hnRNP Q Antibody, clone 7A11.2 | EMD Millipore MAB11004 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

hnRNP Q Antibody, clone 7A11.2

catalog :

MAB11004

quantity :

100 μg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

7A11.2

reactivity :

human, mouse

application :

western blot, immunocytochemistry, immunoprecipitation

citations: 1

Published Application/Species/Sample/Dilution	Reference
immunoprecipitation; human; loading ...; fig 6a western blot; human; loading ...; fig 4b	Vu L, Prieto C, Amin E, Chhangawala S, Krivtsov A, Calvo Vidal M, et al. Functional screen of MSI2 interactors identifies an essential role for SYNCRIP in myeloid leukemia stem cells. Nat Genet. 2017;49:866-875 pubmed publisher

product information

Catalog Number :

MAB11004

Subcategory :

Epigenetics & Nuclear Function

Product Name :

Anti-hnRNP Q Antibody, clone 7A11.2

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

O60506

Host Name :

Mouse

Antigen :

hnRNP Q

Clone :

7A11.2

Conjugate :

Purified

Isotype :

IgG1κ

Product Description :

Anti-hnRNP Q Antibody, clone 7A11.2

Cross Reactivity :

Human;Mouse;Rat

Background :

Heterogeneous nuclear ribonucleoprotein Q, commonly refered to as hnRNP Q, can be found as three different isoforms derived from alternative splicing of a single gene. This RNA binding protein is implicated in control of mRNA precursor splicing for the survival of motor neurons (SMN) protein. Loss-of-function mutations of SMN are linked to spinal muscular atrophy (SMA) a common neurodegenerative disease. It has been shown that hnRNP Q proteins interact with SMN, and this is interacton is required for efficient pre-mRNA splicing in vitro. Current data suggests that hnRNP Q is a splicing modulator of SMN.

ALT Names :

heterogeneous nuclear ribonucleoprotein Q-like;Synaptotagmin-binding, cytoplasmic RNA-interacting protein;Glycine- and tyrosine-rich RNA-binding protein;GRY-RBP;NS1-associated protein 1

Immunogen :

Full length recombinant protein corresponding to human hnRNPQ.

Package Size :

100 μg

Uses :

Western Blotting;Immunocytochemistry

Storage :

Stable for 1 year at 2-8°C from date of receipt