Glucocorticoid Receptor (Ab-2) Mouse mAb (BuGR2) | EMD Millipore GR32L-100UG product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Glucocorticoid Receptor (Ab-2) Mouse mAb (BuGR2)

catalog :

GR32L-100UG

quantity :

100 ug

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation

product information

Catalog Number :

GR32L-100UG

Category :

Antibodies

Subcategory :

Epigenetics & Nuclear Function

Product Name :

Anti-Glucocorticoid Receptor (Ab-2) Mouse mAb (BuGR2)

Product Type :

Antibodies

Clonality :

Monoclonal

Gene ID :

2908 (Hu), 14815 (Ms), 24413 (Rt)

Host Name :

Clone :

BuGR2

Conjugate :

Purified

Isotype :

IgG2a

Product Description :

Anti-Glucocorticoid Receptor (Ab-2) Mouse mAb (BuGR2)

Cross Reactivity :

Guinea Pig, Mouse, Rabbit, Rat, Sheep

Background :

Steroids regulate important neuronal functions including the organization of neural circuits during development and the regulation of synapse organization in the adult. Steroid hormones may promote cell survival and differentiation of both neurons and glial cells, regulate synaptogenesis, prevent synapse elimination, cause axonal and dendritic growth, and play a role during regeneration of the nervous system. Steroid hormone receptors are members of a large family of nuclear ligand-activated transcription factors that includes the androgen, estrogen, glucocorticoid, and progesterone receptors. In the absence of hormone, steroid receptors are associated in complexes with heat shock proteins and immunophilins. Steroid binding results in the dissociation of the heat-shock protein, receptor dimerization, and binding to specific hormone response elements (HRE) to produce a transcriptionally active complex that leads to the activation or repression of target genes.

ALT Names :

GCCR, GCR, GCR ALPHA, GLUCOCORTICOID RECEPTOR, GLUCOCORTOCOID RECEPTOR, GR, Gr alpha, Gr beta, GR-A, GRL, Grl-1, HGR, Type ii corticosteroid receptor, nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)

Immunogen :

partially purified, rat glucocorticoid receptor

Specificity :

Recognizes the ~94-97 kDa glucocorticoid receptor.

Package Size :

100 ug

Uses :

IH, WB, IC, IP, IH(P)

Storage :

Resuspend the lyophilized antibody with 0.1 ml sterile PBS, pH 7.2. Be careful to reconstitute the entire contents of the vial; during shipment and handling, portions of the lyophilized pellet may have become dislodged and may not be in the bottom of the vial. Following reconstitution, aliquot and freeze (-20°C). Avoid freeze/thaw cycles of solutions.