EGFR (Ab-3) Mouse mAb (225) | EMD Millipore GR13L-100UG product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

EGFR (Ab-3) Mouse mAb (225)

catalog :

GR13L-100UG

quantity :

100 ug

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

neutralization, immunoprecipitation

product information

Catalog Number :

GR13L-100UG

Category :

Antibodies

Subcategory :

Cell Signaling

Product Name :

Anti-EGFR (Ab-3) Mouse mAb (225)

Product Type :

Antibodies

Clonality :

Monoclonal

Gene ID :

1956 (Hu), 13649 (Ms), 24329 (Rt)

Host Name :

Clone :

225

Conjugate :

Purified

Isotype :

IgG1

Product Description :

Anti-EGFR (Ab-3) Mouse mAb (225)

Cross Reactivity :

Human

Background :

Epidermal growth factor (EGF) initiates its effects on cell growth through interaction with a 170,000 dalton cell surface glycoprotein receptor. Binding of EGF or transforming growth factor a to the receptor activates a tyrosine-specific protein kinase intrinsic to the EGF receptor protein. The phosphotyrosine content of target cells increases rapidly and the EGF receptor is phosphorylated on tyrosine residues. Subsequent to binding, EGF receptor complexes are internalized and cell proliferation takes place with partially-purified EGF receptor from human A431 epidermal carcinoma cells.

ALT Names :

EGF RECEPTOR, EGF-TK, EGFR1, EGFRec, ER2, ERBB, ERBB1, Errp, HER1, MENA, PIG61, wa-2, Wa5, epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)

Immunogen :

partially purified, human EGFR from A431 cells

Specificity :

Recognizes the ~170 kDa epidermal growth factor receptor protein.

Package Size :

100 ug

Uses :

IP, NEUT

Storage :

Reconstitute the lyophilized antibody with sterile PBS, pH 7.4, or sterile 20 mM Tris-saline (20 mM Tris containing 0.15 M NaCl), pH 7.4, to yield a final concentration of 100 ug/ml. Lyophilized antibodies should be resuspended at 4°C with occasional gentle mixing for at least 2 h. Following reconstitution, aliquot and freeze (-20°C) for long-term storage or refrigerate at 4°C with 0.1% azide for short-term storage. Avoid freeze/thaw cycles of solutions.