Cytokeratin 18 (Ab-2) Mouse mAb (DC10) | EMD Millipore IF14-100UG product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Cytokeratin 18 (Ab-2) Mouse mAb (DC10)

catalog :

IF14-100UG

quantity :

100 ug

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry

product information

Catalog Number :

IF14-100UG

Category :

Antibodies

Subcategory :

Cell Structure

Product Name :

Anti-Cytokeratin 18 (Ab-2) Mouse mAb (DC10)

Product Type :

Antibodies

Clonality :

Monoclonal

Gene ID :

3875 (Hu), 16668 (Ms), 294853 (Rt)

Host Name :

Clone :

DC10

Conjugate :

Purified

Isotype :

IgG1

Product Description :

Anti-Cytokeratin 18 (Ab-2) Mouse mAb (DC10)

Cross Reactivity :

Human

Background :

Intermediate (10 nm) filaments (IFs) are present in, and provide information concerning the origin of, most vertebrate cells. At present, five major cell types can be distinguished by their intermediate filament components. These include epithelial cells (cytokeratins), neurons (neurofilaments), glial cells (GFA), skeletal, visceral and certain vascular smooth muscle cells (desmin) and various nonepithelial cells, including cells of mesenchymal origin (vimentin). Cytokeratins (CK) are intermediate filaments of epithelial cells, both in keratinizing tissue (i.e. skin) and non-keratinizing cells (i.e. mesothelial cells). Although not a traditional marker for endothelial cells, cytokeratins have also been found in some microvascular endothelial cells. At least 20 different cytokeratins (CK) in the molecular range of ~40-70 kDa and isoelectric points of 5-8.5 can be identified using two dimensional gel electrophoresis.

ALT Names :

Ck D, CK18, CYK18, CYTOKERATIN 18, EndoB, K18, K1cr, KERATIN 18, Keratin complex 1 acidic gene 18, KRT1-18, MGC109143, keratin 18

Immunogen :

human PMC42 breast cancer cells

Specificity :

Recognizes the ~45 kDa cytokeratin 18 protein.

Package Size :

100 ug

Uses :

IH, WB, IH(P)

Storage :

For long-term storage, aliquot and freeze (-20°C). Avoid freeze/thaw cycles.