This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
EMD Millipore
other brands :
Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava
product type :
antibody
product name :
NMDAR1 Antibody, (all splice variants), clone R1JHL
catalog :
MAB1586
quantity :
15 µg
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
R1JHL

The same clone is also sold as:
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunoprecipitation
citations: 12
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; loading ...; fig 2c
Barad Z, Grattan D, Leitch B. NMDA Receptor Expression in the Thalamus of the Stargazer Model of Absence Epilepsy. Sci Rep. 2017;7:42926 pubmed publisher
  • western blot; mouse; fig 4
Rodríguez Muñoz M, Cortés Montero E, Pozo Rodrigálvarez A, Sánchez Blázquez P, Garzón Niño J. The ON:OFF switch, σ1R-HINT1 protein, controls GPCR-NMDA receptor cross-regulation: implications in neurological disorders. Oncotarget. 2015;6:35458-77 pubmed publisher
  • immunoprecipitation; mouse; fig 9
  • immunohistochemistry; mouse; fig 4
  • western blot; mouse; fig 6
Rodríguez Muñoz M, Sánchez Blázquez P, Herrero Labrador R, Martínez Murillo R, Merlos M, Vela J, et al. The σ1 receptor engages the redox-regulated HINT1 protein to bring opioid analgesia under NMDA receptor negative control. Antioxid Redox Signal. 2015;22:799-818 pubmed publisher
  • western blot; mouse; 1:500
Abrahao K, Ariwodola O, Butler T, Rau A, Skelly M, Carter E, et al. Locomotor sensitization to ethanol impairs NMDA receptor-dependent synaptic plasticity in the nucleus accumbens and increases ethanol self-administration. J Neurosci. 2013;33:4834-42 pubmed publisher
Sharma R, Al Saleem F, Puligedda R, Rattelle A, Lynch D, Dessain S. Membrane-bound and soluble forms of an NMDA receptor extracellular domain retain epitopes targeted in auto-immune encephalitis. BMC Biotechnol. 2018;18:41 pubmed publisher
Smith K, Rajgor D, Hanley J. Differential regulation of the Rac1 GTPase-activating protein (GAP) BCR during oxygen/glucose deprivation in hippocampal and cortical neurons. J Biol Chem. 2017;292:20173-20183 pubmed publisher
Qiu S, Lu Z, Levitt P. MET receptor tyrosine kinase controls dendritic complexity, spine morphogenesis, and glutamatergic synapse maturation in the hippocampus. J Neurosci. 2014;34:16166-79 pubmed publisher
Hänggi P, Makhro A, Gassmann M, Schmugge M, Goede J, Speer O, et al. Red blood cells of sickle cell disease patients exhibit abnormally high abundance of N-methyl D-aspartate receptors mediating excessive calcium uptake. Br J Haematol. 2014;167:252-64 pubmed publisher
Ye S, Riou M, Carvalho S, Paoletti P. Expanding the genetic code in Xenopus laevis oocytes. Chembiochem. 2013;14:230-5 pubmed publisher
Karakas E, Simorowski N, Furukawa H. Subunit arrangement and phenylethanolamine binding in GluN1/GluN2B NMDA receptors. Nature. 2011;475:249-53 pubmed publisher
Lee C, Gouaux E. Amino terminal domains of the NMDA receptor are organized as local heterodimers. PLoS ONE. 2011;6:e19180 pubmed publisher
Stevens H, Smith K, Maragnoli M, Fagel D, Borok E, Shanabrough M, et al. Fgfr2 is required for the development of the medial prefrontal cortex and its connections with limbic circuits. J Neurosci. 2010;30:5590-602 pubmed publisher
product information
Catalog Number :
MAB1586
Subcategory :
Neuroscience
Product Name :
Anti-NMDAR1 Antibody, (all splice variants), clone R1JHL
Product Type :
Antibodies
Clonality :
Monoclonal Antibody
Gene ID :
Q05586
Host Name :
Mouse
Antigen :
NMDAR1
Clone :
R1JHL
Conjugate :
Purified
Isotype :
Ig
Product Description :
Anti-NMDAR1 Antibody, (all splice variants), clone R1JHL
Cross Reactivity :
Human;Mouse;Rat
Immunogen :
Fusion protein of amino acids 1-564 from rat NR1.
Specificity :
NMDA receptor subunit 1 (all splice variants). No cross-reactivity observed with other NMDA receptor subunits. Recognizes a 103-116 kDa protein in rat brain hippocampal homogenate by immunoblot.
Package Size :
15 µg
Uses :
Western Blotting
Storage :
Maintain lyophilized material at -20°C for up to six months after date of receipt. After reconstitution, maintain at -20°C in undiluted aliquots for up to six months. Avoid repeated freeze/thaw cycles.
company information
EMD Millipore
290 Concord Road
Billerica, Massachusetts 01821
bioscienceshelp@emdchemical.com
https://www.emdmillipore.com
888-854-3417
headquarters: United States
EMD Millipore is the Life Science division of Merck KGaA of Darmstadt, Germany

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