TGF-beta3 (Ab-1) Mouse mAb (236-5.2) | EMD Millipore GF16-200UG product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

TGF-beta3 (Ab-1) Mouse mAb (236-5.2)

catalog :

GF16-200UG

quantity :

200 ug

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunoprecipitation

product information

Catalog Number :

GF16-200UG

Category :

Antibodies

Subcategory :

Inflammation & Immunology

Product Name :

Anti-TGF-beta3 (Ab-1) Mouse mAb (236-5.2)

Product Type :

Antibodies

Clonality :

Monoclonal

Gene ID :

7043 (Hu), 21809 (Ms), 25717 (Rt)

Host Name :

Clone :

236-5.2

Conjugate :

Purified

Isotype :

IgG1

Product Description :

Anti-TGF-beta3 (Ab-1) Mouse mAb (236-5.2)

Cross Reactivity :

Human, Mouse, Rat

Background :

Transforming growth factorbetas are a family of proteins originally characterized by their ability to act synergistically with EGF or TGFalpha. TGFbetas have been found to produce multiple biological effects including mitogenesis, growth inhibition, chemotaxis and induction or inhibition of differentiation. In their mature form TGFbetas are acid- and heat-stable disulfide-linked homodimeric proteins (Mr = ~25 kDa), with each homodimer consisting of 112 amino acid residues. Two homodimeric forms of TGFbeta have been identified (TGFbeta1 and TGFbeta2) which show significant amino acid sequence homology. A new member of the family, TGFbeta3 has recently been cloned and characterized. There is greater amino acid homology between TGFbeta3 and TGFbeta2 as compared with TGFbeta1. All TGFbetas are released by cells in a biologically latent form. Most cells have high affinity receptors for TGFbeta1, beta2, and beta3.

ALT Names :

ARVD, FLJ16571, MGC105479, MGC118722, TGF BETA 3, TRANSFORMING GROWTH FACTOR BETA 3, transforming growth factor, beta 3

Immunogen :

recombinant, human TGF-beta3

Specificity :

Recognizes TGF-beta2 and TGF-beta3.

Package Size :

200 ug

Uses :

IH, WB, IP, IH(P)

Storage :

Following initial thaw, aliquot and freeze (-20°C). Avoid repeated freeze-thaw.