S-100 Protein Antibody, clone 15E2E2 | EMD Millipore MAB079-1 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

S-100 Protein Antibody, clone 15E2E2

catalog :

MAB079-1

quantity :

100 µL

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

15E2E2

The same clone is also sold as:

Biogenex: MU058-5UC

reactivity :

guinea pig, human, mouse, rat

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

citations: 26

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry - paraffin section; rat; 1:1000; loading ...; fig 3a	Mammone T, Chidlow G, Casson R, Wood J. Improved immunohistochemical detection of phosphorylated mitogen-activated protein kinases in the injured rat optic nerve head. Histochem Cell Biol. 2019;151:435-456 pubmed publisher
immunohistochemistry - paraffin section; human; loading ...; fig s7b	Pratt D, Dominah G, Lobel G, Obungu A, Lynes J, Sanchez V, et al. Programmed Death Ligand 1 Is a Negative Prognostic Marker in Recurrent Isocitrate Dehydrogenase-Wildtype Glioblastoma. Neurosurgery. 2018;: pubmed publisher
immunohistochemistry - paraffin section; mouse; 1:200; loading ...; fig 6d	Kemp K, Cerminara N, Hares K, Redondo J, Cook A, Haynes H, et al. Cytokine therapy-mediated neuroprotection in a Friedreich's ataxia mouse model. Ann Neurol. 2017;81:212-226 pubmed publisher
immunohistochemistry - frozen section; human; 1:250; fig 1	Deborde S, Omelchenko T, Lyubchik A, Zhou Y, He S, McNamara W, et al. Schwann cells induce cancer cell dispersion and invasion. J Clin Invest. 2016;126:1538-54 pubmed publisher
immunocytochemistry; rat; 1:200; fig 2	MÃ¼ller C, Hochhaus N, Fontana X, Luhmann H, White R. SncRNA715 Inhibits Schwann Cell Myelin Basic Protein Synthesis. PLoS ONE. 2015;10:e0136900 pubmed publisher
immunohistochemistry - frozen section; human; 1:500; loading ...; fig 7d	Dobolyi A, Ostergaard E, Bagó A, Doczi T, Palkovits M, Gal A, et al. Exclusive neuronal expression of SUCLA2 in the human brain. Brain Struct Funct. 2015;220:135-51 pubmed publisher
immunohistochemistry; human; 1:500 immunohistochemistry; guinea pig; 1:500	Hoff S, Zeller F, Von Weyhern C, Wegner M, Schemann M, Michel K, et al. Quantitative assessment of glial cells in the human and guinea pig enteric nervous system with an anti-Sox8/9/10 antibody. J Comp Neurol. 2008;509:356-71 pubmed publisher
	Bird E, Iannitti T, Christmas C, Obara I, Andreev V, King A, et al. A Novel Role for Lymphotactin (XCL1) Signaling in the Nervous System: XCL1 Acts via its Receptor XCR1 to Increase Trigeminal Neuronal Excitability. Neuroscience. 2018;379:334-349 pubmed publisher
	Kemp K, Hares K, Redondo J, Cook A, Haynes H, Burton B, et al. Bone marrow transplantation stimulates neural repair in Friedreich's ataxia mice. Ann Neurol. 2018;83:779-793 pubmed publisher
	Forrest S, Osborne P, Keast J. Characterization of axons expressing the artemin receptor in the female rat urinary bladder: a comparison with other major neuronal populations. J Comp Neurol. 2014;522:3900-27 pubmed publisher
	Foudah D, Redondo J, Caldara C, Carini F, Tredici G, Miloso M. Human mesenchymal stem cells express neuronal markers after osteogenic and adipogenic differentiation. Cell Mol Biol Lett. 2013;18:163-86 pubmed publisher
	Tilkorn D, Daigeler A, Stricker I, Schaffran A, Schmitz I, Steinstraesser L, et al. Establishing efficient xenograft models with intrinsic vascularisation for growing primary human low-grade sarcomas. Anticancer Res. 2011;31:4061-6 pubmed
	ENGLE M, Merrill M, Marquez de Prado B, Hammond D. Spinal nerve ligation decreases γ-aminobutyric acidB receptors on specific populations of immunohistochemically identified neurons in L5 dorsal root ganglion of the rat. J Comp Neurol. 2012;520:1663-77 pubmed publisher
	Honoré S, Zelarayan L, Genta S, Sánchez S. Neuronal loss and abnormal BMP/Smad signaling in the myenteric plexus of diabetic rats. Auton Neurosci. 2011;164:51-61 pubmed publisher
	Guseva D, Zerwas M, Xiao M, Jakovcevski I, Irintchev A, Schachner M. Adhesion molecule L1 overexpressed under the control of the neuronal Thy-1 promoter improves myelination after peripheral nerve injury in adult mice. Exp Neurol. 2011;229:339-52 pubmed publisher
	Sbai O, Devi T, Melone M, Feron F, Khrestchatisky M, Singh L, et al. RAGE-TXNIP axis is required for S100B-promoted Schwann cell migration, fibronectin expression and cytokine secretion. J Cell Sci. 2010;123:4332-9 pubmed publisher
	Maor E, Ivorra A, Mitchell J, Rubinsky B. Vascular smooth muscle cells ablation with endovascular nonthermal irreversible electroporation. J Vasc Interv Radiol. 2010;21:1708-15 pubmed publisher
	Chi G, Kim M, Kim D, Jiang M, Son Y. Schwann cells differentiated from spheroid-forming cells of rat subcutaneous fat tissue myelinate axons in the spinal cord injury. Exp Neurol. 2010;222:304-17 pubmed publisher
	Platel J, Gordon V, Heintz T, Bordey A. GFAP-GFP neural progenitors are antigenically homogeneous and anchored in their enclosed mosaic niche. Glia. 2009;57:66-78 pubmed publisher
	Lankford K, Sasaki M, Radtke C, Kocsis J. Olfactory ensheathing cells exhibit unique migratory, phagocytic, and myelinating properties in the X-irradiated spinal cord not shared by Schwann cells. Glia. 2008;56:1664-78 pubmed publisher
	Perrone L, Peluso G, Melone M. RAGE recycles at the plasma membrane in S100B secretory vesicles and promotes Schwann cells morphological changes. J Cell Physiol. 2008;217:60-71 pubmed publisher
	Nasser Y, Keenan C, Ma A, McCafferty D, Sharkey K. Expression of a functional metabotropic glutamate receptor 5 on enteric glia is altered in states of inflammation. Glia. 2007;55:859-72 pubmed
	Zahs K, Ceelen P. Gap junctional coupling and connexin immunoreactivity in rabbit retinal glia. Vis Neurosci. 2006;23:1-10 pubmed
	Nasser Y, Ho W, Sharkey K. Distribution of adrenergic receptors in the enteric nervous system of the guinea pig, mouse, and rat. J Comp Neurol. 2006;495:529-53 pubmed
	Lyck L, Jelsing J, Jensen P, Lambertsen K, Pakkenberg B, Finsen B. Immunohistochemical visualization of neurons and specific glial cells for stereological application in the porcine neocortex. J Neurosci Methods. 2006;152:229-42 pubmed
	Pannunzio M, Jou I, Long A, Wind T, Beck G, Balian G. A new method of selecting Schwann cells from adult mouse sciatic nerve. J Neurosci Methods. 2005;149:74-81 pubmed

product information

Catalog Number :

MAB079-1

Subcategory :

Metabolism

Product Name :

Anti-S-100 Protein Antibody, clone 15E2E2

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P23297

Host Name :

Mouse

Antigen :

S-100 Protein

Clone :

15E2E2

Conjugate :

Purified

Isotype :

IgG2aκ

Product Description :

Anti-S-100 Protein Antibody, clone 15E2E2

Cross Reactivity :

Human;Bovine;Mouse;Rat;Canine;Rabbit;Feline

Background :

S-100 protein is a member of the EF-hand calcium-binding protein superfamily that is widely distributed and conserved in the central nervous system of vertebrates. The protein exists in both heterodimeric and homodimeric forms. The two subunits of S-100 protein are the products of separate genes that are differentially expressed by various cells. The beta subunit is present in all S-100 positive cells and tumors. In contrast, the alpha subunit is detectable only in heart, skeletal muscle and brain. In addition to its calcium binding properties, S-100 protein has a high-affinity binding site for zinc and is involved in the regulation of protein phosphorylation in the brain. The protein apparently plays a role in cell differentiation and growth, cytoskeletal structure and function, and has been implicated in neuropathological diseases.

ALT Names :

Calcium Binding Protein A1/B1

Immunogen :

Purified bovine S-100 protein

Specificity :

Recognizes intact, alpha and beta subunits of bovine, human, and murine S-100 protein, as determined by immunoprecipitation profiles.

Package Size :

100 µL

Uses :

Immunohistochemistry;Immunohistochemistry (Paraffin);Immunoprecipitation;Western Blotting

Storage :

Stable for 1 year at 2-8ºC from date of receipt.