Plexin-A1 Antibody, clone 14A1.2 | EMD Millipore MAB10419 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Plexin-A1 Antibody, clone 14A1.2

catalog :

MAB10419

quantity :

100 μg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

14A1.2

reactivity :

human

application :

western blot

product information

Catalog Number :

MAB10419

Subcategory :

Neuroscience

Product Name :

Anti-Plexin-A1 Antibody, clone 14A1.2

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

Q9UIW2

Host Name :

Mouse

Antigen :

Plexin-A1

Clone :

14A1.2

Conjugate :

Purified

Isotype :

IgG1κ

Product Description :

Anti-Plexin-A1 Antibody, clone 14A1.2

Cross Reactivity :

Human

Background :

Although Plexin-A1 is a semaphorin receptor that is most commonly expressed in dendritic cells, it is most recognized as a proprioceptive sensory axon-specific receptor for Semaphorin-6C and Semaphorin-6D. Its most prominent role for sema6C/6D-plexinA1 signaling in sensory neuron development appears to be in the control of proprioceptive axon shaft position. In the absence of Plexin-A1 a breakdown of the exclusion of proprioceptive axon shafts from the superficial dorsal horn is observed, but without an impact on axon collateral trajectory. Plexin-A1 appears to be involved in T cell activation and may play a role in angiogenesis. A potential marker for dendritic cell maturity, Plexin-A1 has been found in the cytoplasm of the immature dendritic cells while localizing to the membranes of the mature ones.

ALT Names :

Plexin-A1;Semaphorin receptor NOV

Immunogen :

GST-tagged recombinant protein corresponding to human Plexin-A1.

Package Size :

100 μg

Uses :

Western Blotting

Storage :

Stable for 1 year at 2-8°C from date of receipt