Interferon-α/β Receptor Chain 2 Antibody, clone MMHAR-2 | EMD Millipore MAB1155 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Interferon-α/β Receptor Chain 2 Antibody, clone MMHAR-2

catalog :

MAB1155

quantity :

50 µg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

MMHAR-2

reactivity :

human

application :

immunohistochemistry, immunoprecipitation, flow cytometry, blocking or activating experiments

citations: 12

Published Application/Species/Sample/Dilution	Reference
blocking or activating experiments; human; 1:100; loading ...; fig 3c	Pautasso S, Galitska G, Dell Oste V, Biolatti M, Cagliani R, Forni D, et al. Strategy of Human Cytomegalovirus To Escape Interferon Beta-Induced APOBEC3G Editing Activity. J Virol. 2018;92: pubmed publisher
blocking or activating experiments; human; loading ...; fig 5a	Decalf J, Desdouits M, Rodrigues V, Gobert F, Gentili M, Marques Ladeira S, et al. Sensing of HIV-1 Entry Triggers a Type I Interferon Response in Human Primary Macrophages. J Virol. 2017;91: pubmed publisher
blocking or activating experiments; human	Buitendijk M, Eszterhas S, Howell A. Gardiquimod: a Toll-like receptor-7 agonist that inhibits HIV type 1 infection of human macrophages and activated T cells. AIDS Res Hum Retroviruses. 2013;29:907-18 pubmed publisher
	Merindol N, El Far M, Sylla M, Masroori N, Dufour C, Li J, et al. HIV-1 capsids from B27/B57+ elite controllers escape Mx2 but are targeted by TRIM5α, leading to the induction of an antiviral state. PLoS Pathog. 2018;14:e1007398 pubmed publisher
	Yurchenko M, Skjesol A, Ryan L, Richard G, Kandasamy R, Wang N, et al. SLAMF1 is required for TLR4-mediated TRAM-TRIF-dependent signaling in human macrophages. J Cell Biol. 2018;217:1411-1429 pubmed publisher
	Esteso G, Guerra S, Vales Gomez M, Reyburn H. Innate immune recognition of double-stranded RNA triggers increased expression of NKG2D ligands after virus infection. J Biol Chem. 2017;292:20472-20480 pubmed publisher
	Cerboni S, Jeremiah N, Gentili M, Gehrmann U, Conrad C, Stolzenberg M, et al. Intrinsic antiproliferative activity of the innate sensor STING in T lymphocytes. J Exp Med. 2017;214:1769-1785 pubmed publisher
	Ogony J, Choi H, Lui A, Cristofanilli M, Lewis Wambi J. Interferon-induced transmembrane protein 1 (IFITM1) overexpression enhances the aggressive phenotype of SUM149 inflammatory breast cancer cells in a signal transducer and activator of transcription 2 (STAT2)-dependent manner. Breast Cancer Res. 2016;18:25 pubmed publisher
	Kim Y, Ahn J. Positive role of promyelocytic leukemia protein in type I interferon response and its regulation by human cytomegalovirus. PLoS Pathog. 2015;11:e1004785 pubmed publisher
	Choi H, Lui A, Ogony J, Jan R, Sims P, Lewis Wambi J. Targeting interferon response genes sensitizes aromatase inhibitor resistant breast cancer cells to estrogen-induced cell death. Breast Cancer Res. 2015;17:6 pubmed publisher
	Kägebein D, Gutjahr M, Große C, Vogel A, Rödel J, Knittler M. Chlamydia trachomatis-infected epithelial cells and fibroblasts retain the ability to express surface-presented major histocompatibility complex class I molecules. Infect Immun. 2014;82:993-1006 pubmed publisher
	Zhang T, Lin R, Li Y, Douglas S, Maxcey C, Ho C, et al. Hepatitis C virus inhibits intracellular interferon alpha expression in human hepatic cell lines. Hepatology. 2005;42:819-27 pubmed

product information

Catalog Number :

MAB1155

Subcategory :

Inflammation & Immunology

Product Name :

Anti-Interferon-α/β Receptor Chain 2 Antibody, clone MMHAR-2

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P01563

Host Name :

Mouse

Antigen :

Interferon-α/β Receptor Chain 2

Clone :

MMHAR-2

Conjugate :

Purified

Isotype :

IgG2a

Product Description :

Anti-Interferon-α/β Receptor Chain 2 Antibody, clone MMHAR-2

Cross Reactivity :

Human

ALT Names :

CD118

Immunogen :

Human Interferon alpha/beta Receptor Chain 2

Specificity :

Reacts with Human Interferon alpha/beta Receptor Chain 2 (CD118). Antibody neutralizes human interferon alpha receptor, interacts with extracellular domain, binds to human interferon alpha receptor with high affinity, and blocks biological action of Type I interferons.

Package Size :

50 µg

Uses :

Flow Cytometry;Immunoprecipitation;Immunohistochemistry;Affects Function

Storage :

Maintain frozen at -20°C or below for retention of full activity, for up to 12 months. When thawing, the contents of the tube should be apportioned in separate tubes so that freezing and thawing is kept to a minimum.