Vitamin D Receptor (Ab-1) Rat mAb (9A7ɣE10.4) | EMD Millipore GR37-100UG product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Vitamin D Receptor (Ab-1) Rat mAb (9A7ɣE10.4)

catalog :

GR37-100UG

quantity :

100 ug

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunoprecipitation, EMSA

product information

Catalog Number :

GR37-100UG

Category :

Antibodies

Subcategory :

Neuroscience

Product Name :

Anti-Vitamin D Receptor (Ab-1) Rat mAb (9A7ɣE10.4)

Product Type :

Antibodies

Clonality :

Monoclonal

Gene ID :

7421 (Hu), 22337 (Ms), 24873 (Rt)

Host Name :

Clone :

9A7ɣE10.4

Conjugate :

Purified

Isotype :

IgG1

Product Description :

Anti-Vitamin D Receptor (Ab-1) Rat mAb (9A7ɣE10.4)

Cross Reactivity :

Amphibian, Chicken, Hamster, Human, Mouse, Porcine, Rat

Background :

Vitamin D Receptor (VDR) also known as 1,25-dihydroxyvitamin D3 receptor is a member of the nuclear steroid hormone receptor superfamily which regulate gene transcription by interacting with response elements in gene promoters. VDR binds with the retinoid X receptor (RXR) from specific DNA sequences in the promoter region of vitamin D response elements (VDREs). VDR has been implicated in a variety of physiological functions including effects on growth and differentiation in normal and malignant cells. These effects are mediated through a single ligand, calcitriol. Cacitriol the active metabolite of vitamin D is a known regulator of calcium homeostasis but it also has numerous other functions including inhibition of proliferation of cancer cells and suppression of T-cell proliferation and cytokine production.

ALT Names :

NR1I1, VD3R, VITAMIN D RECEPTOR, vitamin D (1,25- dihydroxyvitamin D3) receptor

Immunogen :

purified, chick intestine vitamin D receptor

Specificity :

Recognizes both the occupied and unoccupied forms of vitamin D receptor.

Package Size :

100 ug

Uses :

IH, EMSA, WB, IP, IH(P)

Storage :

Following initial use, aliquot and freeze (-20°C). Avoid repeated freeze-thaw.