Progesterone Receptor (Ab-1) Mouse mAb (PR4-12) | EMD Millipore GR18-100UG product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Progesterone Receptor (Ab-1) Mouse mAb (PR4-12)

catalog :

GR18-100UG

quantity :

100 ug

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry

product information

Catalog Number :

GR18-100UG

Category :

Antibodies

Subcategory :

Epigenetics & Nuclear Function

Product Name :

Anti-Progesterone Receptor (Ab-1) Mouse mAb (PR4-12)

Product Type :

Antibodies

Clonality :

Monoclonal

Gene ID :

5241 (Hu), 18667 (Ms), 25154 (Rt)

Host Name :

Clone :

PR4-12

Conjugate :

Purified

Isotype :

IgG1

Product Description :

Anti-Progesterone Receptor (Ab-1) Mouse mAb (PR4-12)

Cross Reactivity :

Chicken, Feline, Human, Rat

Background :

The progesterone receptor (PR) is a member of the superfamily of steroid hormone receptors. In response to ligand binding, these nuclear receptors bind to their target DNA response element and modulate the transcription of specific genes. Hormone induced binding of receptor to its response element promotes the formation of a stable initiation complex, which allows for efficient transcription by RNA polymerase II. Steroid hormone receptors are characterized by a six domain structure labeled A through F. The A/B domain is responsible for trans-activation, C is the DNA binding region and the most highly conserved, D is involved in nuclear localization and E has a variety of functions including ligand binding, dimerization, interaction with HSP90 and trans-activation. There are two forms of the progesterone receptor; the A-receptor (~94 kDa) is a naturally occurring, truncated form of the B-receptor (~120 kDa). Both forms bind progesterone but may have distinct biological properties.

ALT Names :

9930019P03Rik, BB114106, ENSMUSG00000074510, LOC360433, NR3C3, Pgrb, PR, PR BETA, PR-A, PR-B, PROGESTERONE RECEPTOR, Progesterone receptor A, progesterone receptor

Immunogen :

recombinant, human progesterone receptor

Specificity :

Recognizes the ~94 kDa progesteron receptor A and the ~120 kDa progesterone receptor B.

Package Size :

100 ug

Uses :

WB, IH(P)

Storage :

Do not freeze