Cav1.2 calcium channel Antibody, clone L57/46 | EMD Millipore MAB13170 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Cav1.2 calcium channel Antibody, clone L57/46

catalog :

MAB13170

quantity :

100 μg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

L57/46

The same clone is also sold as:

OriGene: 73-053, 75-053
Neuromab: 73-053, 75-053

reactivity :

domestic rabbit

application :

western blot, immunohistochemistry

citations: 2

Reference
Furusawa K, Asada A, Saito T, Hisanaga S. The effect of Cyclin-dependent kinase 5 on voltage-dependent calcium channels in PC12 cells varies according to channel type and cell differentiation state. J Neurochem. 2014;130:498-506 pubmed publisher
Zorrilla de San Martín J, Pyott S, Ballestero J, Katz E. Ca(2+) and Ca(2+)-activated K(+) channels that support and modulate transmitter release at the olivocochlear efferent-inner hair cell synapse. J Neurosci. 2010;30:12157-67 pubmed publisher

product information

Catalog Number :

MAB13170

Subcategory :

Neuroscience

Product Name :

Anti-Cav1.2 calcium channel Antibody, clone L57/46

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P15381

Host Name :

Mouse

Antigen :

Cav1.2 calcium channel

Clone :

L57/46

Conjugate :

Purified

Isotype :

IgG2bκ

Product Description :

Anti-Cav1.2 calcium channel Antibody, clone L57/46

Cross Reactivity :

Mouse;Human;Rat;Rabbit

Background :

This gene encodes an alpha-1 subunit of a voltage-dependent calcium channel. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization. The alpha-1 subunit consists of 24 transmembrane segments and forms the pore through which ions pass into the cell. The calcium channel consists of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. There are multiple isoforms of each of these proteins, either encoded by different genes or the result of alternative splicing of transcripts. The protein encoded by this gene binds to and is inhibited by dihydropyridine. Many alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.

ALT Names :

calcium channel, voltage-dependent, L type, alpha 1C subunit1;voltage-gated calcium channel alpha subunit Cav1.2;calcium channel, L type, alpha 1 polypeptide, isoform 1, cardic muscle;calcium channel, cardic dihydropyridine-sensitive, alpha-1 subunit;voltage-gated L-type calcium channel Cav1.2 alpha 1 subunit, splice variant 10*;DHPR, alpha-1 subunit;Voltage-gated calcium channel subunit alpha Cav1.2;Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle

Immunogen :

Recombinant protein corresponding to rabbit Cav1.2 calcium channel at the cytoplasmic domain proximal to the C-terminus.

Specificity :

This antibody recognizes Cav1.2 calcium channel at the cytoplasmic domain.

Package Size :

100 μg

Uses :

Western Blotting;Immunohistochemistry

Storage :

Stable for 1 year at 2-8°C from date of receipt