This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
EMD Millipore
other brands :
Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava
product type :
antibody
product name :
DNA Antibody, double stranded, clone AE-2
catalog :
MAB1293
quantity :
100 µg
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
AE-2
reactivity :
Singapore grouper iridovirus, human, mouse
application :
immunohistochemistry, immunocytochemistry, chromatin immunoprecipitation
citations: 8
Published Application/Species/Sample/DilutionReference
  • immunocytochemistry; mouse; 1:200; loading ...; fig s2e
Amini P, Stojkov D, Felser A, Jackson C, Courage C, Schaller A, et al. Neutrophil extracellular trap formation requires OPA1-dependent glycolytic ATP production. Nat Commun. 2018;9:2958 pubmed publisher
  • chromatin immunoprecipitation; human; fig 5
Starokadomskyy P, Gemelli T, Rios J, Xing C, Wang R, Li H, et al. DNA polymerase-? regulates the activation of type I interferons through cytosolic RNA:DNA synthesis. Nat Immunol. 2016;17:495-504 pubmed publisher
  • immunocytochemistry; Singapore grouper iridovirus; fig 3
Liu Y, Tran B, Wang F, Ounjai P, Wu J, Hew C. Visualization of Assembly Intermediates and Budding Vacuoles of Singapore Grouper Iridovirus in Grouper Embryonic Cells. Sci Rep. 2016;6:18696 pubmed publisher
Wang J, Ba G, Han Y, Ming S, Wang M, Fu P, et al. Cyclic GMP-AMP synthase is essential for cytosolic double-stranded DNA and fowl adenovirus serotype 4 triggered innate immune responses in chickens. Int J Biol Macromol. 2020;146:497-507 pubmed publisher
Puttaraksa K, Pirttinen H, Karvonen K, Nykky J, Naides S, Gilbert L. Parvovirus B19V Nonstructural Protein NS1 Induces Double-Stranded Deoxyribonucleic Acid Autoantibodies and End-Organ Damage in Nonautoimmune Mice. J Infect Dis. 2019;219:1418-1429 pubmed publisher
Li H, Yao Q, Mariscal A, Wu X, Hulse J, Pedersen E, et al. Epigenetic control of IL-23 expression in keratinocytes is important for chronic skin inflammation. Nat Commun. 2018;9:1420 pubmed publisher
Johnson G, Swart C, Moore S. Interaction of acetylcholinesterase with the G4 domain of the laminin alpha1-chain. Biochem J. 2008;411:507-14 pubmed publisher
Nakamura T, Arai Y, Umehara H, Masuhara M, Kimura T, Taniguchi H, et al. PGC7/Stella protects against DNA demethylation in early embryogenesis. Nat Cell Biol. 2007;9:64-71 pubmed
product information
Catalog Number :
MAB1293
Subcategory :
Epigenetics & Nuclear Function
Product Name :
Anti-DNA Antibody, double stranded, clone AE-2
Product Type :
Antibodies
Clonality :
Monoclonal Antibody
Host Name :
Mouse
Antigen :
DNA
Clone :
AE-2
Conjugate :
Purified
Isotype :
IgG3
Product Description :
Anti-DNA Antibody, double stranded, clone AE-2
Cross Reactivity :
All
Immunogen :
Nuclei of Raji Burkitt's lymphoma cells
Specificity :
Double stranded DNA. MAB1293 produces a homogeneous staining pattern in the nucleus of normal and malignant cells.
Package Size :
100 µg
Uses :
Immunocytochemistry;Immunohistochemistry
Storage :
Maintain at 2-8°C in undiluted aliquots for up to 6 months.
company information
EMD Millipore
290 Concord Road
Billerica, Massachusetts 01821
bioscienceshelp@emdchemical.com
https://www.emdmillipore.com
888-854-3417
headquarters: United States
EMD Millipore is the Life Science division of Merck KGaA of Darmstadt, Germany

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