Estrogen Receptor beta (Ab-2) Mouse mAb (9.88) | EMD Millipore GR39-100UL product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Estrogen Receptor beta (Ab-2) Mouse mAb (9.88)

catalog :

GR39-100UL

quantity :

100 uL

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunoprecipitation

product information

Catalog Number :

GR39-100UL

Category :

Antibodies

Subcategory :

Epigenetics & Nuclear Function

Product Name :

Anti-Estrogen Receptor beta (Ab-2) Mouse mAb (9.88)

Product Type :

Antibodies

Clonality :

Monoclonal

Gene ID :

2100 (Hu), 13983 (Ms), 25149 (Rt)

Host Name :

Clone :

9.88

Conjugate :

Undiluted Ascites

Isotype :

IgM

Product Description :

Anti-Estrogen Receptor beta (Ab-2) Mouse mAb (9.88)

Cross Reactivity :

Human, Mouse, Rat

Background :

Steroids regulate important neuronal functions including the organization of neural circuits during development and the regulation of synapse organization in the adult. Steroid hormones may promote cell survival and differentiation of both neurons and glial cells, regulate synaptogenesis, prevent synapse elimination, cause axonal and dendritic growth, and play a role during regeneration of the nervous system. Steroid hormone receptors are members of a large family of nuclear ligand-activated transcription factors that includes the androgen, estrogen, glucocorticoid, and progesterone receptors. In the absence of hormone, steroid receptors are associated in complexes with heat shock proteins and immunophilins. Steroid binding results in the dissociation of the heat-shock protein, receptor dimerization, and binding to specific hormone response elements (HRE) to produce a transcriptionally active complex that leads to the activation or repression of target genes.

ALT Names :

BETA ESTROGEN RECEPTOR, ER-BETA, ERB, ERB2, ER[b], ESR-BETA, ESRB, ESTRB, ESTROGEN RECEPTOR BETA, NR3A2, estrogen receptor 2 (ER beta)

Immunogen :

recombinant, human estrogen receptor beta

Specificity :

Recognizes the ~53 kDa estrogen receptor beta protein.

Package Size :

100 uL

Uses :

WB, IP

Storage :

Following initial thaw, aliquot and freeze (-20°C). Avoid repeated freeze-thaw.