IDO Antibody, clone 1F8.2 | EMD Millipore MAB10009 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

IDO Antibody, clone 1F8.2

catalog :

MAB10009

quantity :

100 μg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

1F8.2

reactivity :

human

application :

western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section

citations: 8

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry - paraffin section; human; 4 ug/ml; loading ...; fig 1 western blot; human; 1 ug/ml; loading ...	Carvajal Hausdorf D, Mani N, Velcheti V, Schalper K, Rimm D. Objective measurement and clinical significance of IDO1 protein in hormone receptor-positive breast cancer. J Immunother Cancer. 2017;5:81 pubmed publisher
western blot; human; fig s7	Adhikary T, Wortmann A, Schumann T, Finkernagel F, Lieber S, Roth K, et al. The transcriptional PPARÎ²/Î´ network in human macrophages defines a unique agonist-induced activation state. Nucleic Acids Res. 2015;43:5033-51 pubmed publisher
immunohistochemistry - paraffin section; human; 1:50 immunocytochemistry; human; 1:50	Vorobjova T, Uibo O, Heilman K, Uibo R. Increased density of tolerogenic dendritic cells in the small bowel mucosa of celiac patients. World J Gastroenterol. 2015;21:439-52 pubmed publisher
	Grozdics E, Berta L, Gyarmati B, Veres G, Zadori D, Szalárdy L, et al. B7 costimulation and intracellular indoleamine 2,3-dioxygenase expression in umbilical cord blood and adult peripheral blood. Biol Blood Marrow Transplant. 2014;20:1659-65 pubmed publisher
	Park G, Choi Y, Lee S, Lim J, Lee C, Choi E, et al. A paradoxical pattern of indoleamine 2,3-dioxygenase expression in the colon tissues of patients with acute graft-versus-host disease. Exp Hematol. 2014;42:734-40 pubmed publisher
	Moretti S, Menicali E, Voce P, Morelli S, Cantarelli S, Sponziello M, et al. Indoleamine 2,3-dioxygenase 1 (IDO1) is up-regulated in thyroid carcinoma and drives the development of an immunosuppressant tumor microenvironment. J Clin Endocrinol Metab. 2014;99:E832-40 pubmed publisher
	Iversen T, Engell Noerregaard L, Ellebaek E, Andersen R, Larsen S, Bjoern J, et al. Long-lasting disease stabilization in the absence of toxicity in metastatic lung cancer patients vaccinated with an epitope derived from indoleamine 2,3 dioxygenase. Clin Cancer Res. 2014;20:221-32 pubmed publisher
	Vasania V, Prasad P, Gill R, Mehta A, Viswanathan C, Sarang S, et al. Molecular and cellular characterization of expanded and cryopreserved human limbal epithelial stem cells reveal unique immunological properties. Exp Eye Res. 2011;92:47-56 pubmed publisher

product information

Catalog Number :

MAB10009

Subcategory :

Neuroscience

Product Name :

Anti-IDO Antibody, clone 1F8.2

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P14902

Host Name :

Mouse

Antigen :

IDO

Clone :

1F8.2

Conjugate :

Purified

Isotype :

IgG1κ

Product Description :

Anti-IDO Antibody, clone 1F8.2

Cross Reactivity :

Human

Background :

Indoleamine 2,3-dioxygenase (IDO) is an enzyme that is responsible for converting tryptophan to kynurenines. IDO is expressed by a wide variety of tissues and IDO can be upregulated by interferon gamma. IDO modulates levels of the amino acid tryptophan, which is vital for cell growth, but is also involved in the suppression of the immune response. IDO may be involved in the suppression of the immune response to tumours and blocking the IDO pathway may be a potential target for immunotherapy.

ALT Names :

Indoleamine-pyrrole 2,3-dioxygenase ;indole 2,3-dioxygenase ;indoleamine 2,3-dioxygenase 1 ;indoleamine-pyrrole 2,3 dioxygenase

Immunogen :

GST-tagged recombinant protein of full-length human IDO.

Specificity :

This antibody recognizes IDO.

Package Size :

100 μg

Uses :

Western Blotting;Immunohistochemistry

Storage :

Maintain refrigerated at 2-8°C for 1 year from date of receipt.