HGF (Scatter Factor) (Ab-1) Mouse mAb (4C12.1) | EMD Millipore GF39-100UG product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

HGF (Scatter Factor) (Ab-1) Mouse mAb (4C12.1)

catalog :

GF39-100UG

quantity :

100 ug

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunoprecipitation

product information

Catalog Number :

GF39-100UG

Category :

Antibodies

Subcategory :

Cell Signaling

Product Name :

Anti-HGF (Scatter Factor) (Ab-1) Mouse mAb (4C12.1)

Product Type :

Antibodies

Clonality :

Monoclonal

Gene ID :

3082 (Hu), 15234 (Ms), 24446 (Rt)

Host Name :

Clone :

4C12.1

Conjugate :

Purified

Isotype :

IgG2b

Product Description :

Anti-HGF (Scatter Factor) (Ab-1) Mouse mAb (4C12.1)

Cross Reactivity :

Human

Background :

Hepatocyte Growth Factor (HGF), also known as Scatter Factor (SF) and Hepatopoietin A, is a pleiotrophic growth factor which is produced by mesodermally derived cells such as endothelial cells, Kupffer cells/macrophages, and hepatic fat-storing cells. HGF/SF is a potent effector of growth, movement, differentiation and invasiveness of epithelial and cancer cells. It can induce epithelial-mesenchymal conversion of epithelial cells in culture, support epithelial branching duct formation in the developing lung and elicit a potent organotrophic function for regeneration of liver, kidney and lung through epithelial-stromal interactions. HGF/SF is also a potent angiogenic molecule whose activity such as cell migration, proliferation, protease production, invasion and capillary tube formation is mediated through direct actions on vascular endothelial cells. Recent evidence has shown that HGF/SF is overexpressed in invasive human cancer, relative to non-invasive and benign conditions.

ALT Names :

C230052L06Rik, DFNB39, F-TCF, HEPATOCYTE GROWTH FACTOR, HGF/SF, HGFB, HPTA, NK1, NK2, SF, SF/HGF, hepatocyte growth factor (hepapoietin A, scatter factor)

Immunogen :

recombinant, human HGF protein

Specificity :

Recognizes the ~82 kDa HGF protein.

Package Size :

100 ug

Uses :

WB, IP

Storage :

Following initial use, aliquot and freeze (-20°C) for long-term storage if desired. Avoid freeze/thaw.