP-190 to unattached kinetochores and microtubule plus-ends. J Cell Sci. 2005;118:3781-90 pubmed |
| Jin Q, Ding W, Staub C, Gao G, Tang Q, Mulder K. Requirement of km23 for TGFbeta-mediated growth inhibition and induction of fibronectin expression. Cell Signal. 2005;17:1363-72 pubmed |
| Quintyne N, Schroer T. Distinct cell cycle-dependent roles for dynactin and dynein at centrosomes. J Cell Biol. 2002;159:245-54 pubmed |
| Rusan N, Tulu U, Fagerstrom C, Wadsworth P. Reorganization of the microtubule array in prophase/prometaphase requires cytoplasmic dynein-dependent microtubule transport. J Cell Biol. 2002;158:997-1003 pubmed |
| Tai A, Chuang J, Sung C. Cytoplasmic dynein regulation by subunit heterogeneity and its role in apical transport. J Cell Biol. 2001;153:1499-509 pubmed |
