Transthyretin Antibody, clone 7G8-E11-E7 | EMD Millipore MAB10762 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Transthyretin Antibody, clone 7G8-E11-E7

catalog :

MAB10762

quantity :

100 μg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

7G8-E11-E7

reactivity :

human

application :

western blot, ELISA

product information

Catalog Number :

MAB10762

Subcategory :

Neuroscience

Product Name :

Anti-Transthyretin Antibody, clone 7G8-E11-E7

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P02766

Host Name :

Mouse

Antigen :

Transthyretin

Clone :

7G8-E11-E7

Conjugate :

Purified

Isotype :

IgG2aκ

Product Description :

Anti-Transthyretin Antibody, clone 7G8-E11-E7

Cross Reactivity :

Human

Background :

Transthyretin is one of the three major thyroid hormone-binding proteins in plasma and/or cerebrospinal fluid of vertebrates. It exists mainly as a homotetrameric protein of approximately 55 kDa in plasma and, in sera and cerebrospinal fluid, is a carrier of the thyroid hormone thyroxine (T4) and retinol. While mostly known for being the transporter of thyroxine and retinol, when mutated, TTR is also well-described as the cause of familial amyloid polyneuropathy, a neurodegenerative lethal disorder characterized by systemic deposition of TTR amyloid fibrils, particularly in the peripheral nervous system. Recently, studies have shown that TTR has an important function development of peripheral and central nervous system physiology, namely by participating in behavior, in the maintenance of normal cognitive processes during ageing, amidated neuropeptide processing and nerve regeneration. Additionally, it has been proposed that TTR is neuroprotective in Alzheimer's disease, by preventing the formation of amyloid beta fibrils (Fleming C.E. et al. (2009) Prog Neurobiol., Epub ahead of print

ALT Names :

prealbumin, amyloidosis type I;thyroxine-binding prealbumin;TBPA;TTR;ATTR

Immunogen :

Purified human Transthyretin.

Specificity :

This antibody recognizes Transthyretin.

Package Size :

100 μg

Uses :

ELISA;Western Blotting

Storage :

Stable for 1 year at 2-8°C from date of receipt