| Published Application/Species/Sample/Dilution | Reference |
|---|
- western blot; mouse; 1:1000; loading ...; fig s6b
| Wegmann S, Bennett R, Delorme L, Robbins A, Hu M, McKenzie D, et al. Experimental evidence for the age dependence of tau protein spread in the brain. Sci Adv. 2019;5:eaaw6404 pubmed publisher |
- western blot; mouse; 1:1000; loading ...; fig 2b
| Saito T, Kuma A, Sugiura Y, Ichimura Y, Obata M, Kitamura H, et al. Autophagy regulates lipid metabolism through selective turnover of NCoR1. Nat Commun. 2019;10:1567 pubmed publisher |
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| Zhu C, Li B, Frontzek K, Liu Y, Aguzzi A. SARM1 deficiency up-regulates XAF1, promotes neuronal apoptosis, and accelerates prion disease. J Exp Med. 2019;216:743-756 pubmed publisher |
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| Celiku O, Tandle A, Chung J, Hewitt S, Camphausen K, Shankavaram U. Computational analysis of the mesenchymal signature landscape in gliomas. BMC Med Genomics. 2017;10:13 pubmed publisher |
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| Schatton D, Pla Martín D, Marx M, Hansen H, Mourier A, Nemazanyy I, et al. CLUH regulates mitochondrial metabolism by controlling translation and decay of target mRNAs. J Cell Biol. 2017;216:675-693 pubmed publisher |
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| Damgaard R, Walker J, Marco Casanova P, Morgan N, Titheradge H, Elliott P, et al. The Deubiquitinase OTULIN Is an Essential Negative Regulator of Inflammation and Autoimmunity. Cell. 2016;166:1215-1230.e20 pubmed publisher |
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| Hjerpe R, Bett J, Keuss M, Solovyova A, McWilliams T, Johnson C, et al. UBQLN2 Mediates Autophagy-Independent Protein Aggregate Clearance by the Proteasome. Cell. 2016;166:935-949 pubmed publisher |
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| Bosch C, Muhaisen A, Pujadas L, Soriano E, MARTINEZ A. Reelin Exerts Structural, Biochemical and Transcriptional Regulation Over Presynaptic and Postsynaptic Elements in the Adult Hippocampus. Front Cell Neurosci. 2016;10:138 pubmed publisher |
- western blot; human; fig 3
| Tagscherer K, Fassl A, Sinkovic T, Richter J, Schecher S, Macher Goeppinger S, et al. MicroRNA-210 induces apoptosis in colorectal cancer via induction of reactive oxygen. Cancer Cell Int. 2016;16:42 pubmed publisher |
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| Morisaki Y, Niikura M, Watanabe M, Onishi K, Tanabe S, Moriwaki Y, et al. Selective Expression of Osteopontin in ALS-resistant Motor Neurons is a Critical Determinant of Late Phase Neurodegeneration Mediated by Matrix Metalloproteinase-9. Sci Rep. 2016;6:27354 pubmed publisher |
- western blot; human; fig 1
| Gilson T, Blanchette P, Ballmann M, Papp T, Pénzes J, Benkő M, et al. Using the E4orf6-Based E3 Ubiquitin Ligase as a Tool To Analyze the Evolution of Adenoviruses. J Virol. 2016;90:7350-7367 pubmed publisher |
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| Kool M, van de Bree J, Bodde H, Elgersma Y, van Woerden G. The molecular, temporal and region-specific requirements of the beta isoform of Calcium/Calmodulin-dependent protein kinase type 2 (CAMK2B) in mouse locomotion. Sci Rep. 2016;6:26989 pubmed publisher |
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| Mabb A, Simon J, KING I, Lee H, An L, Philpot B, et al. Topoisomerase 1 Regulates Gene Expression in Neurons through Cleavage Complex-Dependent and -Independent Mechanisms. PLoS ONE. 2016;11:e0156439 pubmed publisher |
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| Genç B, Jara J, Schultz M, Manuel M, Stanford M, Gautam M, et al. Absence of UCHL 1 function leads to selective motor neuropathy. Ann Clin Transl Neurol. 2016;3:331-45 pubmed publisher |
- western blot; fruit fly ; 1:5000; fig 1
| Mao Y, Tamura T, Yuki Y, Abe D, Tamada Y, Imoto S, et al. The hnRNP-Htt axis regulates necrotic cell death induced by transcriptional repression through impaired RNA splicing. Cell Death Dis. 2016;7:e2207 pubmed publisher |
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| Nivon M, Fort L, Muller P, Richet E, Simon S, Guey B, et al. NF?B is a central regulator of protein quality control in response to protein aggregation stresses via autophagy modulation. Mol Biol Cell. 2016;27:1712-27 pubmed publisher |
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| Beaumatin F, El Dhaybi M, Lasserre J, Salin B, Moyer M, Verdier M, et al. N52 monodeamidated Bcl‑xL shows impaired oncogenic properties in vivo and in vitro. Oncotarget. 2016;7:17129-43 pubmed publisher |
- western blot; human; fig 1a
| Cho C, Lee K, Chen W, Wang C, Chang Y, Huang H, et al. MST3 promotes proliferation and tumorigenicity through the VAV2/Rac1 signal axis in breast cancer. Oncotarget. 2016;7:14586-604 pubmed publisher |
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| Le Pen J, Maillet L, Sarosiek K, Vuillier C, Gautier F, Montessuit S, et al. Constitutive p53 heightens mitochondrial apoptotic priming and favors cell death induction by BH3 mimetic inhibitors of BCL-xL. Cell Death Dis. 2016;7:e2083 pubmed publisher |
- western blot; mouse; 1:50,000; fig 7
- western blot; human; 1:50,000; fig 1
| Tokuda E, Brännström T, Andersen P, Marklund S. Low autophagy capacity implicated in motor system vulnerability to mutant superoxide dismutase. Acta Neuropathol Commun. 2016;4:6 pubmed publisher |
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| Allaire J, Roy S, Ouellet C, Lemieux Ã, Jones C, Paquet M, et al. Bmp signaling in colonic mesenchyme regulates stromal microenvironment and protects from polyposis initiation. Int J Cancer. 2016;138:2700-12 pubmed publisher |
- western blot; human; fig 5
| Merk H, Zhang S, Lehr T, Müller C, Ulrich M, Bibb J, et al. Inhibition of endothelial Cdk5 reduces tumor growth by promoting non-productive angiogenesis. Oncotarget. 2016;7:6088-104 pubmed publisher |
- western blot; human; fig 4
| Chen Y, Tsou B, Hu S, Ma H, Liu X, Yen Y, et al. Autophagy induction causes a synthetic lethal sensitization to ribonucleotide reductase inhibition in breast cancer cells. Oncotarget. 2016;7:1984-99 pubmed publisher |
- western blot; mouse; fig 1
| Pajoohesh Ganji A, Pal Ghosh S, Tadvalkar G, Stepp M. K14 + compound niches are present on the mouse cornea early after birth and expand after debridement wounds. Dev Dyn. 2016;245:132-43 pubmed publisher |
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| Eino A, Kageyama S, Uemura T, Annoh H, Saito T, Narita I, et al. Sqstm1-GFP knock-in mice reveal dynamic actions of Sqstm1 during autophagy and under stress conditions in living cells. J Cell Sci. 2015;128:4453-61 pubmed publisher |
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| Imai Y, Kobayashi Y, Inoshita T, Meng H, Arano T, Uemura K, et al. The Parkinson's Disease-Associated Protein Kinase LRRK2 Modulates Notch Signaling through the Endosomal Pathway. PLoS Genet. 2015;11:e1005503 pubmed publisher |
- western blot; human; fig 6f
| Selleck E, Orchard R, Lassen K, Beatty W, Xavier R, Levine B, et al. A Noncanonical Autophagy Pathway Restricts Toxoplasma gondii Growth in a Strain-Specific Manner in IFN-γ-Activated Human Cells. MBio. 2015;6:e01157-15 pubmed publisher |
- western blot; mouse; fig s8
| Fu Y, Cruz Monserrate Z, Helen Lin H, Chung Y, Ji B, Lin S, et al. Ductal activation of oncogenic KRAS alone induces sarcomatoid phenotype. Sci Rep. 2015;5:13347 pubmed publisher |
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| Nezich C, Wang C, Fogel A, Youle R. MiT/TFE transcription factors are activated during mitophagy downstream of Parkin and Atg5. J Cell Biol. 2015;210:435-50 pubmed publisher |
- immunocytochemistry; human; 1:700; fig 5
- western blot; human; 1:500; fig 1
| Maugeri G, D Amico A, Magro G, Salvatorelli L, Barbagallo G, Saccone S, et al. Expression profile of parkin isoforms in human gliomas. Int J Oncol. 2015;47:1282-92 pubmed publisher |
- immunocytochemistry; rat; 1:250; fig 1b
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| Ohnishi T, Yanazawa M, Sasahara T, Kitamura Y, Hiroaki H, Fukazawa Y, et al. Na, K-ATPase α3 is a death target of Alzheimer patient amyloid-β assembly. Proc Natl Acad Sci U S A. 2015;112:E4465-74 pubmed publisher |
- western blot; human; fig 5
| Hamazaki J, Hirayama S, Murata S. Redundant Roles of Rpn10 and Rpn13 in Recognition of Ubiquitinated Proteins and Cellular Homeostasis. PLoS Genet. 2015;11:e1005401 pubmed publisher |
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| Cho M, Park J, Choi H, Park M, Won H, Park Y, et al. DOT1L cooperates with the c-Myc-p300 complex to epigenetically derepress CDH1 transcription factors in breast cancer progression. Nat Commun. 2015;6:7821 pubmed publisher |
- western blot; human; fig 3
- western blot; mouse; fig 3
| Dombernowsky S, Samsøe Petersen J, Petersen C, Instrell R, Hedegaard A, Thomas L, et al. The sorting protein PACS-2 promotes ErbB signalling by regulating recycling of the metalloproteinase ADAM17. Nat Commun. 2015;6:7518 pubmed publisher |
| Neo S, Itahana Y, Alagu J, Kitagawa M, Guo A, Lee S, et al. TRIM28 Is an E3 Ligase for ARF-Mediated NPM1/B23 SUMOylation That Represses Centrosome Amplification. Mol Cell Biol. 2015;35:2851-63 pubmed publisher |
- immunocytochemistry; human; 1:100
| Zarkoob H, Bodduluri S, Ponnaluri S, Selby J, Sander E. Substrate Stiffness Affects Human Keratinocyte Colony Formation. Cell Mol Bioeng. 2015;8:32-50 pubmed |
- immunocytochemistry; mouse; fig 6
| Ketema M, Secades P, Kreft M, Nahidiazar L, Janssen H, Jalink K, et al. The rod domain is not essential for the function of plectin in maintaining tissue integrity. Mol Biol Cell. 2015;26:2402-17 pubmed publisher |
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| Landais I, Pelton C, Streblow D, DeFilippis V, McWeeney S, Nelson J. Human Cytomegalovirus miR-UL112-3p Targets TLR2 and Modulates the TLR2/IRAK1/NFκB Signaling Pathway. PLoS Pathog. 2015;11:e1004881 pubmed publisher |
- western blot; human; tbl s3
| Cheng H, Liang Y, Kuo Y, Chuu C, Lin C, Lee M, et al. Identification of thioridazine, an antipsychotic drug, as an antiglioblastoma and anticancer stem cell agent using public gene expression data. Cell Death Dis. 2015;6:e1753 pubmed publisher |
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| Goldstein M, Kastan M. Repair versus Checkpoint Functions of BRCA1 Are Differentially Regulated by Site of Chromatin Binding. Cancer Res. 2015;75:2699-707 pubmed publisher |
- western blot; mouse; loading ...; fig 4g
- western blot; human; loading ...; fig 3c
| Wang L, Jirka G, Rosenberg P, Buckley A, Gomez J, Fields T, et al. Gq signaling causes glomerular injury by activating TRPC6. J Clin Invest. 2015;125:1913-26 pubmed publisher |
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| Wang D, Chadha G, Feygin A, Ivanov A. F-actin binding protein, anillin, regulates integrity of intercellular junctions in human epithelial cells. Cell Mol Life Sci. 2015;72:3185-3200 pubmed publisher |
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| Xu G, Chapman J, Brandsma I, Yuan J, Mistrik M, Bouwman P, et al. REV7 counteracts DNA double-strand break resection and affects PARP inhibition. Nature. 2015;521:541-544 pubmed publisher |
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| Staudacher J, Naarmann de Vries I, Ujvari S, Klinger B, Kasim M, Benko E, et al. Hypoxia-induced gene expression results from selective mRNA partitioning to the endoplasmic reticulum. Nucleic Acids Res. 2015;43:3219-36 pubmed publisher |
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| Leirós M, Alonso E, Rateb M, Houssen W, Ebel R, Jaspars M, et al. Gracilins: Spongionella-derived promising compounds for Alzheimer disease. Neuropharmacology. 2015;93:285-93 pubmed publisher |
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| D Amico A, Maugeri G, Magro G, Salvatorelli L, Drago F, D Agata V. Expression pattern of parkin isoforms in lung adenocarcinomas. Tumour Biol. 2015;36:5133-41 pubmed publisher |
| Loganzo F, Tan X, Sung M, Jin G, Myers J, Melamud E, et al. Tumor cells chronically treated with a trastuzumab-maytansinoid antibody-drug conjugate develop varied resistance mechanisms but respond to alternate treatments. Mol Cancer Ther. 2015;14:952-63 pubmed publisher |
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| Bilal M, Zhang E, Dinkel B, Hardy D, Yankee T, Houtman J. GADS is required for TCR-mediated calcium influx and cytokine release, but not cellular adhesion, in human T cells. Cell Signal. 2015;27:841-50 pubmed publisher |
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| Naegelen I, Plançon S, Nicot N, Kaoma T, Muller A, Vallar L, et al. An essential role of syntaxin 3 protein for granule exocytosis and secretion of IL-1α, IL-1β, IL-12b, and CCL4 from differentiated HL-60 cells. J Leukoc Biol. 2015;97:557-71 pubmed publisher |
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| Choi M, Nakamura T, Cho S, Han X, Holland E, Qu J, et al. Transnitrosylation from DJ-1 to PTEN attenuates neuronal cell death in parkinson's disease models. J Neurosci. 2014;34:15123-31 pubmed publisher |
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| Ho T, Zollinger D, Chang K, Xu M, Cooper E, Stankewich M, et al. A hierarchy of ankyrin-spectrin complexes clusters sodium channels at nodes of Ranvier. Nat Neurosci. 2014;17:1664-72 pubmed publisher |
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| Chang K, Zollinger D, Susuki K, Sherman D, Makara M, Brophy P, et al. Glial ankyrins facilitate paranodal axoglial junction assembly. Nat Neurosci. 2014;17:1673-81 pubmed publisher |
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| Lin H, Lin S, Chung Y, Vonderfecht S, Camden J, Flodby P, et al. Dynamic involvement of ATG5 in cellular stress responses. Cell Death Dis. 2014;5:e1478 pubmed publisher |
| Legrand N, Araud T, Conne B, Kuijpers O, Jaquier Gubler P, Curran J. An AUG codon conserved for protein function rather than translational initiation: the story of the protein sElk1. PLoS ONE. 2014;9:e102890 pubmed publisher |
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| Chasseigneaux S, Clamagirand C, Huguet L, Gorisse Hussonnois L, Rose C, Allinquant B. Cytoplasmic SET induces tau hyperphosphorylation through a decrease of methylated phosphatase 2A. BMC Neurosci. 2014;15:82 pubmed publisher |
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| Barragán Iglesias P, Pineda Farias J, Cervantes Durán C, Bravo Hernández M, Rocha González H, Murbartián J, et al. Role of spinal P2Y6 and P2Y11 receptors in neuropathic pain in rats: possible involvement of glial cells. Mol Pain. 2014;10:29 pubmed publisher |
- flow cytometry; human; 1:10000
- immunoprecipitation; human; 1:10000
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| van de Weijer M, Bassik M, Luteijn R, Voorburg C, Lohuis M, Kremmer E, et al. A high-coverage shRNA screen identifies TMEM129 as an E3 ligase involved in ER-associated protein degradation. Nat Commun. 2014;5:3832 pubmed publisher |
| Cooper M, Koleske A. Ablation of ErbB4 from excitatory neurons leads to reduced dendritic spine density in mouse prefrontal cortex. J Comp Neurol. 2014;522:3351-62 pubmed publisher |
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| Ishikawa K, Saiki S, Furuya N, Yamada D, Imamichi Y, Li Y, et al. P150glued-associated disorders are caused by activation of intrinsic apoptotic pathway. PLoS ONE. 2014;9:e94645 pubmed publisher |
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| Chauhan H, Killinger B, Miller C, Moszczynska A. Single and binge methamphetamine administrations have different effects on the levels of dopamine D2 autoreceptor and dopamine transporter in rat striatum. Int J Mol Sci. 2014;15:5884-906 pubmed publisher |
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| van Gent M, Braem S, de Jong A, Delagic N, Peeters J, Boer I, et al. Epstein-Barr virus large tegument protein BPLF1 contributes to innate immune evasion through interference with toll-like receptor signaling. PLoS Pathog. 2014;10:e1003960 pubmed publisher |
| Machamer J, Collins S, Lloyd T. The ALS gene FUS regulates synaptic transmission at the Drosophila neuromuscular junction. Hum Mol Genet. 2014;23:3810-22 pubmed publisher |
| Praetorius C, Grill C, Stacey S, Metcalf A, Gorkin D, Robinson K, et al. A polymorphism in IRF4 affects human pigmentation through a tyrosinase-dependent MITF/TFAP2A pathway. Cell. 2013;155:1022-33 pubmed publisher |
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| Su J, Gu Y, Pruijn F, Smaill J, Patterson A, Guise C, et al. Zinc finger nuclease knock-out of NADPH:cytochrome P450 oxidoreductase (POR) in human tumor cell lines demonstrates that hypoxia-activated prodrugs differ in POR dependence. J Biol Chem. 2013;288:37138-53 pubmed publisher |
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| Milman P, Woulfe J. Novel variant of neuronal intranuclear rodlet immunoreactive for 40 kDa huntingtin associated protein and ubiquitin in the mouse brain. J Comp Neurol. 2013;521:3832-46 pubmed publisher |
| Choi J, Batchu V, Schubert M, Castellani R, Russell J. A novel PGC-1? isoform in brain localizes to mitochondria and associates with PINK1 and VDAC. Biochem Biophys Res Commun. 2013;435:671-7 pubmed publisher |
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| Will L, Portegies S, van Schelt J, van Luyk M, Jaarsma D, Hoogenraad C. Dynein activating adaptor BICD2 controls radial migration of upper-layer cortical neurons in vivo. Acta Neuropathol Commun. 2019;7:162 pubmed publisher |
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| Kenny T, Craig A, Villanueva A, Germain D. Mitohormesis Primes Tumor Invasion and Metastasis. Cell Rep. 2019;27:2292-2303.e6 pubmed publisher |
| Ramovs V, Secades P, Song J, Thijssen B, Kreft M, Sonnenberg A. Absence of integrin α3β1 promotes the progression of HER2-driven breast cancer in vivo. Breast Cancer Res. 2019;21:63 pubmed publisher |
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| Rotaru D, van Woerden G, Wallaard I, Elgersma Y. Adult Ube3a Gene Reinstatement Restores the Electrophysiological Deficits of Prefrontal Cortex Layer 5 Neurons in a Mouse Model of Angelman Syndrome. J Neurosci. 2018;38:8011-8030 pubmed publisher |
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| Chakrabarti R, Ji W, Stan R, de Juan Sanz J, Ryan T, Higgs H. INF2-mediated actin polymerization at the ER stimulates mitochondrial calcium uptake, inner membrane constriction, and division. J Cell Biol. 2018;217:251-268 pubmed publisher |
| Kirschner K, Sciesielski L, Krueger K, Scholz H. Wilms tumor protein-dependent transcription of VEGF receptor 2 and hypoxia regulate expression of the testis-promoting gene Sox9 in murine embryonic gonads. J Biol Chem. 2017;292:20281-20291 pubmed publisher |
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| Ferraiuolo R, Tubman J, Sinha I, Hamm C, Porter L. The cyclin-like protein, SPY1, regulates the ER? and ERK1/2 pathways promoting tamoxifen resistance. Oncotarget. 2017;8:23337-23352 pubmed publisher |
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| Takeda T, Yamamoto H, Kanzaki H, Suzawa K, Yoshioka T, Tomida S, et al. Yes1 signaling mediates the resistance to Trastuzumab/Lap atinib in breast cancer. PLoS ONE. 2017;12:e0171356 pubmed publisher |
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