Integrin α6B Antibody, cytoplasmic domain, clone 6B4 | EMD Millipore MAB1358 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Integrin α6B Antibody, cytoplasmic domain, clone 6B4

catalog :

MAB1358

quantity :

100 µg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

6B4

The same clone is also sold as:

LifeSpan Biosciences: LS-C146761
OriGene: BM6027P
Santa Cruz Biotechnology: sc-59971

reactivity :

human, mouse

application :

western blot, immunohistochemistry, immunocytochemistry

citations: 1

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry; mouse	Barbaro V, Ferrari S, Fasolo A, Ponzin D, Di Iorio E. Reconstruction of a human hemicornea through natural scaffolds compatible with the growth of corneal epithelial stem cells and stromal keratocytes. Mol Vis. 2009;15:2084-93 pubmed

product information

Catalog Number :

MAB1358

Subcategory :

Cell Structure

Product Name :

Anti-Integrin α6B Antibody, cytoplasmic domain, clone 6B4

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P23229

Host Name :

Mouse

Antigen :

Integrin α6B

Clone :

6B4

Conjugate :

Purified

Isotype :

IgG1

Product Description :

Anti-Integrin α6B Antibody, cytoplasmic domain, clone 6B4

Cross Reactivity :

Human

Background :

Integrins are a family of heterodimeric membrane glycoproteins consisting of non-covalently associated alpha and beta subunits. More than 18 alpha and 8 beta subunits with numerous splice variant isoforms have been identified in mammals. In general, integrin function as receptors for extracellular matrix proteins. Certain integrins can also bind to soluble ligands or to counter-receptors on adjacent cells, such as the intracellular adhesion molecules (ICAMs), resulting in aggregation of cells. Signals transduced by integrins play a role in many biological processes, including cell growth, differentiation, migration and apoptosis. For integrin subunits alpha 3 and alpha6, two cytoplasmic variants, A and B, have been identified.

ALT Names :

CD49f

Immunogen :

Synthetic Peptide to the cytoplasmic domain of integrin subunit alpha6B including an appending N-terminal cysteine: CSRYDDSVPRYHAVRIRKEEREIKDEKYIDNLEKK

Specificity :

MAB1358 recognizes specifically the cytoplasmic domain of integrin subunit alpha 6B. The antibody stains the basement membrane zone of ducts and acini of salivary gland, kidney tubules, epithelium of colonic crypts and weakly stains sweat glands and sebaceous glands. Broad species reactivity is expected due to the conserved nature of the epitope.

Package Size :

100 µg

Uses :

Western Blotting;Immunocytochemistry;Immunohistochemistry

Storage :

Store at 2-8°C, or -20°C in small aliquots for up to 12 months after date of receipt. Avoid freeze/thaw cycles.