TGF-alpha (Ab-1) Mouse mAb (134A-2B3) | EMD Millipore GF06-100UG product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

TGF-alpha (Ab-1) Mouse mAb (134A-2B3)

catalog :

GF06-100UG

quantity :

100 ug

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot

product information

Catalog Number :

GF06-100UG

Category :

Antibodies

Subcategory :

Inflammation & Immunology

Product Name :

Anti-TGF-alpha (Ab-1) Mouse mAb (134A-2B3)

Product Type :

Antibodies

Clonality :

Monoclonal

Gene ID :

7039 (Hu), 21802 (Ms), 24827 (Rt)

Host Name :

Clone :

134A-2B3

Conjugate :

Purified

Isotype :

IgG1

Product Description :

Anti-TGF-alpha (Ab-1) Mouse mAb (134A-2B3)

Cross Reactivity :

Human, Rat

Background :

Transforming growth factor-alpha (TGFalpha) is an acid- and heat-stable 50 amino acid protein of 5500 MW originally found in rodents and humans. TGFalphais 33% homologous at the amino acid level to epidermal growth factor (EGF). TGFalpha binds to the EGF receptor, mediates tyrosine phosphorylation of the receptor, and promotes anchorage-independent growth of normal rat fibroblasts in soft agar in the presence of transforming growth factor-beta. TGFalpha is secreted by a variety of transformed cells and tumors, embryonic cells and some normal adult cells. TGFalpha bioactivity has been found in the urine of cancer patients. It has been suggested that it may act as an autocrine growth factor for the induction or maintenance of malignancy.

ALT Names :

RATTGFAA, TFGA, TGF ALPHA, TGFAA, wa-1, transforming growth factor, alpha

Immunogen :

recombinant, human TGF-alpha (~6 kDa mature form)

Specificity :

Recognizes the ~6 kDa denatured and native forms of TGFalpha protein.

Package Size :

100 ug

Uses :

Storage :

We recommend resuspending the lyophilized antibody with sterile PBS, pH 7.4, to yield a final concentration of 100 ug/ml; product will be more stable if 0.1% sodium azide is included (do not add azide if antibody is to be used with viable cells). Lyophilized antibodies should be resuspended at 4°C with occasional gentle mixing for at least 2 h. Following reconstitution, refrigerate (4°C) or aliquot and freeze (-20°C). Do not freeze.