CD11b Antibody, clone M1/70.15.1, azide free | EMD Millipore MAB1387Z product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

CD11b Antibody, clone M1/70.15.1, azide free

catalog :

MAB1387Z

quantity :

100 μg

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

M1/70.15.1

reactivity :

human, mouse

application :

immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - frozen section, blocking or activating experiments

citations: 14

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry; mouse; 1:2000; loading ...; fig 5e	Wendeln A, Degenhardt K, Kaurani L, Gertig M, Ulas T, Jain G, et al. Innate immune memory in the brain shapes neurological disease hallmarks. Nature. 2018;556:332-338 pubmed publisher
blocking or activating experiments; human; loading ...; fig 1e	Li L, Qi X, Sun W, Abdel Azim H, Lou S, Zhu H, et al. Am80-GCSF synergizes myeloid expansion and differentiation to generate functional neutrophils that reduce neutropenia-associated infection andÂ mortality. EMBO Mol Med. 2016;8:1340-1359 pubmed publisher
immunohistochemistry; mouse; 1:500; loading ...	Morrison H, Filosa J. Sex differences in astrocyte and microglia responses immediately following middle cerebral artery occlusion in adult mice. Neuroscience. 2016;339:85-99 pubmed publisher
immunohistochemistry - frozen section; mouse; 1:200; loading ...; fig 7k	Lizen B, Hutlet B, Bissen D, Sauvegarde D, Hermant M, Ahn M, et al. HOXA5 localization in postnatal and adult mouse brain is suggestive of regulatory roles in postmitotic neurons. J Comp Neurol. 2017;525:1155-1175 pubmed publisher
immunocytochemistry; mouse	Bhaskar K, Maphis N, Xu G, Varvel N, Kokiko Cochran O, Weick J, et al. Microglial derived tumor necrosis factor-? drives Alzheimer's disease-related neuronal cell cycle events. Neurobiol Dis. 2014;62:273-85 pubmed publisher
immunohistochemistry; mouse; 1:200	Goemaere J, Knoops B. Peroxiredoxin distribution in the mouse brain with emphasis on neuronal populations affected in neurodegenerative disorders. J Comp Neurol. 2012;520:258-80 pubmed publisher
	Bernal Chico A, Canedo M, Manterola A, Victoria Sánchez Gómez M, Perez Samartin A, Rodriguez Puertas R, et al. Blockade of monoacylglycerol lipase inhibits oligodendrocyte excitotoxicity and prevents demyelination in vivo. Glia. 2015;63:163-76 pubmed publisher
	Tanaka Y, Chambers J, Matsuwaki T, Yamanouchi K, Nishihara M. Possible involvement of lysosomal dysfunction in pathological changes of the brain in aged progranulin-deficient mice. Acta Neuropathol Commun. 2014;2:78 pubmed publisher
	Nagano J, Shimizu M, Hara T, Shirakami Y, Kochi T, Nakamura N, et al. Effects of indoleamine 2,3-dioxygenase deficiency on high-fat diet-induced hepatic inflammation. PLoS ONE. 2013;8:e73404 pubmed publisher
	Ji K, Akgul G, Wollmuth L, Tsirka S. Microglia actively regulate the number of functional synapses. PLoS ONE. 2013;8:e56293 pubmed publisher
	Morrison H, Filosa J. A quantitative spatiotemporal analysis of microglia morphology during ischemic stroke and reperfusion. J Neuroinflammation. 2013;10:4 pubmed publisher
	Wei H, Teng H, Huan W, Zhang S, Fu H, Chen F, et al. An upregulation of SENP3 after spinal cord injury: implications for neuronal apoptosis. Neurochem Res. 2012;37:2758-66 pubmed publisher
	Wang D, Lu Q, Shao B, Cui G, Wang Y, Liu Y, et al. An upregulation of SIAH1 after spinal cord injury in adult rats. J Mol Neurosci. 2011;45:134-44 pubmed publisher
	Zaheer A, Zaheer S, Sahu S, Knight S, Khosravi H, Mathur S, et al. A novel role of glia maturation factor: induction of granulocyte-macrophage colony-stimulating factor and pro-inflammatory cytokines. J Neurochem. 2007;101:364-76 pubmed

product information

Catalog Number :

MAB1387Z

Subcategory :

Cell Structure

Product Name :

Anti-CD11b Antibody, clone M1/70.15.1, azide free

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P11215

Host Name :

Rat

Antigen :

CD11b

Clone :

M1/70.15.1

Conjugate :

Purified

Isotype :

IgG2b

Product Description :

Anti-CD11b Antibody, clone M1/70.15.1, azide free

Cross Reactivity :

Human;Mouse

ALT Names :

IntegrinalphaM;Mac-1a;MAB1387

Immunogen :

T cell enriched splenocytes from B10 mice

Specificity :

Recognizes the murine alphaM integrin chain, which exists as a heterodimer with the beta2 integrin (Springer, 1979; Springer, 1990). The antibody stains polymorphonuclear cells, monocytes and NK cells. Variable activity is reported with tissue macrophages. M1/70.15.1 blocks iC3b binding to its receptor (Beller, 1982).

Package Size :

100 μg

Uses :

Flow Cytometry;Immunofluorescence;Immunohistochemistry;Immunoprecipitation;Affects Function

Storage :

Maintain for 2 years at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.