Chymase Antibody, clone B7, biotin conjugated | EMD Millipore MAB1254B product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Chymase Antibody, clone B7, biotin conjugated

catalog :

MAB1254B

quantity :

100 µg

clonality :

monoclonal

host :

mouse

conjugate :

biotin

clone name :

B7

The same clone is also sold as:

LifeSpan Biosciences: LS-C25448

reactivity :

human

application :

immunohistochemistry, flow cytometry

citations: 3

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human; fig 3	Kirshenbaum A, Cruse G, Desai A, Bandara G, Leerkes M, Lee C, et al. Immunophenotypic and Ultrastructural Analysis of Mast Cells in Hermansky-Pudlak Syndrome Type-1: A Possible Connection to Pulmonary Fibrosis. PLoS ONE. 2016;11:e0159177 pubmed publisher
	Suekane T, Ikura Y, Watanabe K, Arimoto J, Iwasa Y, Sugama Y, et al. Phenotypic change and accumulation of smooth muscle cells in strictures in Crohn's disease: relevance to local angiotensin II system. J Gastroenterol. 2010;45:821-30 pubmed publisher
	Fukushima H, Ohsawa M, Ikura Y, Naruko T, Sugama Y, Suekane T, et al. Mast cells in diffuse large B-cell lymphoma; their role in fibrosis. Histopathology. 2006;49:498-505 pubmed

product information

Catalog Number :

MAB1254B

Subcategory :

Inflammation & Immunology

Product Name :

Anti-Chymase Antibody, clone B7, biotin conjugated

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P23946

Host Name :

Mouse

Antigen :

Chymase

Clone :

Conjugate :

Biotin

Isotype :

IgG1κ

Product Description :

Anti-Chymase Antibody, clone B7, biotin conjugated

Cross Reactivity :

Human

Background :

Mast cell chymase (EC 3.4.21.39), a member of the granzyme subfamily of the S1 family of peptidases, cleaves C-terminal to Phenylalanine, Tyrosine, Tryptophan, and Leucine residues (in order of preference). Chymase is stored in Mast cell granules within the cell and is the major secreated Mast cell protease. Secreated Mast cell chymase is believed to be involved in extracellular matrix degradation, vasoactive peptide generation, and regulation of gland secreation.

ALT Names :

Mast Cell Protease I

Immunogen :

Chymase purified from human skin.

Specificity :

Reacts with human mast cell chymase.

Package Size :

100 µg

Uses :

Dot Blot;Immunohistochemistry

Storage :

Maintain at 2-8°C in undiluted aliquots for up to 12 months from date of receipt.