Chymase Antibody, clone B7 | EMD Millipore MAB1254 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Chymase Antibody, clone B7

catalog :

MAB1254

quantity :

100 µg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

B7

The same clone is also sold as:

LifeSpan Biosciences: LS-C25448

reactivity :

human

application :

immunohistochemistry

citations: 6

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry; human	Fujisawa D, Kashiwakura J, Kita H, Kikukawa Y, Fujitani Y, Sasaki Sakamoto T, et al. Expression of Mas-related gene X2 on mast cells is upregulated in the skin of patients with severe chronic urticaria. J Allergy Clin Immunol. 2014;134:622-633.e9 pubmed publisher
	Hofman V, Lassalle S, Selva E, Kalem K, Steff A, Hebuterne X, et al. Involvement of mast cells in gastritis caused by Helicobacter pylori: a potential role in epithelial cell apoptosis. J Clin Pathol. 2007;60:600-7 pubmed
	Hirata K, Sugama Y, Ikura Y, Ohsawa M, Inoue Y, Yamamoto S, et al. Enhanced mast cell chymase expression in human idiopathic interstitial pneumonia. Int J Mol Med. 2007;19:565-70 pubmed
	Jayapal M, Tay H, Reghunathan R, Zhi L, Chow K, Rauff M, et al. Genome-wide gene expression profiling of human mast cells stimulated by IgE or FcepsilonRI-aggregation reveals a complex network of genes involved in inflammatory responses. BMC Genomics. 2006;7:210 pubmed
	Wang X, Yip K, Sam S, Lau H. Buffy coat preparation is a convenient source of progenitors for culturing mature human mast cells. J Immunol Methods. 2006;309:69-74 pubmed
	Kaur D, Berger P, Duffy S, Brightling C, Bradding P. Co-cultivation of mast cells and Fc epsilon RI alpha+ dendritic-like cells from human hip bone marrow. Clin Exp Allergy. 2005;35:226-33 pubmed

product information

Catalog Number :

MAB1254

Subcategory :

Inflammation & Immunology

Product Name :

Anti-Chymase Antibody, clone B7

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P23946

Host Name :

Mouse

Antigen :

Chymase

Clone :

Conjugate :

Purified

Isotype :

IgG1κ

Product Description :

Anti-Chymase Antibody, clone B7

Cross Reactivity :

Human

Background :

Mast cell chymase (EC 3.4.21.39), a member of the granzyme subfamily of the S1 family of peptidases, cleaves C-terminal to Phenylalanine, Tyrosine, Tryptophan, and Leucine residues (in order of preference). Chymase is stored in Mast cell granules within the cell and is the major secreated Mast cell protease. Secreated Mast cell chymase is believed to be involved in extracellular matrix degradation, vasoactive peptide generation, and regulation of gland secreation.

ALT Names :

Mast Cell Protease I

Immunogen :

Chymase purified from human skin.

Specificity :

Reacts with human mast cell chymase.

Package Size :

100 µg

Uses :

Dot Blot;Immunohistochemistry

Storage :

Maintain at 2-8°C in undiluted aliquots for up to 12 months from date of receipt. Antibody may also be stored at -20 C in undiluted aliquots.