product summary
company name :
EMD Millipore
other brands :
Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava
product type :
antibody
product name :
Oligodendrocytes Antibody, clone NS-1
catalog :
MAB1580
quantity :
100 μL
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
NS-1
reactivity :
human, mouse, rat
application :
immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
citations: 53
Published Application/Species/Sample/DilutionReference
  • immunocytochemistry; rat; fig 5b
Walters R, Medintz I, Delehanty J, Stewart M, Susumu K, Huston A, et al. The Role of Negative Charge in the Delivery of Quantum Dots to Neurons. ASN Neuro. 2015;7: pubmed publisher
  • immunohistochemistry - paraffin section; mouse
Luna Sánchez M, Díaz Casado E, Barca E, Tejada M, Montilla García Ã, Cobos E, et al. The clinical heterogeneity of coenzyme Q10 deficiency results from genotypic differences in the Coq9 gene. EMBO Mol Med. 2015;7:670-87 pubmed publisher
  • immunohistochemistry; mouse; 1:500
Jendresen C, Cui H, Zhang X, Vlodavsky I, Nilsson L, Li J. Overexpression of heparanase lowers the amyloid burden in amyloid-β precursor protein transgenic mice. J Biol Chem. 2015;290:5053-64 pubmed publisher
  • immunohistochemistry - frozen section; rat; 1:1000
Sevc J, Matiašová A, Kútna V, Daxnerova Z. Evidence that the central canal lining of the spinal cord contributes to oligodendrogenesis during postnatal development and adulthood in intact rats. J Comp Neurol. 2014;522:3194-207 pubmed publisher
  • immunohistochemistry - frozen section; rat; 1:5000
Harris N, Nogueira M, Verley D, Sutton R. Chondroitinase enhances cortical map plasticity and increases functionally active sprouting axons after brain injury. J Neurotrauma. 2013;30:1257-69 pubmed publisher
  • immunohistochemistry; human; 1:1000
Trabalza A, Georgiadis C, Eleftheriadou I, Hislop J, Ellison S, Karavassilis M, et al. Venezuelan equine encephalitis virus glycoprotein pseudotyping confers neurotropism to lentiviral vectors. Gene Ther. 2013;20:723-32 pubmed publisher
  • immunohistochemistry - frozen section; rat; 1:500
  • immunocytochemistry; rat; 1:1000
Madhavan L, Daley B, Paumier K, Collier T. Transplantation of subventricular zone neural precursors induces an endogenous precursor cell response in a rat model of Parkinson's disease. J Comp Neurol. 2009;515:102-15 pubmed publisher
  • immunohistochemistry - frozen section; rat; 1:10000
Sakakibara S, Nakadate K, Tanaka Nakadate S, Yoshida K, Nogami S, Shirataki H, et al. Developmental and spatial expression pattern of alpha-taxilin in the rat central nervous system. J Comp Neurol. 2008;511:65-80 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:100000
Kawano J, Tanizawa Y, Shinoda K. Wolfram syndrome 1 (Wfs1) gene expression in the normal mouse visual system. J Comp Neurol. 2008;510:1-23 pubmed publisher
Ha S, Jeong S, Yi K, Chu J, Kim S, Kim E, et al. Autophagy Mediates Astrogenesis in Adult Hippocampal Neural Stem Cells. Exp Neurobiol. 2019;28:229-246 pubmed publisher
Takamori Y, Hirahara Y, Wakabayashi T, Mori T, Koike T, Kataoka Y, et al. Differential expression of nuclear lamin subtypes in the neural cells of the adult rat cerebral cortex. IBRO Rep. 2018;5:99-109 pubmed publisher
Dent K, Christie K, Bye N, Basrai H, Turbic A, Habgood M, et al. Oligodendrocyte birth and death following traumatic brain injury in adult mice. PLoS ONE. 2015;10:e0121541 pubmed publisher
Najafzadeh N, Nobakht M, Pourheydar B, Golmohammadi M. Rat hair follicle stem cells differentiate and promote recovery following spinal cord injury. Neural Regen Res. 2013;8:3365-72 pubmed publisher
Vanderveen N, Paran C, Appelhans A, Krasinkiewicz J, Lemons R, Appelman H, et al. Marmosets as a preclinical model for testing "off-label" use of doxycycline to turn on Flt3L expression from high-capacity adenovirus vectors. Mol Ther Methods Clin Dev. 2014;1: pubmed
Jensen P, Heimberg M, Ducray A, Widmer H, Meyer M. Expression of trefoil factor 1 in the developing and adult rat ventral mesencephalon. PLoS ONE. 2013;8:e76592 pubmed publisher
Kempf A, Montani L, Petrinovic M, Schroeter A, Weinmann O, Patrignani A, et al. Upregulation of axon guidance molecules in the adult central nervous system of Nogo-A knockout mice restricts neuronal growth and regeneration. Eur J Neurosci. 2013;38:3567-79 pubmed publisher
Bonner J, Haas C, Fischer I. Preparation of neural stem cells and progenitors: neuronal production and grafting applications. Methods Mol Biol. 2013;1078:65-88 pubmed publisher
Franco Rodríguez N, Dueñas Jiménez J, De la Torre Valdovinos B, López Ruiz J, Hernandez Hernandez L, Dueñas Jiménez S. Tamoxifen favoured the rat sensorial cortex regeneration after a penetrating brain injury. Brain Res Bull. 2013;98:64-75 pubmed publisher
Trazzi S, Fuchs C, Valli E, Perini G, Bartesaghi R, Ciani E. The amyloid precursor protein (APP) triplicated gene impairs neuronal precursor differentiation and neurite development through two different domains in the Ts65Dn mouse model for Down syndrome. J Biol Chem. 2013;288:20817-29 pubmed publisher
Grinberg Y, Dibbern M, Levasseur V, Kraig R. Insulin-like growth factor-1 abrogates microglial oxidative stress and TNF-? responses to spreading depression. J Neurochem. 2013;126:662-72 pubmed publisher
Wong A, Xiao J, Kemper D, Kilpatrick T, Murray S. Oligodendroglial expression of TrkB independently regulates myelination and progenitor cell proliferation. J Neurosci. 2013;33:4947-57 pubmed publisher
Walters R, Kraig R, Medintz I, Delehanty J, Stewart M, Susumu K, et al. Nanoparticle targeting to neurons in a rat hippocampal slice culture model. ASN Neuro. 2012;4:383-92 pubmed publisher
Candolfi M, King G, Yagiz K, Curtin J, Mineharu Y, Muhammad A, et al. Plasmacytoid dendritic cells in the tumor microenvironment: immune targets for glioma therapeutics. Neoplasia. 2012;14:757-70 pubmed
Oluich L, Stratton J, Xing Y, Ng S, Cate H, Sah P, et al. Targeted ablation of oligodendrocytes induces axonal pathology independent of overt demyelination. J Neurosci. 2012;32:8317-30 pubmed publisher
Sher F, Amor S, Gerritsen W, Baker D, Jackson S, Boddeke E, et al. Intraventricularly injected Olig2-NSCs attenuate established relapsing-remitting EAE in mice. Cell Transplant. 2012;21:1883-97 pubmed publisher
Annese V, Barcia C, Ros Bernal F, Gomez A, Ros C, De Pablos V, et al. Evidence of oligodendrogliosis in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced Parkinsonism. Neuropathol Appl Neurobiol. 2013;39:132-43 pubmed publisher
Gordon R, Mehrabi N, Maucksch C, Connor B. Chemokines influence the migration and fate of neural precursor cells from the young adult and middle-aged rat subventricular zone. Exp Neurol. 2012;233:587-94 pubmed publisher
Uchida K, Nakajima H, Watanabe S, Yayama T, Guerrero A, Inukai T, et al. Apoptosis of neurons and oligodendrocytes in the spinal cord of spinal hyperostotic mouse (twy/twy): possible pathomechanism of human cervical compressive myelopathy. Eur Spine J. 2012;21:490-7 pubmed publisher
Carpentier D, Vevis K, Trabalza A, Georgiadis C, Ellison S, Asfahani R, et al. Enhanced pseudotyping efficiency of HIV-1 lentiviral vectors by a rabies/vesicular stomatitis virus chimeric envelope glycoprotein. Gene Ther. 2012;19:761-74 pubmed publisher
Liu H, Shubayev V. Matrix metalloproteinase-9 controls proliferation of NG2+ progenitor cells immediately after spinal cord injury. Exp Neurol. 2011;231:236-46 pubmed publisher
Lepore A, O DONNELL J, Bonner J, Paul C, Miller M, Rauck B, et al. Spatial and temporal changes in promoter activity of the astrocyte glutamate transporter GLT1 following traumatic spinal cord injury. J Neurosci Res. 2011;89:1001-17 pubmed publisher
Czepiel M, Balasubramaniyan V, Schaafsma W, Stancic M, Mikkers H, Huisman C, et al. Differentiation of induced pluripotent stem cells into functional oligodendrocytes. Glia. 2011;59:882-92 pubmed publisher
Avula B, Wang Y, Ali Z, Khan I. Quantitative determination of chemical constituents from seeds of Nigella sativa L. using HPLC-UV and identification by LC-ESI-TOF. J AOAC Int. 2010;93:1778-87 pubmed
Yoshioka H, Niizuma K, Katsu M, Sakata H, Okami N, Chan P. Consistent injury to medium spiny neurons and white matter in the mouse striatum after prolonged transient global cerebral ischemia. J Neurotrauma. 2011;28:649-60 pubmed publisher
Sher F, Boddeke E, Copray S. Ezh2 expression in astrocytes induces their dedifferentiation toward neural stem cells. Cell Reprogram. 2011;13:1-6 pubmed publisher
Van Dycke A, Raedt R, Verstraete A, Theofilas P, Wadman W, Vonck K, et al. Astrocytes derived from fetal neural progenitor cells as a novel source for therapeutic adenosine delivery. Seizure. 2010;19:390-6 pubmed publisher
Robinson A, Foraker J, Ylostalo J, Prockop D. Human stem/progenitor cells from bone marrow enhance glial differentiation of rat neural stem cells: a role for transforming growth factor ? and Notch signaling. Stem Cells Dev. 2011;20:289-300 pubmed publisher
Zurita M, Otero L, Aguayo C, Bonilla C, Ferreira E, Parajón A, et al. Cell therapy for spinal cord repair: optimization of biologic scaffolds for survival and neural differentiation of human bone marrow stromal cells. Cytotherapy. 2010;12:522-37 pubmed publisher
Law S, Raisman G, Li D. Organotypic slice co-cultures reveal that early postnatal hippocampal axons lose the ability to grow along the fimbria, while retaining the ability to invade and arborise in septal neuropil. Eur J Neurosci. 2010;31:1352-8 pubmed publisher
Chang C, Lee Y, Leu S, Wang C, Wei C, Hung K, et al. CC-chemokine ligand 18/pulmonary activation-regulated chemokine expression in the CNS with special reference to traumatic brain injuries and neoplastic disorders. Neuroscience. 2010;165:1233-43 pubmed publisher
Ghulam Muhammad A, Candolfi M, King G, Yagiz K, Foulad D, Mineharu Y, et al. Antiglioma immunological memory in response to conditional cytotoxic/immune-stimulatory gene therapy: humoral and cellular immunity lead to tumor regression. Clin Cancer Res. 2009;15:6113-27 pubmed publisher
Markakis E, Sasaki M, Lankford K, Kocsis J. Convergence of cells from the progenitor fraction of adult olfactory bulb tissue to remyelinating glia in demyelinating spinal cord lesions. PLoS ONE. 2009;4:e7260 pubmed publisher
Raedt R, Van Dycke A, Waeytens A, Wyckhuys T, Vonck K, Wadman W, et al. Unconditioned adult-derived neurosphere cells mainly differentiate towards astrocytes upon transplantation in sclerotic rat hippocampus. Epilepsy Res. 2009;87:148-59 pubmed publisher
Sher F, van Dam G, Boddeke E, Copray S. Bioluminescence imaging of Olig2-neural stem cells reveals improved engraftment in a demyelination mouse model. Stem Cells. 2009;27:1582-91 pubmed publisher
Zhao J, Raha Chowdhury R, Fawcett J, Watts C. Astrocytes and oligodendrocytes can be generated from NG2+ progenitors after acute brain injury: intracellular localization of oligodendrocyte transcription factor 2 is associated with their fate choice. Eur J Neurosci. 2009;29:1853-69 pubmed publisher
Kim D, Kim J, Kwak S, Choi K, Kim D, Kwon O, et al. Spatiotemporal characteristics of astroglial death in the rat hippocampo-entorhinal complex following pilocarpine-induced status epilepticus. J Comp Neurol. 2008;511:581-98 pubmed publisher
Xiang A, Mao F, Li W, Park D, Ma B, Wang T, et al. Extensive contribution of embryonic stem cells to the development of an evolutionarily divergent host. Hum Mol Genet. 2008;17:27-37 pubmed
Raedt R, Pinxteren J, Van Dycke A, Waeytens A, Craeye D, Timmermans F, et al. Differentiation assays of bone marrow-derived Multipotent Adult Progenitor Cell (MAPC)-like cells towards neural cells cannot depend on morphology and a limited set of neural markers. Exp Neurol. 2007;203:542-54 pubmed
Vaquero J, Zurita M, Oya S, Aguayo C, Bonilla C. Early administration of methylprednisolone decreases apoptotic cell death after spinal cord injury. Histol Histopathol. 2006;21:1091-102 pubmed publisher
Zurita M, Vaquero J. Bone marrow stromal cells can achieve cure of chronic paraplegic rats: functional and morphological outcome one year after transplantation. Neurosci Lett. 2006;402:51-6 pubmed
Lin D, Wu J, Holstein D, Upadhyay G, Rourk W, Muller E, et al. Ca2+ signaling, mitochondria and sensitivity to oxidative stress in aging astrocytes. Neurobiol Aging. 2007;28:99-111 pubmed
Zurita M, Vaquero J, Oya S, Miguel M. Schwann cells induce neuronal differentiation of bone marrow stromal cells. Neuroreport. 2005;16:505-8 pubmed
Djebaili M, Guo Q, Pettus E, Hoffman S, Stein D. The neurosteroids progesterone and allopregnanolone reduce cell death, gliosis, and functional deficits after traumatic brain injury in rats. J Neurotrauma. 2005;22:106-18 pubmed
product information
Catalog Number :
MAB1580
Subcategory :
Neuroscience
Product Name :
Anti-Oligodendrocytes Antibody, clone NS-1
Product Type :
Antibodies
Clonality :
Monoclonal Antibody
Host Name :
Mouse
Antigen :
Oligodendrocytes
Clone :
NS-1
Conjugate :
Ascites
Isotype :
IgG
Product Description :
Anti-Oligodendrocytes Antibody, clone NS-1
Cross Reactivity :
Human;Hamster;Mouse;Rat
ALT Names :
RIP
Immunogen :
Rat olfactory bulb
Specificity :
Recognizes Oligodendrocytes and their myelin sheaths. MAB1580 stains both early and mature oligodendrocites.
Package Size :
100 μL
Uses :
Immunocytochemistry;Immunohistochemistry
Storage :
Maintain for 1 year at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
more info or order :
company information
EMD Millipore
290 Concord Road
Billerica, Massachusetts 01821
bioscienceshelp@emdchemical.com
https://www.emdmillipore.com
888-854-3417
headquarters: United States
EMD Millipore is the Life Science division of Merck KGaA of Darmstadt, Germany

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