LDL Receptor Mouse mAb (15C8) | EMD Millipore LP02-100UG product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

LDL Receptor Mouse mAb (15C8)

catalog :

LP02-100UG

quantity :

100 ug

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

reactivity :

human, mouse, rat, bovine

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry

citations: 1

Published Application/Species/Sample/Dilution	Reference
western blot; bovine; 1:100; loading ...; fig 1c	Horihata K, Yoshioka S, Sano M, Yamamoto Y, Kimura K, Skarzynski D, et al. Expressions of lipoprotein receptors and cholesterol efflux regulatory proteins during luteolysis in bovine corpus luteum. Reprod Fertil Dev. 2017;29:1280-1286 pubmed publisher

product information

Catalog Number :

LP02-100UG

Category :

Antibodies

Subcategory :

Neuroscience

Product Name :

Anti-LDL Receptor Mouse mAb (15C8)

Product Type :

Antibodies

Clonality :

Monoclonal

Gene ID :

3949 (Hu), 16835 (Ms), 300438 (Rt)

Host Name :

Clone :

15C8

Conjugate :

Purified

Isotype :

IgG2a

Product Description :

Anti-LDL Receptor Mouse mAb (15C8)

Cross Reactivity :

Bovine, Human

Background :

The low density lipoprotein receptor is responsible for mediating the uptake of LDL, a cholesterol carrying plasma lipoprotein. The receptor is a member of a class of cell surface proteins which are concentrated in clathrin coated pits and carry external ligands into cells by receptor-mediated endocytosis. The purified receptor is a glycoprotein with a molecular weight of 160,000. It is synthesized as a precursor of molecular weight 120,000 that is then glycosylated to the mature form by addition of N-linked and O-linked sugars in the Golgi apparatus. Unlike other hepatic lectins, the orientation of the LDL-R is such that the amino terminus is to the exterior of the cell. It has recently been determined that the LDL-R has sequence homology with the epidermal growth factor receptor precursor.

ALT Names :

FH, FHC, Hlb301, LDL RECEPTOR, LDLCQ2, LDLRA, low density lipoprotein receptor

Immunogen :

a trypic digest of bovine low density lipoprotein receptor

Specificity :

Recognizes the ~160 kDa LDL Receptor protein.

Package Size :

100 ug

Uses :

ELISA, FC, IH, WB, IC, IP

Storage :

Do not freeze