VEGF (Ab-3) Mouse mAb (14-124) | EMD Millipore GF25-100UG product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

VEGF (Ab-3) Mouse mAb (14-124)

catalog :

GF25-100UG

quantity :

100 ug

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry

citations: 1

Published Application/Species/Sample/Dilution	Reference
western blot; human; 1:2000; fig 4	Tao Y, Hu K, Tan F, Zhang S, Zhou M, Luo J, et al. SH3-domain binding protein 1 in the tumor microenvironment promotes hepatocellular carcinoma metastasis through WAVE2 pathway. Oncotarget. 2016;7:18356-70 pubmed publisher

product information

Catalog Number :

GF25-100UG

Category :

Antibodies

Subcategory :

Cell Signaling

Product Name :

Anti-VEGF (Ab-3) Mouse mAb (14-124)

Product Type :

Antibodies

Clonality :

Monoclonal

Gene ID :

7422 (Hu), 22339 (Ms), 83785 (Rt)

Host Name :

Clone :

14-124

Conjugate :

Purified

Isotype :

IgG1

Product Description :

Anti-VEGF (Ab-3) Mouse mAb (14-124)

Cross Reactivity :

Human

Background :

Vascular endothelial growth factor (VEGF), also known as vascular permeability factor (VPF), is a secreted heparin binding cytokine expressed in tumor and animal cells. VEGF has been implicated in the control of angiogenesis due to its selective mitogenic stimulation of vascular endothelial cells and enhancement of vascular permeability. Other effects of VEGF on vascular endothelial cells include; increasing intracellular calcium, stimulating inositol triphosphate formation, induction of von Willebrand factor release, and stimulating tissue factor expression. VEGF is a ~46 kDa dimer of two identical disulfide-linked subunits existing in four molecular species; 121, 165, 189, and 206 amino acid residues long.

ALT Names :

Gd-vegf, MGC70609, MVCD1, VEGF, Vegf-3, VEGF1, VEGF120, VEGF164, Vegf165, Vegf188, Vegfa 188, VPF, VPF/VEGF, vascular endothelial growth factor A

Immunogen :

a synthetic peptide corresponding to amino acids from the N-terminus of human VEGF 165

Specificity :

Recognizes the ~31-50 kDa VEGF 121 , VEGF 165 , VEGF 189 , and VEGF 206 proteins.

Package Size :

100 ug

Uses :

WB, IH(P)

Storage :

Do not freeze